nausea and vomiting Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0002017
Similar Terms
Downloads & Tools

Genes

249 genes associated with the nausea and vomiting phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
HBB hemoglobin, beta 2.11867
OR51F1 olfactory receptor, family 51, subfamily F, member 1 (gene/pseudogene) 1.46713
OR51B5 olfactory receptor, family 51, subfamily B, member 5 1.33952
IL2RB interleukin 2 receptor, beta 1.27093
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 1.22719
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 1.18324
DLC1 DLC1 Rho GTPase activating protein 1.15702
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 1.14966
OSTM1 osteopetrosis associated transmembrane protein 1 1.14354
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 1.13983
KRT1 keratin 1, type II 1.12677
NDP Norrie disease (pseudoglioma) 1.12438
ARL15 ADP-ribosylation factor-like 15 1.11779
RGS7 regulator of G-protein signaling 7 1.11073
DENND1B DENN/MADD domain containing 1B 1.10661
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 1.10622
FRMPD4 FERM and PDZ domain containing 4 1.10597
BCAS1 breast carcinoma amplified sequence 1 1.10446
CSMD3 CUB and Sushi multiple domains 3 1.09783
LRP1B low density lipoprotein receptor-related protein 1B 1.09409
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 1.08951
ARHGAP31 Rho GTPase activating protein 31 1.08856
STAMBPL1 STAM binding protein-like 1 1.08193
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 1.07805
CSMD1 CUB and Sushi multiple domains 1 1.07701
CSMD2 CUB and Sushi multiple domains 2 1.07315
STARD13 StAR-related lipid transfer (START) domain containing 13 1.07284
ADGRD1 adhesion G protein-coupled receptor D1 1.06834
KIAA1217 KIAA1217 1.06576
SIRT4 sirtuin 4 1.06211
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 1.05929
OCA2 oculocutaneous albinism II 1.05886
NOS1 nitric oxide synthase 1 (neuronal) 1.05826
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 1.04543
ARG1 arginase 1 1.03935
C6ORF183 chromosome 6 open reading frame 183 1.02289
DBNL drebrin-like 1.02082
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 1.00989
DRAM1 DNA-damage regulated autophagy modulator 1 0.979804
PCDH15 protocadherin-related 15 0.976371
C10ORF32 chromosome 10 open reading frame 32 0.975163
EBF3 early B-cell factor 3 0.973975
APOLD1 apolipoprotein L domain containing 1 0.972518
FGF10 fibroblast growth factor 10 0.960098
PPAT phosphoribosyl pyrophosphate amidotransferase 0.954239
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.952379
OFCC1 orofacial cleft 1 candidate 1 0.952379
SLC10A7 solute carrier family 10, member 7 0.949544
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.944405
GRIK1 glutamate receptor, ionotropic, kainate 1 0.944168
SCUBE1 signal peptide, CUB domain, EGF-like 1 0.942073
FA2H fatty acid 2-hydroxylase 0.934387
RPRD2 regulation of nuclear pre-mRNA domain containing 2 0.918332
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.916747
NPSR1 neuropeptide S receptor 1 0.905315
UNC5D unc-5 homolog D (C. elegans) 0.90455
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 0.90398
PTPRR protein tyrosine phosphatase, receptor type, R 0.903038
CCDC162P coiled-coil domain containing 162, pseudogene 0.903038
EXT1 exostosin glycosyltransferase 1 0.903038
MYLK myosin light chain kinase 0.898479
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.897244
ADAM28 ADAM metallopeptidase domain 28 0.895509
NAV2 neuron navigator 2 0.879986
CDH13 cadherin 13 0.877841
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.877841
ICK intestinal cell (MAK-like) kinase 0.877388
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.876638
ANK2 ankyrin 2, neuronal 0.875894
ADGRF5 adhesion G protein-coupled receptor F5 0.874864
GSDMA gasdermin A 0.870579
PDGFD platelet derived growth factor D 0.868513
C8ORF34 chromosome 8 open reading frame 34 0.865569
ZNF366 zinc finger protein 366 0.865044
SDK1 sidekick cell adhesion molecule 1 0.862558
GRM7 glutamate receptor, metabotropic 7 0.862558
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.858744
HPSE heparanase 0.854734
COL25A1 collagen, type XXV, alpha 1 0.850336
ANKRD22 ankyrin repeat domain 22 0.846476
HK2 hexokinase 2 0.840142
DPYSL2 dihydropyrimidinase-like 2 0.837193
NLRC5 NLR family, CARD domain containing 5 0.832497
MAP3K7CL MAP3K7 C-terminal like 0.828053
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 0.827192
OSBPL1A oxysterol binding protein-like 1A 0.820614
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.81905
PCSK2 proprotein convertase subtilisin/kexin type 2 0.81297
FLJ26850 FLJ26850 protein 0.809986
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.807106
AEBP1 AE binding protein 1 0.807106
LOC285423 uncharacterized LOC285423 0.798387
TECRL trans-2,3-enoyl-CoA reductase-like 0.7965
GK glycerol kinase 0.788506
BMP5 bone morphogenetic protein 5 0.787873
GPR88 G protein-coupled receptor 88 0.784165
PRDM14 PR domain containing 14 0.783563
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.782369
SAMD9 sterile alpha motif domain containing 9 0.777754
VRK3 vaccinia related kinase 3 0.772842
ADGRF1 adhesion G protein-coupled receptor F1 0.768197
DIEXF digestive organ expansion factor homolog (zebrafish) 0.764625
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.764079
FBXO21 F-box protein 21 0.761926
PTPRT protein tyrosine phosphatase, receptor type, T 0.757765
KIRREL kin of IRRE like (Drosophila) 0.755257
LOXHD1 lipoxygenase homology domains 1 0.752816
STK31 serine/threonine kinase 31 0.751857
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.74997
PRMT1 protein arginine methyltransferase 1 0.74997
ZNF81 zinc finger protein 81 0.749505
WWOX WW domain containing oxidoreductase 0.748581
GUSBP11 glucuronidase, beta pseudogene 11 0.739411
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.73677
SERGEF secretion regulating guanine nucleotide exchange factor 0.734978
DMD dystrophin 0.733218
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative) 0.732783
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.732783
WDR33 WD repeat domain 33 0.729372
LSAMP limbic system-associated membrane protein 0.728123
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.726891
PLA2G3 phospholipase A2, group III 0.726484
CDH23 cadherin-related 23 0.725273
SCTR secretin receptor 0.722896
SGCZ sarcoglycan, zeta 0.722116
ASTN2 astrotactin 2 0.72096
SORCS3 sortilin-related VPS10 domain containing receptor 3 0.720577
EPHA5 EPH receptor A5 0.717572
ARID1B AT rich interactive domain 1B (SWI1-like) 0.713592
CNTNAP4 contactin associated protein-like 4 0.712186
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.712186
CRX cone-rod homeobox 0.711491
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.708638
PRKCE protein kinase C, epsilon 0.706786
ZNF468 zinc finger protein 468 0.704251
GRID2 glutamate receptor, ionotropic, delta 2 0.702831
TTC7B tetratricopeptide repeat domain 7B 0.701779
WDR25 WD repeat domain 25 0.701084
CPT1A carnitine palmitoyltransferase 1A (liver) 0.699708
PAAF1 proteasomal ATPase-associated factor 1 0.69439
CPM carboxypeptidase M 0.690896
DNAH11 dynein, axonemal, heavy chain 11 0.690896
PVT1 Pvt1 oncogene (non-protein coding) 0.688736
SMC6 structural maintenance of chromosomes 6 0.688736
KCNIP4 Kv channel interacting protein 4 0.686028
FAM155A family with sequence similarity 155, member A 0.67722
SLCO5A1 solute carrier organic anion transporter family, member 5A1 0.675124
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.674532
SCCPDH saccharopine dehydrogenase (putative) 0.663117
MATN2 matrilin 2 0.660262
GRM8 glutamate receptor, metabotropic 8 0.657985
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.657985
NTN1 netrin 1 0.656496
BMPR1A bone morphogenetic protein receptor, type IA 0.648376
CPLX2 complexin 2 0.646866
IL33 interleukin 33 0.646866
TRPS1 trichorhinophalangeal syndrome I 0.644886
COL27A1 collagen, type XXVII, alpha 1 0.644641
SAMD9L sterile alpha motif domain containing 9-like 0.643425
HEPHL1 hephaestin-like 1 0.642462
TCF4 transcription factor 4 0.640562
TSPAN18 tetraspanin 18 0.639159
UBE3C ubiquitin protein ligase E3C 0.637546
MIR99AHG mir-99a-let-7c cluster host gene 0.636862
AATK-AS1 AATK antisense RNA 1 0.636862
XYLT1 xylosyltransferase I 0.632198
CEP57L1 centrosomal protein 57kDa-like 1 0.630903
AADAC arylacetamide deacetylase 0.630689
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.628153
RFX2 regulatory factor X, 2 (influences HLA class II expression) 0.625067
HHLA2 HERV-H LTR-associating 2 0.623859
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.623859
HIF3A hypoxia inducible factor 3, alpha subunit 0.623659
ZNF395 zinc finger protein 395 0.620318
ZNF844 zinc finger protein 844 0.618973
SMOC1 SPARC related modular calcium binding 1 0.617459
PTPRD protein tyrosine phosphatase, receptor type, D 0.614969
FER fer (fps/fes related) tyrosine kinase 0.613457
NKX2-6 NK2 homeobox 6 0.612523
PROX1-AS1 PROX1 antisense RNA 1 0.611966
CCDC3 coiled-coil domain containing 3 0.611597
WRB tryptophan rich basic protein 0.60977
DLG2 discs, large homolog 2 (Drosophila) 0.609408
MYOM2 myomesin 2 0.609228
AKAP6 A kinase (PRKA) anchor protein 6 0.60851
NTM neurotrimin 0.608332
ZNF488 zinc finger protein 488 0.607975
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.60709
CHRM5 cholinergic receptor, muscarinic 5 0.60465
OR2L13 olfactory receptor, family 2, subfamily L, member 13 0.602774
GLI2 GLI family zinc finger 2 0.6021
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.6021
CNTNAP2 contactin associated protein-like 2 0.601264
CHN2 chimerin 2 0.60027
COTL1 coactosin-like F-actin binding protein 1 0.598797
ATP9A ATPase, class II, type 9A 0.596389
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 0.593914
TLL1 tolloid-like 1 0.593729
KCTD16 potassium channel tetramerization domain containing 16 0.589645
KIF13B kinesin family member 13B 0.585383
SUGCT succinyl-CoA:glutarate-CoA transferase 0.585136
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.584889
EIF3K eukaryotic translation initiation factor 3, subunit K 0.583787
SPHKAP SPHK1 interactor, AKAP domain containing 0.583787
DOCK1 dedicator of cytokinesis 1 0.581504
PMEPA1 prostate transmembrane protein, androgen induced 1 0.580327
C1ORF159 chromosome 1 open reading frame 159 0.579512
BTBD9 BTB (POZ) domain containing 9 0.579512
CDK8 cyclin-dependent kinase 8 0.57928
STAT5B signal transducer and activator of transcription 5B 0.578819
LOC100287944 uncharacterized LOC100287944 0.577563
RIC8B RIC8 guanine nucleotide exchange factor B 0.576549
GRXCR1 glutaredoxin, cysteine rich 1 0.574338
ZNF804A zinc finger protein 804A 0.572823
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.492995
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.488013
OR51E2 olfactory receptor, family 51, subfamily E, member 2 0.486267
MAST2 microtubule associated serine/threonine kinase 2 0.474275
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.471675
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 0.471675
PLXNA4 plexin A4 0.467318
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.467318
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 0.45977
PARK2 parkin RBR E3 ubiquitin protein ligase 0.456462
PLEKHA6 pleckstrin homology domain containing, family A member 6 0.456462
FAM53B family with sequence similarity 53, member B 0.450426
CIAPIN1 cytokine induced apoptosis inhibitor 1 0.431891
STON2 stonin 2 0.427648
MAML2 mastermind-like 2 (Drosophila) 0.427648
MTMR10 myotubularin related protein 10 0.420874
MEIS1 Meis homeobox 1 0.420874
HNMT histamine N-methyltransferase 0.419527
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 0.41764
TSHZ2 teashirt zinc finger homeobox 2 0.416832
STAC SH3 and cysteine rich domain 0.416832
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.414683
OR13D1 olfactory receptor, family 13, subfamily D, member 1 0.412337
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.411207
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.411057
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.410342
LOC648987 uncharacterized LOC648987 0.410071
ZNF329 zinc finger protein 329 0.409549
RYR2 ryanodine receptor 2 (cardiac) 0.409549
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.409175
OPCML opioid binding protein/cell adhesion molecule-like 0.408934
LOC400927 TPTE and PTEN homologous inositol lipid phosphatase pseudogene 0.408816
LINC01587 long intergenic non-protein coding RNA 1587 0.4087
DCLK1 doublecortin-like kinase 1 0.407829
DEPTOR DEP domain containing MTOR-interacting protein 0.406207