niridazole-3301 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the niridazole-3301 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM11 ADAM metallopeptidase domain 11
ADGRA2 adhesion G protein-coupled receptor A2
AKAP7 A kinase (PRKA) anchor protein 7
ANKLE2 ankyrin repeat and LEM domain containing 2
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APOE apolipoprotein E
AQP3 aquaporin 3 (Gill blood group)
ARTN artemin
BCL2L2 BCL2-like 2
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CA9 carbonic anhydrase IX
CD8A CD8a molecule
CDC42 cell division cycle 42
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CUZD1 CUB and zona pellucida-like domains 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
FAXDC2 fatty acid hydroxylase domain containing 2
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGFR1OP FGFR1 oncogene partner
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLUD2 glutamate dehydrogenase 2
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOLGA8A golgin A8 family, member A
GSAP gamma-secretase activating protein
HFE hemochromatosis
HIST1H3E histone cluster 1, H3e
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL23A interleukin 23, alpha subunit p19
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KRT17 keratin 17, type I
KRTAP2-4 keratin associated protein 2-4
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LINC00341 long intergenic non-protein coding RNA 341
LOC647070 uncharacterized LOC647070
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MARK2 MAP/microtubule affinity-regulating kinase 2
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED16 mediator complex subunit 16
MFAP3L microfibrillar-associated protein 3-like
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMRN2 multimerin 2
MOG myelin oligodendrocyte glycoprotein
MR1 major histocompatibility complex, class I-related
MYOZ3 myozenin 3
NDE1 nudE neurodevelopment protein 1
NDRG2 NDRG family member 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUP214 nucleoporin 214kDa
OLFML2A olfactomedin-like 2A
ORAI2 ORAI calcium release-activated calcium modulator 2
PADI3 peptidyl arginine deiminase, type III
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PCDHB6 protocadherin beta 6
PCDHGA1 protocadherin gamma subfamily A, 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PEX5L peroxisomal biogenesis factor 5-like
PGAM2 phosphoglycerate mutase 2 (muscle)
PMCH pro-melanin-concentrating hormone
PML promyelocytic leukemia
PQLC2 PQ loop repeat containing 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD23B RAD23 homolog B (S. cerevisiae)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RB1 retinoblastoma 1
RHBDD3 rhomboid domain containing 3
SLC35E2 solute carrier family 35, member E2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPATA5L1 spermatogenesis associated 5-like 1
SRSF7 serine/arginine-rich splicing factor 7
STOM stomatin
SZT2 seizure threshold 2 homolog (mouse)
TAPBP TAP binding protein (tapasin)
TARP TCR gamma alternate reading frame protein
TIMP3 TIMP metallopeptidase inhibitor 3
TM4SF1 transmembrane 4 L six family member 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAK1 trafficking protein, kinesin binding 1
TRIB2 tribbles pseudokinase 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VEGFA vascular endothelial growth factor A
VIPR1 vasoactive intestinal peptide receptor 1
VWA5A von Willebrand factor A domain containing 5A
WDFY3 WD repeat and FYVE domain containing 3
WDTC1 WD and tetratricopeptide repeats 1
WSCD1 WSC domain containing 1
YIPF4 Yip1 domain family, member 4
ZFP64 ZFP64 zinc finger protein
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
AFAP1 actin filament associated protein 1
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARMC4 armadillo repeat containing 4
ARRB2 arrestin, beta 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BBC3 BCL2 binding component 3
BCL9 B-cell CLL/lymphoma 9
C1ORF105 chromosome 1 open reading frame 105
C8ORF44 chromosome 8 open reading frame 44
CA5BP1 carbonic anhydrase VB pseudogene 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDK18 cyclin-dependent kinase 18
CDKN2AIP CDKN2A interacting protein
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEB cell death-inducing DFFA-like effector b
CLCF1 cardiotrophin-like cytokine factor 1
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
DIXDC1 DIX domain containing 1
DPY19L1P1 DPY19L1 pseudogene 1
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM188A family with sequence similarity 188, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLCN folliculin
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HIST1H2AI histone cluster 1, H2ai
HIST1H2BO histone cluster 1, H2bo
HMG20A high mobility group 20A
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HPN hepsin
IFT140 intraflagellar transport 140
IFT22 intraflagellar transport 22
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
INPPL1 inositol polyphosphate phosphatase-like 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCTD7 potassium channel tetramerization domain containing 7
LAMA3 laminin, alpha 3
LIN7B lin-7 homolog B (C. elegans)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LTC4S leukotriene C4 synthase
LZTR1 leucine-zipper-like transcription regulator 1
MAP6D1 MAP6 domain containing 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MTCP1 mature T-cell proliferation 1
NARFL nuclear prelamin A recognition factor-like
NEK11 NIMA-related kinase 11
NPIPB3 nuclear pore complex interacting protein family, member B3
NPTX1 neuronal pentraxin I
NT5E 5'-nucleotidase, ecto (CD73)
NUP62CL nucleoporin 62kDa C-terminal like
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAD51B RAD51 paralog B
RIN2 Ras and Rab interactor 2
RLN1 relaxin 1
RNF170 ring finger protein 170
SECISBP2 SECIS binding protein 2
SETD1A SET domain containing 1A
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMIM14 small integral membrane protein 14
SOWAHC sosondowah ankyrin repeat domain family member C
STAB2 stabilin 2
STARD13 StAR-related lipid transfer (START) domain containing 13
STX1A syntaxin 1A (brain)
TEP1 telomerase-associated protein 1
TH tyrosine hydroxylase
TLN1 talin 1
TPCN1 two pore segment channel 1
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRNAU1AP tRNA selenocysteine 1 associated protein 1
UBTD1 ubiquitin domain containing 1
VGF VGF nerve growth factor inducible
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF160 zinc finger protein 160
ZNF365 zinc finger protein 365
ZNF394 zinc finger protein 394
ZNF516 zinc finger protein 516
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747
ZNF816 zinc finger protein 816