nlrp1 inflammasome complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential. (Gene Ontology, GO_0072558)
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Genes

24 proteins co-occuring with the nlrp1 inflammasome complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NLRP1 NLR family, pyrin domain containing 1 2.87452
PYDC1 PYD (pyrin domain) containing 1 2.12749
CARD17 caspase recruitment domain family, member 17 1.78517
NLRP3 NLR family, pyrin domain containing 3 1.32708
MEFV Mediterranean fever 1.10154
NLRP10 NLR family, pyrin domain containing 10 1.07917
PANX1 pannexin 1 1.01436
NLRC5 NLR family, CARD domain containing 5 0.841023
NLRP7 NLR family, pyrin domain containing 7 0.831843
CARD8 caspase recruitment domain family, member 8 0.813946
CASP5 caspase 5, apoptosis-related cysteine peptidase 0.807524
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.807065
PYCARD PYD and CARD domain containing 0.749999
NOD2 nucleotide-binding oligomerization domain containing 2 0.60444
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.597697
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.571329
NLRX1 NLR family member X1 0.558042
IL1B interleukin 1, beta 0.551425
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.54194
NLRC4 NLR family, CARD domain containing 4 0.496205
KLK7 kallikrein-related peptidase 7 0.494585
AIM2 absent in melanoma 2 0.472813
NOD1 nucleotide-binding oligomerization domain containing 1 0.392388
ATN1 atrophin 1 0.329837