nlrp1 inflammasome complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential. (Gene Ontology, GO_0072558)
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Genes

4 proteins localized to the nlrp1 inflammasome complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PYCARD PYD and CARD domain containing 0.663342
NLRP1 NLR family, pyrin domain containing 1 0.663342
CASP5 caspase 5, apoptosis-related cysteine peptidase 0.663342
CARD17 caspase recruitment domain family, member 17 0.663342