nf-kappab complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression. (Gene Ontology, GO_0071159)
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91 proteins co-occuring with the nf-kappab complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.92995
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.83543
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.56674
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.4125
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 1.18594
TNF tumor necrosis factor 1.1046
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.04331
IL1B interleukin 1, beta 0.912511
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.780497
TNK1 tyrosine kinase, non-receptor, 1 0.75317
ANK1 ankyrin 1, erythrocytic 0.71457
JUN jun proto-oncogene 0.683771
FGF16 fibroblast growth factor 16 0.673762
BCL3 B-cell CLL/lymphoma 3 0.629465
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.599802
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.563432
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.521841
IL10 interleukin 10 0.513677
CEP104 centrosomal protein 104kDa 0.500258
CD40 CD40 molecule, TNF receptor superfamily member 5 0.491348
IRF1 interferon regulatory factor 1 0.483676
CXCL8 chemokine (C-X-C motif) ligand 8 0.441708
TRAF3 TNF receptor-associated factor 3 0.438146
FGL2 fibrinogen-like 2 0.43617
TRAF1 TNF receptor-associated factor 1 0.433012
ICAM1 intercellular adhesion molecule 1 0.432618
FOS FBJ murine osteosarcoma viral oncogene homolog 0.422389
BIRC3 baculoviral IAP repeat containing 3 0.395098
CARD11 caspase recruitment domain family, member 11 0.392775
BLK BLK proto-oncogene, Src family tyrosine kinase 0.386208
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.373516
SLAMF1 signaling lymphocytic activation molecule family member 1 0.363185
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.343799
TRAF4 TNF receptor-associated factor 4 0.307004
MAPK3 mitogen-activated protein kinase 3 0.305143
BCL2A1 BCL2-related protein A1 0.304771
SH2B3 SH2B adaptor protein 3 0.300682
IL6 interleukin 6 0.29623
BCL2L1 BCL2-like 1 0.285507
IL1A interleukin 1, alpha 0.284769
BTG2 BTG family, member 2 0.266042
JUND jun D proto-oncogene 0.260566
PLK3 polo-like kinase 3 0.256561
AKR1C1 aldo-keto reductase family 1, member C1 0.255834
TCL1A T-cell leukemia/lymphoma 1A 0.228108
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.228108
ASL argininosuccinate lyase 0.223497
CSF1R colony stimulating factor 1 receptor 0.219265
HDAC3 histone deacetylase 3 0.216111
PTGIS prostaglandin I2 (prostacyclin) synthase 0.215063
CCND1 cyclin D1 0.214366
IFI16 interferon, gamma-inducible protein 16 0.214017
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.213322
ECI1 enoyl-CoA delta isomerase 1 0.212974
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.208481
CD40LG CD40 ligand 0.199993
CD70 CD70 molecule 0.196999
SELE selectin E 0.18859
ALCAM activated leukocyte cell adhesion molecule 0.185777
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.183935
IFNB1 interferon, beta 1, fibroblast 0.181823
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.180339
SLURP1 secreted LY6/PLAUR domain containing 1 0.175745
TRAF2 TNF receptor-associated factor 2 0.174911
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.174635
ACOT1 acyl-CoA thioesterase 1 0.170629
CDKN2A cyclin-dependent kinase inhibitor 2A 0.164315
TGM4 transglutaminase 4 0.16342
IL2 interleukin 2 0.16233
NDRG1 N-myc downstream regulated 1 0.160658
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.158692
CTF1 cardiotrophin 1 0.158129
TFF3 trefoil factor 3 (intestinal) 0.157578
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 0.156863
ATF2 activating transcription factor 2 0.142418
MALT1 MALT1 paracaspase 0.14168
PTN pleiotrophin 0.140922
MYLK3 myosin light chain kinase 3 0.140889
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.140597
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.14058
ADRB1 adrenoceptor beta 1 0.140545
TSHR thyroid stimulating hormone receptor 0.140012
PRLR prolactin receptor 0.1396
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.138648
CSN2 casein beta 0.138517
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.138397
BIRC2 baculoviral IAP repeat containing 2 0.137934
CD86 CD86 molecule 0.137869
CTSA cathepsin A 0.137164
TLR4 toll-like receptor 4 0.136135
TGFB1 transforming growth factor, beta 1 0.135863