neoplasm of the nervous system Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0004375
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Genes

160 genes associated with the neoplasm of the nervous system phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
BARD1 BRCA1 associated RING domain 1 0.482788
TERT telomerase reverse transcriptase 0.472611
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.453886
CDKN2B-AS1 CDKN2B antisense RNA 1 0.430874
LMO1 LIM domain only 1 (rhombotin 1) 0.430874
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.41441
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.40959
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.39969
RTEL1 regulator of telomere elongation helicase 1 0.393646
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.382926
PHLDB1 pleckstrin homology-like domain, family B, member 1 0.380214
LRP1B low density lipoprotein receptor-related protein 1B 0.362905
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.359111
KIF26B kinesin family member 26B 0.354177
DGKI diacylglycerol kinase, iota 0.353374
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.352816
MGMT O-6-methylguanine-DNA methyltransferase 0.351631
LIN28B lin-28 homolog B (C. elegans) 0.351631
SMYD3 SET and MYND domain containing 3 0.343911
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.343479
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.339946
EGFR epidermal growth factor receptor 0.338997
DBT dihydrolipoamide branched chain transacylase E2 0.33364
RSRC1 arginine/serine-rich coiled-coil 1 0.327343
TRAF5 TNF receptor-associated factor 5 0.325387
CPZ carboxypeptidase Z 0.323259
XPO4 exportin 4 0.322898
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.322022
ACOT11 acyl-CoA thioesterase 11 0.320164
SSBP2 single-stranded DNA binding protein 2 0.318077
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.314977
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.310606
MIR205HG MIR205 host gene 0.307096
CALCOCO2 calcium binding and coiled-coil domain 2 0.303335
IL31RA interleukin 31 receptor A 0.301475
KAZN kazrin, periplakin interacting protein 0.301475
DNAH7 dynein, axonemal, heavy chain 7 0.301365
LRRC69 leucine rich repeat containing 69 0.300463
TIAM1 T-cell lymphoma invasion and metastasis 1 0.299452
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.298964
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.298516
USP10 ubiquitin specific peptidase 10 0.298516
KAT2B K(lysine) acetyltransferase 2B 0.296483
LINC00189 long intergenic non-protein coding RNA 189 0.29473
DCC DCC netrin 1 receptor 0.293189
CCDC23 coiled-coil domain containing 23 0.292078
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.292078
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.291058
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.290577
RLF rearranged L-myc fusion 0.290577
MORC3 MORC family CW-type zinc finger 3 0.289557
OGFRL1 opioid growth factor receptor-like 1 0.288921
FRMD8 FERM domain containing 8 0.288715
PCSK6 proprotein convertase subtilisin/kexin type 6 0.286288
IQSEC3 IQ motif and Sec7 domain 3 0.284571
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.284303
STIM2 stromal interaction molecule 2 0.283032
PLD5 phospholipase D family, member 5 0.28287
SLC39A10 solute carrier family 39 (zinc transporter), member 10 0.282242
MAN1B1 mannosidase, alpha, class 1B, member 1 0.282165
LOC146513 uncharacterized LOC146513 0.281787
SHROOM3 shroom family member 3 0.281787
ZMYND15 zinc finger, MYND-type containing 15 0.280918
TTYH1 tweety family member 1 0.279384
HIAT1 hippocampus abundant transcript 1 0.279321
LOC100507195 uncharacterized LOC100507195 0.279133
DRD1 dopamine receptor D1 0.278764
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 0.278111
SPHKAP SPHK1 interactor, AKAP domain containing 0.277375
BTNL2 butyrophilin-like 2 0.277156
JARID2 jumonji, AT rich interactive domain 2 0.276994
STK4 serine/threonine kinase 4 0.276834
ALKBH6 alkB, alkylation repair homolog 6 (E. coli) 0.276057
PEX14 peroxisomal biogenesis factor 14 0.275513
SASS6 spindle assembly 6 homolog (C. elegans) 0.275465
DOCK1 dedicator of cytokinesis 1 0.27532
RPRD2 regulation of nuclear pre-mRNA domain containing 2 0.274849
CLIP3 CAP-GLY domain containing linker protein 3 0.274483
NXPH1 neurexophilin 1 0.274438
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.274081
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.2725
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.2725
PNLIP pancreatic lipase 0.272382
SCARB1 scavenger receptor class B, member 1 0.272227
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.272111
PTPRO protein tyrosine phosphatase, receptor type, O 0.271111
GLCCI1 glucocorticoid induced 1 0.271111
PAQR5 progestin and adipoQ receptor family member V 0.27104
GPA33 glycoprotein A33 (transmembrane) 0.271004
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.270515
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 0.270143
SP100 SP100 nuclear antigen 0.269943
ATF6 activating transcription factor 6 0.269943
NRSN1 neurensin 1 0.269267
NKAIN3 Na+/K+ transporting ATPase interacting 3 0.269236
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 0.269111
GTSF1 gametocyte specific factor 1 0.268935
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.268692
IRF4 interferon regulatory factor 4 0.268589
FAM13A family with sequence similarity 13, member A 0.268317
DPH6 diphthamine biosynthesis 6 0.268116
TOX thymocyte selection-associated high mobility group box 0.268016
MRPL23 mitochondrial ribosomal protein L23 0.267115
FOXP1 forkhead box P1 0.267115
SH3YL1 SH3 and SYLF domain containing 1 0.267021
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.26638
OR2M7 olfactory receptor, family 2, subfamily M, member 7 0.26635
ABCC13 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene 0.266055
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense 0.265967
MAMDC2 MAM domain containing 2 0.26588
LOC285768 uncharacterized LOC285768 0.265592
LEPR leptin receptor 0.265479
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.265115
SDK1 sidekick cell adhesion molecule 1 0.265005
KCTD10 potassium channel tetramerization domain containing 10 0.264977
MED13L mediator complex subunit 13-like 0.264787
PPA2 pyrophosphatase (inorganic) 2 0.264652
PARD3B par-3 family cell polarity regulator beta 0.264385
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.26428
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.263917
ANKAR ankyrin and armadillo repeat containing 0.263362
SLC38A9 solute carrier family 38, member 9 0.263019
UBE3B ubiquitin protein ligase E3B 0.262802
ARHGAP26 Rho GTPase activating protein 26 0.262778
DLG2 discs, large homolog 2 (Drosophila) 0.262447
PARK2 parkin RBR E3 ubiquitin protein ligase 0.262238
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.262192
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.262077
PITPNM3 PITPNM family member 3 0.262008
DOCK5 dedicator of cytokinesis 5 0.261693
CDH23 cadherin-related 23 0.261405
TTLL6 tubulin tyrosine ligase-like family member 6 0.261231
TMEM222 transmembrane protein 222 0.260824
CEP128 centrosomal protein 128kDa 0.260489
SFTA3 surfactant associated 3 0.260469
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.259761
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.259682
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.259623
VWA3B von Willebrand factor A domain containing 3B 0.259623
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.259565
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.259467
AADACL3 arylacetamide deacetylase-like 3 0.259313
SRBD1 S1 RNA binding domain 1 0.259046
PLSCR3 phospholipid scramblase 3 0.258746
ARID1A AT rich interactive domain 1A (SWI-like) 0.258599
INSC inscuteable homolog (Drosophila) 0.25838
MSRA methionine sulfoxide reductase A 0.258236
EXT1 exostosin glycosyltransferase 1 0.258146
SPP2 secreted phosphoprotein 2, 24kDa 0.258128
LOXHD1 lipoxygenase homology domains 1 0.258075
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.258039
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.25781
SLIT3 slit homolog 3 (Drosophila) 0.257688
MVK mevalonate kinase 0.257688
MROH2A maestro heat-like repeat family member 2A 0.257619
RAI1 retinoic acid induced 1 0.25755
MTUS1 microtubule associated tumor suppressor 1 0.257278
ADGRB3 adhesion G protein-coupled receptor B3 0.257261
SASH1 SAM and SH3 domain containing 1 0.25691
ONECUT2 one cut homeobox 2 0.256779