nua4 histone acetyltransferase complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60). (Gene Ontology, GO_0035267)
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15 proteins localized to the nua4 histone acetyltransferase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
MEAF6 MYST/Esa1-associated factor 6 0.663342
ING3 inhibitor of growth family, member 3 0.663342
DMAP1 DNA methyltransferase 1 associated protein 1 0.663342
EP400 E1A binding protein p400 0.663342
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.663342
KAT5 K(lysine) acetyltransferase 5 0.663342
RUVBL2 RuvB-like AAA ATPase 2 0.663342
RUVBL1 RuvB-like AAA ATPase 1 0.663342
YEATS4 YEATS domain containing 4 0.663342
ACTB actin, beta 0.663342
TRRAP transformation/transcription domain-associated protein 0.663342
BRD8 bromodomain containing 8 0.663342
MORF4 mortality factor 4 (pseudogene) 0.663342
ACTL6A actin-like 6A 0.663342
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.03318