novobiocin-4569 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the novobiocin-4569 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADCK2 aarF domain containing kinase 2
AIM1L absent in melanoma 1-like
ANKRD7 ankyrin repeat domain 7
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
BTG2 BTG family, member 2
C1ORF54 chromosome 1 open reading frame 54
CAMKMT calmodulin-lysine N-methyltransferase
CC2D1A coiled-coil and C2 domain containing 1A
CDRT1 CMT1A duplicated region transcript 1
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIB2 calcium and integrin binding family member 2
CIDEB cell death-inducing DFFA-like effector b
CLCN7 chloride channel, voltage-sensitive 7
CLEC1A C-type lectin domain family 1, member A
CNGA1 cyclic nucleotide gated channel alpha 1
CNTNAP2 contactin associated protein-like 2
CORO2B coronin, actin binding protein, 2B
CPA2 carboxypeptidase A2 (pancreatic)
CREBZF CREB/ATF bZIP transcription factor
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
EPB41L1 erythrocyte membrane protein band 4.1-like 1
ESRRG estrogen-related receptor gamma
FAXDC2 fatty acid hydroxylase domain containing 2
FGFR4 fibroblast growth factor receptor 4
FLRT2 fibronectin leucine rich transmembrane protein 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GADD45G growth arrest and DNA-damage-inducible, gamma
GK3P glycerol kinase 3 pseudogene
GLYAT glycine-N-acyltransferase
GPATCH2L G patch domain containing 2-like
GPR6 G protein-coupled receptor 6
GRIP2 glutamate receptor interacting protein 2
HESX1 HESX homeobox 1
KIAA1654 KIAA1654 protein
KIF25 kinesin family member 25
KRT32 keratin 32, type I
LARGE like-glycosyltransferase
LEFTY2 left-right determination factor 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00115 long intergenic non-protein coding RNA 115
LPPR4 lipid phosphate phosphatase-related protein type 4
MAGOH2P mago-nashi homolog 2, pseudogene
MECP2 methyl CpG binding protein 2
MEGF6 multiple EGF-like-domains 6
MVB12B multivesicular body subunit 12B
MYOZ3 myozenin 3
NCALD neurocalcin delta
NEFM neurofilament, medium polypeptide
NUDC nudC nuclear distribution protein
PAX2 paired box 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHA5 protocadherin alpha 5
PCNX pecanex homolog (Drosophila)
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD2 programmed cell death 2
PEX16 peroxisomal biogenesis factor 16
PHF14 PHD finger protein 14
PLCL2 phospholipase C-like 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PLXNC1 plexin C1
PPP4R4 protein phosphatase 4, regulatory subunit 4
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PVT1 Pvt1 oncogene (non-protein coding)
RB1 retinoblastoma 1
RIBC2 RIB43A domain with coiled-coils 2
RPS3A ribosomal protein S3A
RUNDC3A RUN domain containing 3A
SAPCD1 suppressor APC domain containing 1
SARM1 sterile alpha and TIR motif containing 1
SCEL sciellin
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35F6 solute carrier family 35, member F6
SOGA1 suppressor of glucose, autophagy associated 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SSX3 synovial sarcoma, X breakpoint 3
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TCP10 t-complex 10
TK2 thymidine kinase 2, mitochondrial
TMLHE trimethyllysine hydroxylase, epsilon
TSNAXIP1 translin-associated factor X interacting protein 1
TTC38 tetratricopeptide repeat domain 38
TTLL1 tubulin tyrosine ligase-like family member 1
TXK TXK tyrosine kinase
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VPRBP Vpr (HIV-1) binding protein
VWA5A von Willebrand factor A domain containing 5A
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF37BP zinc finger protein 37B, pseudogene
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ADGRB2 adhesion G protein-coupled receptor B2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C19ORF40 chromosome 19 open reading frame 40
C22ORF29 chromosome 22 open reading frame 29
C22ORF46 chromosome 22 open reading frame 46
C5ORF45 chromosome 5 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CARD8 caspase recruitment domain family, member 8
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC176 coiled-coil domain containing 176
CHM choroideremia (Rab escort protein 1)
CLCA1 chloride channel accessory 1
CPZ carboxypeptidase Z
CRYBA2 crystallin, beta A2
CSF1R colony stimulating factor 1 receptor
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DOCK1 dedicator of cytokinesis 1
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELOVL4 ELOVL fatty acid elongase 4
EN1 engrailed homeobox 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERO1LB ERO1-like beta (S. cerevisiae)
FAM118A family with sequence similarity 118, member A
FAM186A family with sequence similarity 186, member A
FOXC1 forkhead box C1
GAL3ST4 galactose-3-O-sulfotransferase 4
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GMEB1 glucocorticoid modulatory element binding protein 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GREB1L growth regulation by estrogen in breast cancer-like
GRTP1 growth hormone regulated TBC protein 1
GTF2I general transcription factor IIi
HDAC7 histone deacetylase 7
HIST1H1T histone cluster 1, H1t
HIST1H4A histone cluster 1, H4a
HOOK1 hook microtubule-tethering protein 1
HOXC4 homeobox C4
HOXC8 homeobox C8
IFI44L interferon-induced protein 44-like
INCENP inner centromere protein antigens 135/155kDa
IREB2 iron-responsive element binding protein 2
ITPKA inositol-trisphosphate 3-kinase A
KRT6A keratin 6A, type II
LMNB1 lamin B1
LOC100286895 cell division cycle 27 homolog pseudogene
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LYRM9 LYR motif containing 9
MDFI MyoD family inhibitor
MEGF8 multiple EGF-like-domains 8
MGP matrix Gla protein
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBEAL2 neurobeachin-like 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUP62CL nucleoporin 62kDa C-terminal like
OSMR oncostatin M receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
POM121 POM121 transmembrane nucleoporin
PROX1 prospero homeobox 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF126P1 ring finger protein 126 pseudogene 1
RWDD2A RWD domain containing 2A
SAMD9 sterile alpha motif domain containing 9
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCIN scinderin
SEPP1 selenoprotein P, plasma, 1
SETD8 SET domain containing (lysine methyltransferase) 8
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC12A8 solute carrier family 12, member 8
SPEG SPEG complex locus
STARD5 StAR-related lipid transfer (START) domain containing 5
TH tyrosine hydroxylase
THOP1 thimet oligopeptidase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM2 transmembrane protein 2
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VASH1 vasohibin 1
ZFHX3 zinc finger homeobox 3
ZNF222 zinc finger protein 222
ZNF334 zinc finger protein 334
ZNF343 zinc finger protein 343
ZNF415 zinc finger protein 415
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768