nocodazole-621 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the nocodazole-621 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABHD5 abhydrolase domain containing 5
ACOX1 acyl-CoA oxidase 1, palmitoyl
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
AREG amphiregulin
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARTN artemin
ASCC1 activating signal cointegrator 1 complex subunit 1
ASXL1 additional sex combs like transcriptional regulator 1
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
ATRX alpha thalassemia/mental retardation syndrome X-linked
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAV3 caveolin 3
CCNT1 cyclin T1
COMMD4 COMM domain containing 4
COX5B cytochrome c oxidase subunit Vb
CRCP CGRP receptor component
CSNK1E casein kinase 1, epsilon
CTTN cortactin
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDIT3 DNA-damage-inducible transcript 3
DMWD dystrophia myotonica, WD repeat containing
DUSP1 dual specificity phosphatase 1
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EIF4A1 eukaryotic translation initiation factor 4A1
EPPK1 epiplakin 1
EXTL3 exostosin-like glycosyltransferase 3
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOSL2 FOS-like antigen 2
FOXC1 forkhead box C1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GRK6 G protein-coupled receptor kinase 6
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GTPBP2 GTP binding protein 2
HABP4 hyaluronan binding protein 4
HINFP histone H4 transcription factor
HP1BP3 heterochromatin protein 1, binding protein 3
KLHL24 kelch-like family member 24
LIN7C lin-7 homolog C (C. elegans)
LRRC42 leucine rich repeat containing 42
LYPD1 LY6/PLAUR domain containing 1
MAST2 microtubule associated serine/threonine kinase 2
MSH3 mutS homolog 3
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MVP major vault protein
NDE1 nudE neurodevelopment protein 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
OSGIN1 oxidative stress induced growth inhibitor 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCSK7 proprotein convertase subtilisin/kexin type 7
PDLIM4 PDZ and LIM domain 4
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLXNA1 plexin A1
POTEKP POTE ankyrin domain family, member K, pseudogene
PPCS phosphopantothenoylcysteine synthetase
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
RANBP10 RAN binding protein 10
RARA retinoic acid receptor, alpha
RBBP5 retinoblastoma binding protein 5
RCAN1 regulator of calcineurin 1
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RPS11 ribosomal protein S11
RPS17P5 ribosomal protein S17 pseudogene 5
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEC24A SEC24 family member A
SF1 splicing factor 1
SIDT2 SID1 transmembrane family, member 2
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D15 TBC1 domain family, member 15
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFB2 transforming growth factor, beta 2
TMEM80 transmembrane protein 80
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRD T cell receptor delta locus
TSC22D4 TSC22 domain family, member 4
UBL3 ubiquitin-like 3
UBQLN4 ubiquilin 4
URI1 URI1, prefoldin-like chaperone
USF2 upstream transcription factor 2, c-fos interacting
USP15 ubiquitin specific peptidase 15
VWA1 von Willebrand factor A domain containing 1
WDR46 WD repeat domain 46
WDTC1 WD and tetratricopeptide repeats 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB40 zinc finger and BTB domain containing 40
ZC3H7B zinc finger CCCH-type containing 7B
ZFYVE9 zinc finger, FYVE domain containing 9
ZMAT5 zinc finger, matrin-type 5
ZNF124 zinc finger protein 124
ZNF335 zinc finger protein 335
ZNF576 zinc finger protein 576
ZNF652 zinc finger protein 652
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADCY6 adenylate cyclase 6
AGBL5 ATP/GTP binding protein-like 5
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANXA2P2 annexin A2 pseudogene 2
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARL4A ADP-ribosylation factor-like 4A
ARMC6 armadillo repeat containing 6
ASB6 ankyrin repeat and SOCS box containing 6
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ATG2A autophagy related 2A
ATOX1 antioxidant 1 copper chaperone
BRD7 bromodomain containing 7
C1ORF106 chromosome 1 open reading frame 106
C2ORF49 chromosome 2 open reading frame 49
C5ORF30 chromosome 5 open reading frame 30
CCBL2 cysteine conjugate-beta lyase 2
CCDC9 coiled-coil domain containing 9
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CDC7 cell division cycle 7
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP70 centrosomal protein 70kDa
CGREF1 cell growth regulator with EF-hand domain 1
CIC capicua transcriptional repressor
CLEC16A C-type lectin domain family 16, member A
CRYL1 crystallin, lambda 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHRS1 dehydrogenase/reductase (SDR family) member 1
DMTF1 cyclin D binding myb-like transcription factor 1
DPH2 DPH2 homolog (S. cerevisiae)
DRD5 dopamine receptor D5
ECD ecdysoneless homolog (Drosophila)
ECI2 enoyl-CoA delta isomerase 2
EPM2AIP1 EPM2A (laforin) interacting protein 1
EPN3 epsin 3
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUZ fuzzy planar cell polarity protein
FZD2 frizzled class receptor 2
GAS8 growth arrest-specific 8
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HIST1H1C histone cluster 1, H1c
HIST1H4J histone cluster 1, H4j
HMG20A high mobility group 20A
HOXC11 homeobox C11
IP6K1 inositol hexakisphosphate kinase 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
MB myoglobin
MCM3AP-AS1 MCM3AP antisense RNA 1
METTL21B methyltransferase like 21B
METTL22 methyltransferase like 22
MLYCD malonyl-CoA decarboxylase
MSH2 mutS homolog 2
MTMR6 myotubularin related protein 6
NCOA4 nuclear receptor coactivator 4
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NMB neuromedin B
NOL6 nucleolar protein 6 (RNA-associated)
NPPA natriuretic peptide A
NPY1R neuropeptide Y receptor Y1
NRSN2 neurensin 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PCBP4 poly(rC) binding protein 4
PEPD peptidase D
PMPCB peptidase (mitochondrial processing) beta
PNPLA6 patatin-like phospholipase domain containing 6
PPP1R26 protein phosphatase 1, regulatory subunit 26
PRMT7 protein arginine methyltransferase 7
RAB4B RAB4B, member RAS oncogene family
RBM14 RNA binding motif protein 14
RBM15B RNA binding motif protein 15B
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RIC8B RIC8 guanine nucleotide exchange factor B
RNF111 ring finger protein 111
SCML2 sex comb on midleg-like 2 (Drosophila)
SCPEP1 serine carboxypeptidase 1
SESN1 sestrin 1
SHROOM2 shroom family member 2
SLBP stem-loop binding protein
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SRBD1 S1 RNA binding domain 1
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TARBP1 TAR (HIV-1) RNA binding protein 1
TLN1 talin 1
TRAPPC12 trafficking protein particle complex 12
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TUBA1A tubulin, alpha 1a
TUBB tubulin, beta class I
TUBB6 tubulin, beta 6 class V
TULP4 tubby like protein 4
WDR44 WD repeat domain 44
XAB2 XPA binding protein 2
ZFC3H1 zinc finger, C3H1-type containing
ZNF185 zinc finger protein 185 (LIM domain)
ZNF430 zinc finger protein 430