neurofilament cytoskeleton Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons. (Gene Ontology, GO_0060053)
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Genes

312 proteins co-occuring with the neurofilament cytoskeleton cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NEFH neurofilament, heavy polypeptide 3.10351
NEFM neurofilament, medium polypeptide 2.90004
ENO2 enolase 2 (gamma, neuronal) 2.62166
SYP synaptophysin 2.51081
NEFL neurofilament, light polypeptide 2.14059
GFAP glial fibrillary acidic protein 2.10274
MBP myelin basic protein 2.01412
NES nestin 1.9855
MAP2 microtubule-associated protein 2 1.97132
INA internexin neuronal intermediate filament protein, alpha 1.85868
NGF nerve growth factor (beta polypeptide) 1.84019
TH tyrosine hydroxylase 1.81512
CALCA calcitonin-related polypeptide alpha 1.80373
TAC1 tachykinin, precursor 1 1.66659
B3GAT1 beta-1,3-glucuronyltransferase 1 1.65032
CALB1 calbindin 1, 28kDa 1.63182
GAN gigaxonin 1.56389
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.5367
CDK5 cyclin-dependent kinase 5 1.51976
GAP43 growth associated protein 43 1.51356
CALB2 calbindin 2 1.51356
CHGA chromogranin A 1.50961
PVALB parvalbumin 1.49267
MAPT microtubule-associated protein tau 1.48758
CHAT choline O-acetyltransferase 1.48588
DES desmin 1.39294
ACHE acetylcholinesterase (Yt blood group) 1.33413
SRRM1 serine/arginine repetitive matrix 1 1.32167
MAP1B microtubule-associated protein 1B 1.26974
NGFR nerve growth factor receptor 1.25548
NPY neuropeptide Y 1.2387
MAP4 microtubule-associated protein 4 1.23557
BDNF brain-derived neurotrophic factor 1.2288
DNM2 dynamin 2 1.22672
SST somatostatin 1.18132
NCAM1 neural cell adhesion molecule 1 1.17106
NTF3 neurotrophin 3 1.16747
GDNF glial cell derived neurotrophic factor 1.15876
FGF2 fibroblast growth factor 2 (basic) 1.13625
THY1 Thy-1 cell surface antigen 1.10409
NPS neuropeptide S 1.08374
VIP vasoactive intestinal peptide 1.07258
CD34 CD34 molecule 1.06701
S100B S100 calcium binding protein B 1.06195
SOD2 superoxide dismutase 2, mitochondrial 1.0423
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.03378
MAG myelin associated glycoprotein 1.02032
SYN1 synapsin I 0.985854
MOG myelin oligodendrocyte glycoprotein 0.942584
ASCL1 achaete-scute family bHLH transcription factor 1 0.936432
KRT20 keratin 20, type I 0.93596
CNTF ciliary neurotrophic factor 0.916243
MPZ myelin protein zero 0.899962
TUBA1A tubulin, alpha 1a 0.898109
ISL1 ISL LIM homeobox 1 0.884705
CD99 CD99 molecule 0.845155
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.845155
APP amyloid beta (A4) precursor protein 0.843778
PMP22 peripheral myelin protein 22 0.836892
ALPPL2 alkaline phosphatase, placental-like 2 0.809817
ALPL alkaline phosphatase, liver/bone/kidney 0.8089
ALPP alkaline phosphatase, placental 0.808441
CRYAB crystallin, alpha B 0.799728
EDA ectodysplasin A 0.79652
GAL galanin/GMAP prepropeptide 0.795604
HSPB1 heat shock 27kDa protein 1 0.789649
CD68 CD68 molecule 0.779583
TUB tubby bipartite transcription factor 0.774558
OLIG2 oligodendrocyte lineage transcription factor 2 0.768171
POU4F1 POU class 4 homeobox 1 0.763162
PAX6 paired box 6 0.753623
MB myoglobin 0.748189
NEUROD1 neuronal differentiation 1 0.747285
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.735565
SAG S-antigen; retina and pineal gland (arrestin) 0.730628
POMC proopiomelanocortin 0.720351
PHF1 PHD finger protein 1 0.71946
FN1 fibronectin 1 0.711908
NRCAM neuronal cell adhesion molecule 0.688576
DCX doublecortin 0.684207
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.676368
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 0.6638
F8 coagulation factor VIII, procoagulant component 0.6638
AIF1 allograft inflammatory factor 1 0.650869
RTN4 reticulon 4 0.645716
CAST calpastatin 0.641429
STMN2 stathmin 2 0.636723
GRP gastrin-releasing peptide 0.632024
MTMR2 myotubularin related protein 2 0.626057
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.614589
KRT7 keratin 7, type II 0.608241
PDYN prodynorphin 0.60655
PROS1 protein S (alpha) 0.606128
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.605284
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.604862
ATF3 activating transcription factor 3 0.600223
NEU2 sialidase 2 (cytosolic sialidase) 0.596855
PTPRC protein tyrosine phosphatase, receptor type, C 0.589714
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.588456
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.588456
TRIM2 tripartite motif containing 2 0.588037
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.588037
PNMT phenylethanolamine N-methyltransferase 0.586361
DSP desmoplakin 0.579669
GALC galactosylceramidase 0.571329
ACTB actin, beta 0.565092
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.563017
TP53 tumor protein p53 0.562602
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.555973
CSN1S1 casein alpha s1 0.54936
EWSR1 EWS RNA-binding protein 1 0.547297
NF2 neurofibromin 2 (merlin) 0.545648
SYNM synemin, intermediate filament protein 0.544823
PNPLA6 patatin-like phospholipase domain containing 6 0.544
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.543587
ACTG1 actin gamma 1 0.536183
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.532488
NTF4 neurotrophin 4 0.52675
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.525522
OPN4 opsin 4 0.523885
UBC ubiquitin C 0.523476
NF1 neurofibromin 1 0.523067
FOS FBJ murine osteosarcoma viral oncogene homolog 0.5149
RHO rhodopsin 0.509197
CAPN2 calpain 2, (m/II) large subunit 0.50879
HBA1 hemoglobin, alpha 1 0.505131
PRX periaxin 0.504318
GMFB glia maturation factor, beta 0.503099
HBA2 hemoglobin, alpha 2 0.499447
RPS27A ribosomal protein S27a 0.499042
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.499042
RCVRN recoverin 0.498231
UBB ubiquitin B 0.483273
CST3 cystatin C 0.479245
IGF1 insulin-like growth factor 1 (somatomedin C) 0.476429
JUN jun proto-oncogene 0.47442
GLUL glutamate-ammonia ligase 0.472813
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.466399
AFP alpha-fetoprotein 0.465198
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.463198
ALB albumin 0.458404
KIF5A kinesin family member 5A 0.446862
CAPN1 calpain 1, (mu/I) large subunit 0.446465
CEND1 cell cycle exit and neuronal differentiation 1 0.444482
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.438146
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 0.43538
SCN10A sodium channel, voltage gated, type X alpha subunit 0.434196
RGMA repulsive guidance molecule family member a 0.430253
VIM vimentin 0.429072
MLANA melan-A 0.421997
SOX10 SRY (sex determining region Y)-box 10 0.41886
SHH sonic hedgehog 0.418077
MNX1 motor neuron and pancreas homeobox 1 0.417294
KRT8 keratin 8, type II 0.41182
INS insulin 0.40675
SPRED1 sprouty-related, EVH1 domain containing 1 0.393936
POU4F2 POU class 4 homeobox 2 0.392388
AQP4 aquaporin 4 0.378507
MYOG myogenin (myogenic factor 4) 0.376586
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.372749
MRAP melanocortin 2 receptor accessory protein 0.372749
NRN1 neuritin 1 0.371216
RTN4R reticulon 4 receptor 0.370067
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.367006
GJB1 gap junction protein, beta 1, 32kDa 0.366241
APOE apolipoprotein E 0.365859
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.365477
PHOX2A paired-like homeobox 2a 0.364331
NEUROG1 neurogenin 1 0.361277
COX5A cytochrome c oxidase subunit Va 0.360896
GLB1 galactosidase, beta 1 0.360896
PPY pancreatic polypeptide 0.353282
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.349105
SDF4 stromal cell derived factor 4 0.347967
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.345692
CLDN1 claudin 1 0.341907
DLX2 distal-less homeobox 2 0.341907
KRT18 keratin 18, type I 0.341907
EGR2 early growth response 2 0.339639
CLDN7 claudin 7 0.337751
PCNA proliferating cell nuclear antigen 0.337373
DCTN1 dynactin 1 0.336996
ASMT acetylserotonin O-methyltransferase 0.336619
DNTT DNA nucleotidylexotransferase 0.335487
TNC tenascin C 0.333225
CNTN2 contactin 2 (axonal) 0.327956
TARDBP TAR DNA binding protein 0.326453
GJB6 gap junction protein, beta 6, 30kDa 0.324201
DCAF8 DDB1 and CUL4 associated factor 8 0.320077
HSPA4 heat shock 70kDa protein 4 0.320077
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.318953
SOX2 SRY (sex determining region Y)-box 2 0.316334
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.316334
NTS neurotensin 0.315586
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.314839
TSPO translocator protein (18kDa) 0.310358
TRGJP2 T cell receptor gamma joining P2 0.309613
ABHD17A abhydrolase domain containing 17A 0.309613
ABHD17AP1 abhydrolase domain containing 17A pseudogene 1 0.309613
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.308494
GSK3A glycogen synthase kinase 3 alpha 0.306632
GSK3B glycogen synthase kinase 3 beta 0.304399
CCK cholecystokinin 0.303283
KIF1B kinesin family member 1B 0.302168
SMN2 survival of motor neuron 2, centromeric 0.298826
BHLHE23 basic helix-loop-helix family, member e23 0.292157
KERA keratocan 0.288829
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.288091
GAST gastrin 0.280716
HSPA12A heat shock 70kDa protein 12A 0.275569
NEUROG2 neurogenin 2 0.272633
DST dystonin 0.271533
MAPK8 mitogen-activated protein kinase 8 0.267505
PROM1 prominin 1 0.266042
LYZ lysozyme 0.264581
TPH1 tryptophan hydroxylase 1 0.264215
GJA1 gap junction protein, alpha 1, 43kDa 0.26312
FGF1 fibroblast growth factor 1 (acidic) 0.26312
GCG glucagon 0.259473
S100P S100 calcium binding protein P 0.258016
PSEN1 presenilin 1 0.258016
NPY1R neuropeptide Y receptor Y1 0.257652
CXCL13 chemokine (C-X-C motif) ligand 13 0.256561
CDK4 cyclin-dependent kinase 4 0.256197
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 0.255107
NECAB1 N-terminal EF-hand calcium binding protein 1 0.252927
PRNP prion protein 0.249664
GLG1 golgi glycoprotein 1 0.248578
SBF2 SET binding factor 2 0.248216
CD44 CD44 molecule (Indian blood group) 0.247492
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.247492
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.24713
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.246769
RET ret proto-oncogene 0.245685
EFNA4 ephrin-A4 0.245323
SLC16A12 solute carrier family 16, member 12 0.239197
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.237401
FUS FUS RNA binding protein 0.237042
MMD monocyte to macrophage differentiation-associated 0.233817
MYOD1 myogenic differentiation 1 0.232029
TTR transthyretin 0.229888
NRBP2 nuclear receptor binding protein 2 0.227752
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.227041
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.222083
NCAN neurocan 0.219617
NOTCH1 notch 1 0.218914
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 0.218563
SCN3A sodium channel, voltage gated, type III alpha subunit 0.217861
NAV2 neuron navigator 2 0.217511
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.217511
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 0.214017
AANAT aralkylamine N-acetyltransferase 0.213669
GDAP1 ganglioside induced differentiation associated protein 1 0.213322
DPYSL3 dihydropyrimidinase-like 3 0.212627
NOG noggin 0.208825
EGFR epidermal growth factor receptor 0.207451
CA4 carbonic anhydrase IV 0.207451
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.203361
PAX3 paired box 3 0.200999
PLP1 proteolipid protein 1 0.197993
TACR1 tachykinin receptor 1 0.195681
IL6 interleukin 6 0.193719
ITGAD integrin, alpha D 0.191777
ACPP acid phosphatase, prostate 0.190175
CDC37L1 cell division cycle 37-like 1 0.189539
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.187646
SALL3 spalt-like transcription factor 3 0.187333
CRX cone-rod homeobox 0.187333
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.186087
HSPB8 heat shock 22kDa protein 8 0.184853
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.184547
SMN1 survival of motor neuron 1, telomeric 0.184241
GNS glucosamine (N-acetyl)-6-sulfatase 0.184241
TSC2 tuberous sclerosis 2 0.182723
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.182723
PAX7 paired box 7 0.182122
FTL ferritin, light polypeptide 0.181524
FTH1 ferritin, heavy polypeptide 1 0.180045
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 0.180045
PNOC prepronociceptin 0.179459
FGFR4 fibroblast growth factor receptor 4 0.179459
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 0.176587
MUCL1 mucin-like 1 0.175745
NDNL2 necdin-like 2 0.174911
CA2 carbonic anhydrase II 0.174087
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.173003
NANOG Nanog homeobox 0.172735
OTX1 orthodenticle homeobox 1 0.172201
MKI67 marker of proliferation Ki-67 0.171937
BTG4 B-cell translocation gene 4 0.17141
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.17141
SNCAIP synuclein, alpha interacting protein 0.171149
H1F0 H1 histone family, member 0 0.167611
MAGEH1 melanoma antigen family H1 0.167611
SETX senataxin 0.167125
WNT1 wingless-type MMTV integration site family, member 1 0.166884
RLBP1 retinaldehyde binding protein 1 0.166884
CADM3 cell adhesion molecule 3 0.166643
NT5C1A 5'-nucleotidase, cytosolic IA 0.165932
DCTN5 dynactin 5 (p25) 0.165697
ASIC3 acid sensing (proton gated) ion channel 3 0.165697
SNPH syntaphilin 0.162763
TEF thyrotrophic embryonic factor 0.161905
DBN1 drebrin 1 0.161905
PTPRS protein tyrosine phosphatase, receptor type, S 0.160456
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.160053
DPYSL2 dihydropyrimidinase-like 2 0.159856
TNF tumor necrosis factor 0.159658
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.159074
TPPP3 tubulin polymerization-promoting protein family member 3 0.158315
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.158315
MMP9 matrix metallopeptidase 9 0.156342