negative regulation of leukocyte activation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. (Gene Ontology, GO_0002695)
External Link http://amigo.geneontology.org/amigo/term/GO:0002695
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Genes

120 genes participating in the negative regulation of leukocyte activation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABR active BCR-related
ATM ATM serine/threonine kinase
AXL AXL receptor tyrosine kinase
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BMP4 bone morphogenetic protein 4
BPI bactericidal/permeability-increasing protein
BTLA B and T lymphocyte associated
BTN2A2 butyrophilin, subfamily 2, member A2
C10ORF54 chromosome 10 open reading frame 54
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCR2 chemokine (C-C motif) receptor 2
CD274 CD274 molecule
CD276 CD276 molecule
CD300A CD300a molecule
CD37 CD37 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYLD cylindromatosis (turban tumor syndrome)
DLG1 discs, large homolog 1 (Drosophila)
DTX1 deltex 1, E3 ubiquitin ligase
DUSP3 dual specificity phosphatase 3
ERBB2 erb-b2 receptor tyrosine kinase 2
FAS Fas cell surface death receptor
FBXO7 F-box protein 7
FER fer (fps/fes related) tyrosine kinase
FLT3 fms-related tyrosine kinase 3
FOXF1 forkhead box F1
FOXJ1 forkhead box J1
FOXP3 forkhead box P3
GAL galanin/GMAP prepropeptide
GLI3 GLI family zinc finger 3
GLMN glomulin, FKBP associated protein
GPER1 G protein-coupled estrogen receptor 1
HLA-G major histocompatibility complex, class I, G
HLX H2.0-like homeobox
HMGB3 high mobility group box 3
HMOX1 heme oxygenase 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IFNA2 interferon, alpha 2
IFNB1 interferon, beta 1, fibroblast
IFNL1 interferon, lambda 1
IHH indian hedgehog
IL10 interleukin 10
IL2 interleukin 2
IL20RB interleukin 20 receptor beta
IL2RA interleukin 2 receptor, alpha
IL31RA interleukin 31 receptor A
IL4 interleukin 4
IL4R interleukin 4 receptor
INHA inhibin, alpha
INHBA inhibin, beta A
IRF1 interferon regulatory factor 1
ITCH itchy E3 ubiquitin protein ligase
JAK3 Janus kinase 3
LAG3 lymphocyte-activation gene 3
LAX1 lymphocyte transmembrane adaptor 1
LGALS3 lectin, galactoside-binding, soluble, 3
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LRRC32 leucine rich repeat containing 32
LST1 leukocyte specific transcript 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MERTK MER proto-oncogene, tyrosine kinase
MICA MHC class I polypeptide-related sequence A
MILR1 mast cell immunoglobulin-like receptor 1
MNDA myeloid cell nuclear differentiation antigen
NDFIP1 Nedd4 family interacting protein 1
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRARP NOTCH-regulated ankyrin repeat protein
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAWR PRKC, apoptosis, WT1, regulator
PDCD1LG2 programmed cell death 1 ligand 2
PDE5A phosphodiesterase 5A, cGMP-specific
PELI1 pellino E3 ubiquitin protein ligase 1
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PRDM1 PR domain containing 1, with ZNF domain
PRNP prion protein
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RC3H1 ring finger and CCCH-type domains 1
RHBDD3 rhomboid domain containing 3
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SFRP1 secreted frizzled-related protein 1
SFTPD surfactant protein D
SHH sonic hedgehog
SLA2 Src-like-adaptor 2
SOCS5 suppressor of cytokine signaling 5
SOCS6 suppressor of cytokine signaling 6
SOX11 SRY (sex determining region Y)-box 11
TBC1D10C TBC1 domain family, member 10C
TFF2 trefoil factor 2
TGFB1 transforming growth factor, beta 1
THOC1 THO complex 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TSPAN32 tetraspanin 32
TYRO3 TYRO3 protein tyrosine kinase
VSIG4 V-set and immunoglobulin domain containing 4
VTCN1 V-set domain containing T cell activation inhibitor 1
XCL1 chemokine (C motif) ligand 1
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H8 zinc finger CCCH-type containing 8