neural tube closure Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. (Gene Ontology, GO_0001843)
External Link http://amigo.geneontology.org/amigo/term/GO:0001843
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Genes

76 genes participating in the neural tube closure biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADM adrenomedullin
ALX1 ALX homeobox 1
APAF1 apoptotic peptidase activating factor 1
ARHGAP35 Rho GTPase activating protein 35
ARID1A AT rich interactive domain 1A (SWI-like)
BBS4 Bardet-Biedl syndrome 4
BCL10 B-cell CLL/lymphoma 10
BMP4 bone morphogenetic protein 4
CECR2 cat eye syndrome chromosome region, candidate 2
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
COBL cordon-bleu WH2 repeat protein
DEAF1 DEAF1 transcription factor
DLC1 DLC1 Rho GTPase activating protein
DVL2 dishevelled segment polarity protein 2
ENAH enabled homolog (Drosophila)
FUZ fuzzy planar cell polarity protein
FZD3 frizzled class receptor 3
FZD6 frizzled class receptor 6
GLMN glomulin, FKBP associated protein
GRHL2 grainyhead-like 2 (Drosophila)
GRHL3 grainyhead-like 3 (Drosophila)
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
IFT122 intraflagellar transport 122
IFT172 intraflagellar transport 172
IFT57 intraflagellar transport 57
KAT2A K(lysine) acetyltransferase 2A
KDM6A lysine (K)-specific demethylase 6A
KIF20B kinesin family member 20B
LHX2 LIM homeobox 2
LIAS lipoic acid synthetase
LMO4 LIM domain only 4
LRP6 low density lipoprotein receptor-related protein 6
MED12 mediator complex subunit 12
NCKAP1 NCK-associated protein 1
NOG noggin
OPA1 optic atrophy 1 (autosomal dominant)
PAX2 paired box 2
PAX3 paired box 3
PFN1 profilin 1
PHACTR4 phosphatase and actin regulator 4
PLXNB2 plexin B2
PRICKLE1 prickle homolog 1 (Drosophila)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTCH1 patched 1
PTK7 protein tyrosine kinase 7 (inactive)
RARA retinoic acid receptor, alpha
RARG retinoic acid receptor, gamma
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SALL1 spalt-like transcription factor 1
SALL4 spalt-like transcription factor 4
SCRIB scribbled planar cell polarity protein
SEC24B SEC24 family member B
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD2 SET domain containing 2
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SHROOM3 shroom family member 3
SKI SKI proto-oncogene
STIL SCL/TAL1 interrupting locus
SUFU suppressor of fused homolog (Drosophila)
T T, brachyury homolog (mouse)
TEAD2 TEA domain family member 2
TGIF1 TGFB-induced factor homeobox 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TULP3 tubby like protein 3
TWIST1 twist family bHLH transcription factor 1
VANGL2 VANGL planar cell polarity protein 2
VASP vasodilator-stimulated phosphoprotein
WNT5A wingless-type MMTV integration site family, member 5A
ZEB2 zinc finger E-box binding homeobox 2
ZIC2 Zic family member 2
ZIC5 Zic family member 5