neuroendocrine tumor Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An endocrine gland cancer that has_material_basis_in neuroendocrine cells. (Human Disease Ontology, DOID_169)
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Genes

203 genes co-occuring with the disease neuroendocrine tumor in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.90704
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 2.84298
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 2.6686
GAST gastrin 2.59902
SST somatostatin 2.54513
PRL prolactin 2.42841
MEN1 multiple endocrine neoplasia I 2.24417
CHGA chromogranin A 2.24311
SDHAF2 succinate dehydrogenase complex assembly factor 2 2.11145
PGLS 6-phosphogluconolactonase 2.10952
TMEM127 transmembrane protein 127 2.01203
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.98715
SYP synaptophysin 1.97597
ENO2 enolase 2 (gamma, neuronal) 1.93139
RET ret proto-oncogene 1.73003
PPY pancreatic polypeptide 1.70542
POMC proopiomelanocortin 1.66015
VIP vasoactive intestinal peptide 1.5476
TRH thyrotropin-releasing hormone 1.54318
CALCA calcitonin-related polypeptide alpha 1.48823
NF1 neurofibromin 1 1.4149
SSTR2 somatostatin receptor 2 1.30357
GCG glucagon 1.28479
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.18927
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.18884
GHRH growth hormone releasing hormone 1.15752
ASCL1 achaete-scute family bHLH transcription factor 1 1.11477
INS insulin 1.10132
SSTR5 somatostatin receptor 5 1.07614
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 1.07068
AIP aryl hydrocarbon receptor interacting protein 1.05723
SDHAF1 succinate dehydrogenase complex assembly factor 1 1.05303
GRP gastrin-releasing peptide 1.04462
EPAS1 endothelial PAS domain protein 1 1.00161
KLK8 kallikrein-related peptidase 8 0.984321
NCAM1 neural cell adhesion molecule 1 0.975903
CCK cholecystokinin 0.959123
DRD2 dopamine receptor D2 0.954108
SSTR1 somatostatin receptor 1 0.95369
NTS neurotensin 0.927105
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.917611
EGLN1 egl-9 family hypoxia-inducible factor 1 0.915963
C11ORF57 chromosome 11 open reading frame 57 0.89541
IGF1 insulin-like growth factor 1 (somatomedin C) 0.888029
MAX MYC associated factor X 0.867959
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.853631
ADGRF3 adhesion G protein-coupled receptor F3 0.824128
SSTR4 somatostatin receptor 4 0.814693
PTH parathyroid hormone 0.812232
SSTR3 somatostatin receptor 3 0.811001
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.792541
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.774114
ZNF367 zinc finger protein 367 0.704742
NAP1L1 nucleosome assembly protein 1-like 1 0.693098
TG thyroglobulin 0.687491
KRT20 keratin 20, type I 0.687091
CRH corticotropin releasing hormone 0.686291
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.680297
B3GAT1 beta-1,3-glucuronyltransferase 1 0.676706
SNED1 sushi, nidogen and EGF-like domains 1 0.656441
ALG9 ALG9, alpha-1,2-mannosyltransferase 0.648533
TMEM108 transmembrane protein 108 0.643009
CNTN5 contactin 5 0.637102
HRH2 histamine receptor H2 0.628457
GFAP glial fibrillary acidic protein 0.604981
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.60069
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.59991
MLANA melan-A 0.585497
SCTR secretin receptor 0.584719
PTHLH parathyroid hormone-like hormone 0.559839
CHGB chromogranin B 0.554791
TP53 tumor protein p53 0.549747
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.545868
FH fumarate hydratase 0.538506
AVP arginine vasopressin 0.536183
HIF3A hypoxia inducible factor 3, alpha subunit 0.524974
BMP4 bone morphogenetic protein 4 0.522659
KIF1B kinesin family member 1B 0.516879
KRT7 keratin 7, type II 0.50689
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 0.494266
NGF nerve growth factor (beta polypeptide) 0.487407
NPS neuropeptide S 0.468819
FGF2 fibroblast growth factor 2 (basic) 0.46466
CD34 CD34 molecule 0.456732
TRHR thyrotropin-releasing hormone receptor 0.451078
NEUROD4 neuronal differentiation 4 0.4443
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.442795
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.442042
PIH1D2 PIH1 domain containing 2 0.439786
SCG2 secretogranin II 0.42214
SMAD4 SMAD family member 4 0.418394
SMS spermine synthase 0.406798
NME6 NME/NM23 nucleoside diphosphate kinase 6 0.394118
TH tyrosine hydroxylase 0.390769
RWDD3 RWD domain containing 3 0.390025
NKX2-1 NK2 homeobox 1 0.389653
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.384451
EGLN3 egl-9 family hypoxia-inducible factor 3 0.376661
MTA1 metastasis associated 1 0.374068
ARHGAP20 Rho GTPase activating protein 20 0.372958
ESR1 estrogen receptor 1 0.371847
PDYN prodynorphin 0.368518
STC1 stanniocalcin 1 0.357446
PYGM phosphorylase, glycogen, muscle 0.35082
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.349349
MRGPRX2 MAS-related GPR, member X2 0.345675
DAXX death-domain associated protein 0.342739
PAX8 paired box 8 0.338707
TAC1 tachykinin, precursor 1 0.337608
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.337242
PTTG1 pituitary tumor-transforming 1 0.335046
HRAS Harvey rat sarcoma viral oncogene homolog 0.330295
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 0.325916
NOTCH1 notch 1 0.320454
GHRL ghrelin/obestatin prepropeptide 0.316456
NMB neuromedin B 0.315366
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 0.313552
SSR1 signal sequence receptor, alpha 0.31029
GAL galanin/GMAP prepropeptide 0.309928
NPY neuropeptide Y 0.308118
LCK LCK proto-oncogene, Src family tyrosine kinase 0.303059
VEGFA vascular endothelial growth factor A 0.298371
PTEN phosphatase and tensin homolog 0.289027
RNF7 ring finger protein 7 0.282582
PRLR prolactin receptor 0.275089
WIF1 WNT inhibitory factor 1 0.27153
MED25 mediator complex subunit 25 0.269398
PCNA proliferating cell nuclear antigen 0.268687
ZNF197 zinc finger protein 197 0.266203
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.25877
MLN motilin 0.251015
GRPR gastrin-releasing peptide receptor 0.24715
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.238054
GNAS GNAS complex locus 0.228679
GIPR gastric inhibitory polypeptide receptor 0.225573
HN1L hematological and neurological expressed 1-like 0.224196
SCG5 secretogranin V 0.223853
NEUROD1 neuronal differentiation 1 0.215653
FGF1 fibroblast growth factor 1 (acidic) 0.202618
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.201308
CORT cortistatin 0.200982
SIK2 salt-inducible kinase 2 0.198064
CALB2 calbindin 2 0.196459
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 0.190786
FFAR1 free fatty acid receptor 1 0.189244
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.18651
SRL sarcalumenin 0.184128
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 0.183835
GLP1R glucagon-like peptide 1 receptor 0.17952
MKI67 marker of proliferation Ki-67 0.177301
CD99 CD99 molecule 0.176215
IAPP islet amyloid polypeptide 0.168381
ZNF410 zinc finger protein 410 0.166544
RB1 retinoblastoma 1 0.165874
SHBG sex hormone-binding globulin 0.162908
NMBR neuromedin B receptor 0.161139
PIDD1 p53-induced death domain protein 1 0.160021
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.160021
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 0.159124
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 0.158434
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.158097
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.141316
MGLL monoglyceride lipase 0.139129
VIPR1 vasoactive intestinal peptide receptor 1 0.138681
PCSK6 proprotein convertase subtilisin/kexin type 6 0.138332
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.137046
FMN2 formin 2 0.135879
PAM peptidylglycine alpha-amidating monooxygenase 0.135182
AKAP5 A kinase (PRKA) anchor protein 5 0.133545
JUND jun D proto-oncogene 0.133253
DLAT dihydrolipoamide S-acetyltransferase 0.133059
FBN2 fibrillin 2 0.132751
CS citrate synthase 0.132481
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 0.132253
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 0.132237
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.132137
PRNT prion protein (testis specific) 0.13212
HSPB2 heat shock 27kDa protein 2 0.131833
BBS2 Bardet-Biedl syndrome 2 0.131502
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 0.131288
FAAH fatty acid amide hydrolase 0.131031
DAAM1 dishevelled associated activator of morphogenesis 1 0.130995
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.13075
CTCF CCCTC-binding factor (zinc finger protein) 0.130519
ARID4A AT rich interactive domain 4A (RBP1-like) 0.130064
SLIT3 slit homolog 3 (Drosophila) 0.130044
KDM6B lysine (K)-specific demethylase 6B 0.127329
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.126919
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.126173
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.125924
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.125728
FAXDC2 fatty acid hydroxylase domain containing 2 0.124916
SPTA1 spectrin, alpha, erythrocytic 1 0.124493
SPTBN2 spectrin, beta, non-erythrocytic 2 0.123057
DPP7 dipeptidyl-peptidase 7 0.122956
RARB retinoic acid receptor, beta 0.122754
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.122653
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.121635
FURIN furin (paired basic amino acid cleaving enzyme) 0.121635
MPG N-methylpurine-DNA glycosylase 0.120864
POU2AF1 POU class 2 associating factor 1 0.12037
KRT19 keratin 19, type I 0.118484
REN renin 0.117716