olivopontocerebellar atrophy Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A spinocerebellar ataxia that is characterized by progressive cerebellar ataxia, leading to clumsiness in body movements, veering from midline when walking, wide-based stance, and falls without signs of paralysis or weakness and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in degeneration of neuron in the cerebellum, pons and inferior olives. (Human Disease Ontology, DOID_14784)
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Genes

91 genes co-occuring with the disease olivopontocerebellar atrophy in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ATXN1 ataxin 1 2.01431
ATXN2 ataxin 2 1.83727
ATXN3 ataxin 3 1.65789
CALB1 calbindin 1, 28kDa 1.38428
TTC19 tetratricopeptide repeat domain 19 1.1524
OPCML opioid binding protein/cell adhesion molecule-like 1.03998
C10ORF2 chromosome 10 open reading frame 2 1.03914
MAP1B microtubule-associated protein 1B 1.0109
NTM neurotrimin 0.991909
SPTBN2 spectrin, beta, non-erythrocytic 2 0.97002
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 0.97002
PVALB parvalbumin 0.96918
STRN striatin, calmodulin binding protein 0.927105
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 0.922149
TRH thyrotropin-releasing hormone 0.920085
ATN1 atrophin 1 0.868368
NUP62 nucleoporin 62kDa 0.858952
VRK1 vaccinia related kinase 1 0.849536
RNF4 ring finger protein 4 0.840115
PMM2 phosphomannomutase 2 0.829459
NOP56 NOP56 ribonucleoprotein 0.828229
CHAT choline O-acetyltransferase 0.823308
FGF14 fibroblast growth factor 14 0.808949
ATXN7 ataxin 7 0.799923
JPH3 junctophilin 3 0.790492
SACS sacsin molecular chaperone 0.785984
PDYN prodynorphin 0.784755
IFI44 interferon-induced protein 44 0.764718
ATXN10 ataxin 10 0.756564
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.745172
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 0.715618
GYPE glycophorin E (MNS blood group) 0.678302
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.675112
GLO1 glyoxalase I 0.674315
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.647743
ATXN2L ataxin 2-like 0.638282
MDH1 malate dehydrogenase 1, NAD (soluble) 0.632384
S100B S100 calcium binding protein B 0.630813
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.624927
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.595233
RAB3A RAB3A, member RAS oncogene family 0.592895
MAP2 microtubule-associated protein 2 0.569941
LDHAL6B lactate dehydrogenase A-like 6B 0.566443
MAP4 microtubule-associated protein 4 0.546256
CS citrate synthase 0.533861
F13A1 coagulation factor XIII, A1 polypeptide 0.518805
LDHAL6A lactate dehydrogenase A-like 6A 0.507273
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.495029
AMPD1 adenosine monophosphate deaminase 1 0.490454
MBP myelin basic protein 0.478289
CRYAB crystallin, alpha B 0.477909
MED12 mediator complex subunit 12 0.469197
ASIC1 acid sensing (proton gated) ion channel 1 0.459751
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.454847
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.440162
KIAA0101 KIAA0101 0.437154
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.433397
TTPA tocopherol (alpha) transfer protein 0.42139
LDHC lactate dehydrogenase C 0.383337
LDHB lactate dehydrogenase B 0.367779
MAPT microtubule-associated protein tau 0.355235
TF transferrin 0.343106
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.338707
TH tyrosine hydroxylase 0.331025
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.32701
SYP synaptophysin 0.322273
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.317909
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.293694
TBP TATA box binding protein 0.292975
PARK7 parkinson protein 7 0.289027
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.284728
GAP43 growth associated protein 43 0.266558
SFTPC surfactant protein C 0.260891
SDF4 stromal cell derived factor 4 0.257005
PML promyelocytic leukemia 0.251718
STS steroid sulfatase (microsomal), isozyme S 0.233183
SQSTM1 sequestosome 1 0.232836
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.226952
FECH ferrochelatase 0.223853
CRH corticotropin releasing hormone 0.207912
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.206248
MUT methylmalonyl CoA mutase 0.198386
ARSH arylsulfatase family, member H 0.192657
LDHA lactate dehydrogenase A 0.187719
PRNP prion protein 0.187719
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.17952
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.175679
KLF4 Kruppel-like factor 4 (gut) 0.167682
GLUL glutamate-ammonia ligase 0.166319
TGM2 transglutaminase 2 0.162908
HSPA4 heat shock 70kDa protein 4 0.158266