oxidative stress Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma (Mammalian Phenotype Ontology, MP_0003674)
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Genes

19 genes associated with the disease oxidative stress in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
CYBA cytochrome b-245, alpha polypeptide
GSTM1 glutathione S-transferase mu 1
GSTO1 glutathione S-transferase omega 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO1 NAD(P)H dehydrogenase, quinone 1
PLAT plasminogen activator, tissue
PON1 paraoxonase 1
PON2 paraoxonase 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
TNF tumor necrosis factor
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VEGFA vascular endothelial growth factor A