negative regulation of response to external stimulus Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. (Gene Ontology, GO_0032102)
External Link http://amigo.geneontology.org/amigo/term/GO:0032102
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Genes

221 genes participating in the negative regulation of response to external stimulus biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABR active BCR-related
ACP5 acid phosphatase 5, tartrate resistant
ADA adenosine deaminase
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA1 adenosine A1 receptor
AIF1 allograft inflammatory factor 1
ALOX12 arachidonate 12-lipoxygenase
ANGPT2 angiopoietin 2
ANXA2 annexin A2
APCS amyloid P component, serum
APOA1 apolipoprotein A-I
APOD apolipoprotein D
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BBS2 Bardet-Biedl syndrome 2
BBS4 Bardet-Biedl syndrome 4
BCR breakpoint cluster region
C1QBP complement component 1, q subcomponent binding protein
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C5 complement component 5
C5AR2 complement component 5a receptor 2
CACTIN cactin, spliceosome C complex subunit
CALCRL calcitonin receptor-like
CARTPT CART prepropeptide
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCK cholecystokinin
CCL2 chemokine (C-C motif) ligand 2
CD109 CD109 molecule
CD276 CD276 molecule
CD34 CD34 molecule
CHID1 chitinase domain containing 1
CHMP4A charged multivesicular body protein 4A
CHMP4B charged multivesicular body protein 4B
CLN3 ceroid-lipofuscinosis, neuronal 3
CNR2 cannabinoid receptor 2 (macrophage)
CPB2 carboxypeptidase B2 (plasma)
CTNNA2 catenin (cadherin-associated protein), alpha 2
CXCL13 chemokine (C-X-C motif) ligand 13
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DEFB114 defensin, beta 114
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DUSP10 dual specificity phosphatase 10
DVL1 dishevelled segment polarity protein 1
EDN1 endothelin 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELANE elastase, neutrophil expressed
EPHA4 EPH receptor A4
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
FABP7 fatty acid binding protein 7, brain
FAM132A family with sequence similarity 132, member A
FEM1A fem-1 homolog a (C. elegans)
FFAR4 free fatty acid receptor 4
FGF2 fibroblast growth factor 2 (basic)
FOXF1 forkhead box F1
FOXP3 forkhead box P3
GATA3 GATA binding protein 3
GBA glucosidase, beta, acid
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GJA1 gap junction protein, alpha 1, 43kDa
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP5 glycoprotein V (platelet)
GPER1 G protein-coupled estrogen receptor 1
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GREM1 gremlin 1, DAN family BMP antagonist
GRID2 glutamate receptor, ionotropic, delta 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GSTP1 glutathione S-transferase pi 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HRG histidine-rich glycoprotein
HTRA1 HtrA serine peptidase 1
IER3 immediate early response 3
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL10 interleukin 10
IL12B interleukin 12B
IL2 interleukin 2
IL20RB interleukin 20 receptor beta
IL22RA2 interleukin 22 receptor, alpha 2
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
INS insulin
IRF3 interferon regulatory factor 3
IRG1 immunoresponsive 1 homolog (mouse)
ISL1 ISL LIM homeobox 1
ITCH itchy E3 ubiquitin protein ligase
KANK2 KN motif and ankyrin repeat domains 2
KLF4 Kruppel-like factor 4 (gut)
KLK8 kallikrein-related peptidase 8
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KNG1 kininogen 1
KRT1 keratin 1, type II
LEP leptin
LTF lactotransferrin
LZTS1 leucine zipper, putative tumor suppressor 1
MAPK7 mitogen-activated protein kinase 7
MEFV Mediterranean fever
METRNL meteorin, glial cell differentiation regulator-like
MICB MHC class I polypeptide-related sequence B
MKKS McKusick-Kaufman syndrome
MMP26 matrix metallopeptidase 26
MMP28 matrix metallopeptidase 28
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVK mevalonate kinase
NDFIP1 Nedd4 family interacting protein 1
NENF neudesin neurotrophic factor
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NLRX1 NLR family member X1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPC1 Niemann-Pick disease, type C1
NPFF neuropeptide FF-amide peptide precursor
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRBP2 nuclear receptor binding protein 2
NRP1 neuropilin 1
NRXN1 neurexin 1
NT5E 5'-nucleotidase, ecto (CD73)
OTULIN OTU deubiquitinase with linear linkage specificity
PADI2 peptidyl arginine deiminase, type II
PBK PDZ binding kinase
PCBP2 poly(rC) binding protein 2
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PGLYRP1 peptidoglycan recognition protein 1
PINK1 PTEN induced putative kinase 1
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLG plasminogen
PLXNA3 plexin A3
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PRDM1 PR domain containing 1, with ZNF domain
PRKCD protein kinase C, delta
PRKG1 protein kinase, cGMP-dependent, type I
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRO protein tyrosine phosphatase, receptor type, O
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
RORA RAR-related orphan receptor A
RPS19 ribosomal protein S19
SAA1 serum amyloid A1
SCFD1 sec1 family domain containing 1
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SHARPIN SHANK-associated RH domain interactor
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIRT2 sirtuin 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLIT1 slit homolog 1 (Drosophila)
SLIT2 slit homolog 2 (Drosophila)
SMAD3 SMAD family member 3
SNAI2 snail family zinc finger 2
SOCS3 suppressor of cytokine signaling 3
SPP1 secreted phosphoprotein 1
SPX spexin hormone
TARBP2 TAR (HIV-1) RNA binding protein 2
TEK TEK tyrosine kinase, endothelial
TFF2 trefoil factor 2
THBD thrombomodulin
THBS1 thrombospondin 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TMPRSS6 transmembrane protease, serine 6
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNR tenascin R
TP53 tumor protein p53
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIB1 tribbles pseudokinase 1
TRIM38 tripartite motif containing 38
TSPAN6 tetraspanin 6
TSPAN8 tetraspanin 8
TYRO3 TYRO3 protein tyrosine kinase
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBASH3B ubiquitin associated and SH3 domain containing B
UCN urocortin
VIMP VCP-interacting membrane selenoprotein
VTN vitronectin
WNT3 wingless-type MMTV integration site family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
ZFP36 ZFP36 ring finger protein