neuropathy Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A nervous system disease that is located_in nerves or nerve cells. (Human Disease Ontology, DOID_870)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:870
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Genes

124 genes associated with the disease neuropathy in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
TCF19 transcription factor 19 2.29065
MSH5 mutS homolog 5 2.23089
C2 complement component 2 2.21684
CFB complement factor B 2.19492
STK19 serine/threonine kinase 19 2.19369
C6ORF10 chromosome 6 open reading frame 10 2.15968
DPCR1 diffuse panbronchiolitis critical region 1 2.11891
BTNL2 butyrophilin-like 2 2.11486
VARS2 valyl-tRNA synthetase 2, mitochondrial 2.09564
C6ORF15 chromosome 6 open reading frame 15 2.09435
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.09147
GPANK1 G patch domain and ankyrin repeats 1 2.09006
PRRC2A proline-rich coiled-coil 2A 2.08946
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.0583
HCG18 HLA complex group 18 (non-protein coding) 2.05217
NOTCH4 notch 4 2.03179
MUC22 mucin 22 2.03086
TRIM31 tripartite motif containing 31 2.03048
MUC21 mucin 21, cell surface associated 2.02172
RNF39 ring finger protein 39 1.99799
POU5F1 POU class 5 homeobox 1 1.98843
ZNRD1 zinc ribbon domain containing 1 1.98156
PSORS1C1 psoriasis susceptibility 1 candidate 1 1.97692
HCG9 HLA complex group 9 (non-protein coding) 1.95898
PSORS1C3 psoriasis susceptibility 1 candidate 3 (non-protein coding) 1.92643
MICB MHC class I polypeptide-related sequence B 1.92343
GPSM3 G-protein signaling modulator 3 1.88206
ATOH7 atonal homolog 7 (Drosophila) 0.931906
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.906545
TNIP1 TNFAIP3 interacting protein 1 0.523865
EPHA5 EPH receptor A5 0.491094
DCLK1 doublecortin-like kinase 1 0.477278
CHEK2 checkpoint kinase 2 0.477278
BCAS3 breast carcinoma amplified sequence 3 0.470241
XKR4 XK, Kell blood group complex subunit-related family, member 4 0.470006
RERE arginine-glutamic acid dipeptide (RE) repeats 0.465621
MYPN myopalladin 0.456271
RFTN1 raftlin, lipid raft linker 1 0.456271
LRP1B low density lipoprotein receptor-related protein 1B 0.452375
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.452375
PITPNA phosphatidylinositol transfer protein, alpha 0.430604
SCFD2 sec1 family domain containing 2 0.430311
FGD4 FYVE, RhoGEF and PH domain containing 4 0.426549
LIMK2 LIM domain kinase 2 0.425585
DENND2A DENN/MADD domain containing 2A 0.422054
TSHR thyroid stimulating hormone receptor 0.422054
TRIO trio Rho guanine nucleotide exchange factor 0.422054
ESRRG estrogen-related receptor gamma 0.414949
PEX14 peroxisomal biogenesis factor 14 0.414949
LOC100506023 uncharacterized LOC100506023 0.413648
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.412463
MYH9 myosin, heavy chain 9, non-muscle 0.411526
GLIS3 GLIS family zinc finger 3 0.407083
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.404129
PALLD palladin, cytoskeletal associated protein 0.404129
PTPRT protein tyrosine phosphatase, receptor type, T 0.400169
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.400012
SPIDR scaffolding protein involved in DNA repair 0.398456
TRAF3 TNF receptor-associated factor 3 0.398246
DTNBP1 dystrobrevin binding protein 1 0.39618
ERBB4 erb-b2 receptor tyrosine kinase 4 0.395619
SLCO1B1 solute carrier organic anion transporter family, member 1B1 0.393913
MISP mitotic spindle positioning 0.393061
SGCZ sarcoglycan, zeta 0.392363
PARK2 parkin RBR E3 ubiquitin protein ligase 0.39063
EPHA6 EPH receptor A6 0.390528
GSDMB gasdermin B 0.38878
TNPO3 transportin 3 0.387883
RORA RAR-related orphan receptor A 0.385072
FAM159A family with sequence similarity 159, member A 0.385072
ZPBP2 zona pellucida binding protein 2 0.380436
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 0.373818
NTF3 neurotrophin 3 0.372952
KALRN kalirin, RhoGEF kinase 0.371529
LRRK2 leucine-rich repeat kinase 2 0.368877
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.368877
MEGF11 multiple EGF-like-domains 11 0.365609
ZNF667 zinc finger protein 667 0.364167
CORO1C coronin, actin binding protein, 1C 0.361581
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.361581
PLCL1 phospholipase C-like 1 0.361581
NUF2 NUF2, NDC80 kinetochore complex component 0.360411
NKAIN3 Na+/K+ transporting ATPase interacting 3 0.359312
MTSS1 metastasis suppressor 1 0.359312
IVD isovaleryl-CoA dehydrogenase 0.358275
MAMLD1 mastermind-like domain containing 1 0.358275
ROR1 receptor tyrosine kinase-like orphan receptor 1 0.357293
ANK1 ankyrin 1, erythrocytic 0.357293
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 0.353425
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.353425
RSBN1 round spermatid basic protein 1 0.351733
BARX2 BARX homeobox 2 0.350937
ADCY5 adenylate cyclase 5 0.350171
STARD3 StAR-related lipid transfer (START) domain containing 3 0.349434
CSN1S2BP casein alpha s2-like B, pseudogene 0.349434
SLIT3 slit homolog 3 (Drosophila) 0.348723
SLC39A11 solute carrier family 39, member 11 0.348037
EDA ectodysplasin A 0.348037
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.347373
CAMKMT calmodulin-lysine N-methyltransferase 0.345505
CNTN5 contactin 5 0.345505
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.344919
IDO2 indoleamine 2,3-dioxygenase 2 0.344919
NPAS3 neuronal PAS domain protein 3 0.34435
PHTF1 putative homeodomain transcription factor 1 0.343797
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.343797
TOX thymocyte selection-associated high mobility group box 0.34326
KIAA1549 KIAA1549 0.342736
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.34163
STAT4 signal transducer and activator of transcription 4 0.34163
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.341059
NKX2-3 NK2 homeobox 3 0.340501
TBX5 T-box 5 0.340501
ANKRD55 ankyrin repeat domain 55 0.339956
PDE4D phosphodiesterase 4D, cAMP-specific 0.339956
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.339425
SCAMP5 secretory carrier membrane protein 5 0.339425
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.338905
BCL2L15 BCL2-like 15 0.338397
VAC14 Vac14 homolog (S. cerevisiae) 0.338397
INADL InaD-like (Drosophila) 0.338397
TCAP titin-cap 0.337899
CD226 CD226 molecule 0.337899
FGD5 FYVE, RhoGEF and PH domain containing 5 0.337899