osteoarthritis Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An arthritis that has_material_basis_in worn out cartilage located_in joint. (Human Disease Ontology, DOID_8398)
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Genes

46 genes associated with the disease osteoarthritis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AR androgen receptor
ASPN asporin
BMP5 bone morphogenetic protein 5
CALCA calcitonin-related polypeptide alpha
CALM1 calmodulin 1 (phosphorylase kinase, delta)
COG5 component of oligomeric golgi complex 5
COL11A1 collagen, type XI, alpha 1
COL11A2 collagen, type XI, alpha 2
COL1A1 collagen, type I, alpha 1
COL2A1 collagen, type II, alpha 1
COL9A1 collagen, type IX, alpha 1
COL9A2 collagen, type IX, alpha 2
COL9A3 collagen, type IX, alpha 3
CRP C-reactive protein, pentraxin-related
DIO2 deiodinase, iodothyronine, type II
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FRZB frizzled-related protein
GDF5 growth differentiation factor 5
HFE hemochromatosis
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL4R interleukin 4 receptor
IL6 interleukin 6
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
MATN3 matrilin 3
MCF2L MCF.2 cell line derived transforming sequence-like
MMP2 matrix metallopeptidase 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIMP VCP-interacting membrane selenoprotein