nephropathy Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A urinary system disease that is located_in the kidney. (Human Disease Ontology, DOID_557)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0000112
Similar Terms
Downloads & Tools

Genes

70 genes associated with the nephropathy phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.9475
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.20103
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.54733
MAP3K15 mitogen-activated protein kinase kinase kinase 15 1.45857
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 1.4488
CFH complement factor H 1.40061
MYH9 myosin, heavy chain 9, non-muscle 1.38172
HORMAD2 HORMA domain containing 2 1.32793
RNF185 ring finger protein 185 1.2083
LIMK2 LIM domain kinase 2 1.19898
PDE3A phosphodiesterase 3A, cGMP-inhibited 1.14276
ENOX1 ecto-NOX disulfide-thiol exchanger 1 1.14006
LARGE like-glycosyltransferase 1.12851
CHN2 chimerin 2 1.07223
SASH1 SAM and SH3 domain containing 1 1.0674
GRIK2 glutamate receptor, ionotropic, kainate 2 1.01418
CARS cysteinyl-tRNA synthetase 0.967514
SORBS1 sorbin and SH3 domain containing 1 0.930595
ELMO1 engulfment and cell motility 1 0.868241
UNC5C unc-5 homolog C (C. elegans) 0.833415
C6ORF10 chromosome 6 open reading frame 10 0.802966
LOC100294145 uncharacterized LOC100294145 0.7965
TBC1D14 TBC1 domain family, member 14 0.776638
SMYD3 SET and MYND domain containing 3 0.769717
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.767696
PDE5A phosphodiesterase 5A, cGMP-specific 0.767696
PRRC2A proline-rich coiled-coil 2A 0.752335
FAM134B family with sequence similarity 134, member B 0.747666
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.708265
MARCH11 membrane-associated ring finger (C3HC4) 11 0.690584
NCALD neurocalcin delta 0.690584
ISM1 isthmin 1, angiogenesis inhibitor 0.672779
IL12RB1 interleukin 12 receptor, beta 1 0.670205
DNAH11 dynein, axonemal, heavy chain 11 0.669923
NTN1 netrin 1 0.66338
FGF12 fibroblast growth factor 12 0.652631
OR2L13 olfactory receptor, family 2, subfamily L, member 13 0.648884
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.647116
MYO5B myosin VB 0.635958
TMEM63C transmembrane protein 63C 0.628781
NRXN1 neurexin 1 0.628362
LOC645513 uncharacterized LOC645513 0.624663
RNF17 ring finger protein 17 0.618783
ZNF202 zinc finger protein 202 0.618783
GAP43 growth associated protein 43 0.614969
LOC284661 uncharacterized LOC284661 0.613082
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.608153
NRXN3 neurexin 3 0.607443
NEGR1 neuronal growth regulator 1 0.605515
FABP2 fatty acid binding protein 2, intestinal 0.599122
PEX7 peroxisomal biogenesis factor 7 0.581861
CERS6 ceramide synthase 6 0.577224
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.560832
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) 0.55667
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.55536
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.553442
KRT2 keratin 2, type II 0.552815
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.531556
MMS22L MMS22-like, DNA repair protein 0.511041
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.498792
SV2C synaptic vesicle glycoprotein 2C 0.496801
YPEL1 yippee-like 1 (Drosophila) 0.486163
THBS4 thrombospondin 4 0.470822
BMPR1B bone morphogenetic protein receptor, type IB 0.463909
ITGA1 integrin, alpha 1 0.450957
VWF von Willebrand factor 0.438588
COL4A1 collagen, type IV, alpha 1 0.429632
COL5A1 collagen, type V, alpha 1 0.429632
GRHL2 grainyhead-like 2 (Drosophila) 0.429005
BMP5 bone morphogenetic protein 5 0.426061