onion bulb formation Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Repeated episodes of segmental demyelination and remyelination lead to the accumulation of supernumerary Schwann cells around axons, which is referred to as onion bulb formation. This finding affects peripheral nerves. (Human Phenotype Ontology, HP_0003383)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0003383
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Genes

25 genes associated with the onion bulb formation phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
C12ORF65 chromosome 12 open reading frame 65
DCAF8 DDB1 and CUL4 associated factor 8
DNM2 dynamin 2
EGR2 early growth response 2
FGD4 FYVE, RhoGEF and PH domain containing 4
FIG4 FIG4 phosphoinositide 5-phosphatase
GDAP1 ganglioside induced differentiation associated protein 1
GJB1 gap junction protein, beta 1, 32kDa
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
INF2 inverted formin, FH2 and WH2 domain containing
KIF1B kinesin family member 1B
LITAF lipopolysaccharide-induced TNF factor
LMNA lamin A/C
MFN2 mitofusin 2
MPZ myelin protein zero
NDRG1 N-myc downstream regulated 1
NEFL neurofilament, light polypeptide
PMP22 peripheral myelin protein 22
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRX periaxin
SBF1 SET binding factor 1
SBF2 SET binding factor 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6