optic nerve atrophy Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description acquired diminution of the size of the second cranial nerve which is responsible for conveying visual information from the retina to the brain, associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes (Mammalian Phenotype Ontology, MP_0001059)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001059
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Genes

6 gene mutations causing the optic nerve atrophy phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BBS4 Bardet-Biedl syndrome 4
CLCN7 chloride channel, voltage-sensitive 7
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
PRSS56 protease, serine, 56
RPL24 ribosomal protein L24
RYBP RING1 and YY1 binding protein