opioid abuse Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A substance abuse that involves the recurring use of opioid drugs despite negative consequences. (Human Disease Ontology, DOID_11206)
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Genes

52 genes co-occuring with the disease opioid abuse in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
OPRM1 opioid receptor, mu 1 1.82323
NPFF neuropeptide FF-amide peptide precursor 1.47682
OTP orthopedia homeobox 1.32629
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 1.1367
FRS2 fibroblast growth factor receptor substrate 2 1.09293
CCKAR cholecystokinin A receptor 0.950352
PNOC prepronociceptin 0.89582
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.879833
CCKBR cholecystokinin B receptor 0.864274
PDYN prodynorphin 0.812232
ADCY5 adenylate cyclase 5 0.778613
NKX2-2 NK2 homeobox 2 0.697109
OPRL1 opiate receptor-like 1 0.685491
PRDM16 PR domain containing 16 0.676706
OPRK1 opioid receptor, kappa 1 0.673518
CCK cholecystokinin 0.651694
TAC1 tachykinin, precursor 1 0.650903
SYNE1 spectrin repeat containing, nuclear envelope 1 0.648928
CCR3 chemokine (C-C motif) receptor 3 0.633169
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.630813
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.623359
PDCL phosducin-like 0.619442
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.59952
SIX1 SIX homeobox 1 0.574217
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.573828
EGR2 early growth response 2 0.569163
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.561004
ARRB1 arrestin, beta 1 0.515725
IRF7 interferon regulatory factor 7 0.488169
PENK proenkephalin 0.465416
PSENEN presenilin enhancer gamma secretase subunit 0.45447
LAX1 lymphocyte transmembrane adaptor 1 0.437906
ATF3 activating transcription factor 3 0.42289
DCXR dicarbonyl/L-xylulose reductase 0.404931
CREM cAMP responsive element modulator 0.381852
CSN1S1 casein alpha s1 0.350084
TACR1 tachykinin receptor 1 0.346777
NPS neuropeptide S 0.337608
POMC proopiomelanocortin 0.336144
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.305948
CCL4 chemokine (C-C motif) ligand 4 0.301976
BDNF brain-derived neurotrophic factor 0.290821
CXCR2 chemokine (C-X-C motif) receptor 2 0.263014
TLR4 toll-like receptor 4 0.258064
FOS FBJ murine osteosarcoma viral oncogene homolog 0.257711
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.236312
SOX2 SRY (sex determining region Y)-box 2 0.227642
TLR3 toll-like receptor 3 0.200982
CCL2 chemokine (C-C motif) ligand 2 0.190786
MECP2 methyl CpG binding protein 2 0.190476
CCL5 chemokine (C-C motif) ligand 5 0.187719
DRD2 dopamine receptor D2 0.161139