notch Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

235 genes co-occuring with the biological term notch in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ADAM10 ADAM metallopeptidase domain 10
ADAM12 ADAM metallopeptidase domain 12
ADAM17 ADAM metallopeptidase domain 17
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT1 angiopoietin 1
APC adenomatous polyposis coli
APH1A APH1A gamma secretase subunit
APP amyloid beta (A4) precursor protein
AR androgen receptor
ASB2 ankyrin repeat and SOCS box containing 2
ASCL1 achaete-scute family bHLH transcription factor 1
ATXN1 ataxin 1
ATXN1L ataxin 1-like
BACE1 beta-site APP-cleaving enzyme 1
BATF basic leucine zipper transcription factor, ATF-like
BCL2L1 BCL2-like 1
BHLHE41 basic helix-loop-helix family, member e41
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
CC2D1A coiled-coil and C2 domain containing 1A
CC2D1B coiled-coil and C2 domain containing 1B
CCND1 cyclin D1
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD46 CD46 molecule, complement regulatory protein
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHSY1 chondroitin sulfate synthase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLN3 ceroid-lipofuscinosis, neuronal 3
CNN2 calponin 2
CNTN1 contactin 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
CRTC1 CREB regulated transcription coactivator 1
CRTC2 CREB regulated transcription coactivator 2
CTBP1 C-terminal binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DHH desert hedgehog
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DLL3 delta-like 3 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DMXL2 Dmx-like 2
DSG4 desmoglein 4
DTX1 deltex 1, E3 ubiquitin ligase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EBF1 early B-cell factor 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFR epidermal growth factor receptor
EIF3F eukaryotic translation initiation factor 3, subunit F
EP300 E1A binding protein p300
EPHB2 EPH receptor B2
EPHB4 EPH receptor B4
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
FAM172A family with sequence similarity 172, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF10 fibroblast growth factor 10
FLT4 fms-related tyrosine kinase 4
FOLR1 folate receptor 1 (adult)
FOXA1 forkhead box A1
FOXJ1 forkhead box J1
FOXP3 forkhead box P3
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GATA3 GATA binding protein 3
GIMAP5 GTPase, IMAP family member 5
GLI1 GLI family zinc finger 1
GPER1 G protein-coupled estrogen receptor 1
GREM1 gremlin 1, DAN family BMP antagonist
HBEGF heparin-binding EGF-like growth factor
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDE insulin-degrading enzyme
IFNG interferon, gamma
IHH indian hedgehog
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15 interleukin 15
IL1B interleukin 1, beta
IL33 interleukin 33
IL3RA interleukin 3 receptor, alpha (low affinity)
IL6 interleukin 6
IRF6 interferon regulatory factor 6
ITCH itchy E3 ubiquitin protein ligase
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA6 integrin, alpha 6
ITGA9 integrin, alpha 9
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAG1 jagged 1
JAG2 jagged 2
JAK3 Janus kinase 3
JUN jun proto-oncogene
KAT8 K(lysine) acetyltransferase 8
KLF4 Kruppel-like factor 4 (gut)
KLHL6 kelch-like family member 6
LEP leptin
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LRP1 low density lipoprotein receptor-related protein 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAML1 mastermind-like 1 (Drosophila)
MAML2 mastermind-like 2 (Drosophila)
MAML3 mastermind-like 3 (Drosophila)
MAP2 microtubule-associated protein 2
MCL1 myeloid cell leukemia 1
MEF2C myocyte enhancer factor 2C
MET MET proto-oncogene, receptor tyrosine kinase
MFAP5 microfibrillar associated protein 5
MGP matrix Gla protein
MIB1 mindbomb E3 ubiquitin protein ligase 1
MIB2 mindbomb E3 ubiquitin protein ligase 2
MIR181A2 microRNA 181a-2
MIR1909 microRNA 1909
MIR1915 microRNA 1915
MIR199B microRNA 199b
MIR200C microRNA 200c
MIR210 microRNA 210
MIR31 microRNA 31
MIR326 microRNA 326
MIR33A microRNA 33a
MIR34A microRNA 34a
MIR449A microRNA 449a
MITF microphthalmia-associated transcription factor
MMP1 matrix metallopeptidase 1
MSI1 musashi RNA-binding protein 1
MSX2 msh homeobox 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC16 mucin 16, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCSTN nicastrin
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFX1 nuclear transcription factor, X-box binding 1
NKAP NFKB activating protein
NODAL nodal growth differentiation factor
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NOV nephroblastoma overexpressed
NOX4 NADPH oxidase 4
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUMB numb homolog (Drosophila)
OCIAD2 OCIA domain containing 2
PCGF2 polycomb group ring finger 2
PDGFA platelet-derived growth factor alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
POFUT1 protein O-fucosyltransferase 1
POGLUT1 protein O-glucosyltransferase 1
POU3F2 POU class 3 homeobox 2
PROM1 prominin 1
PROX1 prospero homeobox 1
PSEN1 presenilin 1
PSEN2 presenilin 2
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTF1A pancreas specific transcription factor, 1a
PTHLH parathyroid hormone-like hormone
PVALB parvalbumin
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RER1 retention in endoplasmic reticulum sorting receptor 1
RHOA ras homolog family member A
RLN1 relaxin 1
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
S100A4 S100 calcium binding protein A4
SBNO1 strawberry notch homolog 1 (Drosophila)
SDC2 syndecan 2
SDCBP syndecan binding protein (syntenin)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEPT4 septin 4
SHH sonic hedgehog
SIM2 single-minded family bHLH transcription factor 2
SIRT1 sirtuin 1
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPEN spen family transcriptional repressor
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYNJ2BP synaptojanin 2 binding protein
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAL1 T-cell acute lymphocytic leukemia 1
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEK TEK tyrosine kinase, endothelial
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS2 thrombospondin 2
TMEM8B transmembrane protein 8B
TNF tumor necrosis factor
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TP63 tumor protein p63
TRA T cell receptor alpha locus
TRB T cell receptor beta locus
TRIB3 tribbles pseudokinase 3
TUBB2A tubulin, beta 2A class IIa
USP12 ubiquitin specific peptidase 12
VEGFA vascular endothelial growth factor A
VIM vimentin
WNT1 wingless-type MMTV integration site family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
WNT2B wingless-type MMTV integration site family, member 2B
WNT3A wingless-type MMTV integration site family, member 3A
YY1 YY1 transcription factor
ZEB1 zinc finger E-box binding homeobox 1