nascent polypeptide-associated complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome. (Gene Ontology, GO_0005854)
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Genes

277 proteins co-occuring with the nascent polypeptide-associated complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NACA nascent polypeptide-associated complex alpha subunit 1.77665
CAT catalase 1.74511
SOD2 superoxide dismutase 2, mitochondrial 1.68909
NACA3P NACA family member 3 pseudogene 1.64733
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.58334
GPX1 glutathione peroxidase 1 1.48758
GPX4 glutathione peroxidase 4 1.48136
GPX5 glutathione peroxidase 5 1.4791
ARG2 arginase 2 1.37023
ERBB2 erb-b2 receptor tyrosine kinase 2 1.26604
BAX BCL2-associated X protein 1.26286
TNF tumor necrosis factor 1.22412
JUN jun proto-oncogene 1.17876
BTF3 basic transcription factor 3 1.16184
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.14239
MPO myeloperoxidase 1.11786
HMOX1 heme oxygenase 1 1.1148
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.0741
SYCN syncollin 1.06954
ANXA5 annexin A5 1.06751
GSR glutathione reductase 1.0243
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.01387
TP53 tumor protein p53 1.0104
CRYGD crystallin, gamma D 0.995142
MAPK8 mitogen-activated protein kinase 8 0.980987
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.975166
IL1B interleukin 1, beta 0.963588
MYB v-myb avian myeloblastosis viral oncogene homolog 0.958789
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.954005
GSTA4 glutathione S-transferase alpha 4 0.936432
GSTA1 glutathione S-transferase alpha 1 0.933129
GHRH growth hormone releasing hormone 0.928892
GSTA3 glutathione S-transferase alpha 3 0.927483
GSTA2 glutathione S-transferase alpha 2 0.925604
TXLNG taxilin gamma 0.877791
PARP1 poly (ADP-ribose) polymerase 1 0.87733
HOMER2 homer scaffolding protein 2 0.865826
ALB albumin 0.821288
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.817158
CST3 cystatin C 0.811193
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.764982
EGFR epidermal growth factor receptor 0.764072
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.755891
TXN thioredoxin 0.749546
ICAM1 intercellular adhesion molecule 1 0.739163
FOS FBJ murine osteosarcoma viral oncogene homolog 0.736913
ELANE elastase, neutrophil expressed 0.734217
FBXL20 F-box and leucine-rich repeat protein 20 0.734217
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.722134
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.70439
NOS3 nitric oxide synthase 3 (endothelial cell) 0.688139
CCL2 chemokine (C-C motif) ligand 2 0.679413
GSS glutathione synthetase 0.666394
MMP9 matrix metallopeptidase 9 0.665529
HAL histidine ammonia-lyase 0.659482
TXLNA taxilin alpha 0.65388
PGR progesterone receptor 0.642286
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.640573
ALAD aminolevulinate dehydratase 0.629892
MMP2 matrix metallopeptidase 2 0.629039
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.625206
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 0.622229
BCL7B B-cell CLL/lymphoma 7B 0.622229
POMC proopiomelanocortin 0.615861
F2 coagulation factor II (thrombin) 0.615013
IL6 interleukin 6 0.614589
IGKV1-17 immunoglobulin kappa variable 1-17 0.609086
DNAH8 dynein, axonemal, heavy chain 8 0.60655
ASIC3 acid sensing (proton gated) ion channel 3 0.59896
DDIT3 DNA-damage-inducible transcript 3 0.596855
ACE angiotensin I converting enzyme 0.592652
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.575078
ESR1 estrogen receptor 1 0.572994
VIP vasoactive intestinal peptide 0.568832
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 0.568416
INS insulin 0.5597
SCN2A sodium channel, voltage gated, type II alpha subunit 0.557214
MAP3K11 mitogen-activated protein kinase kinase kinase 11 0.555973
CCND1 cyclin D1 0.555559
DNTT DNA nucleotidylexotransferase 0.551425
BCL2L1 BCL2-like 1 0.549773
OR5K1 olfactory receptor, family 5, subfamily K, member 1 0.540294
MGAM maltase-glucoamylase 0.535361
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.532898
OR1J1 olfactory receptor, family 1, subfamily J, member 1 0.532078
HSPA4 heat shock 70kDa protein 4 0.524704
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.520615
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.519798
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.519798
CXCL8 chemokine (C-X-C motif) ligand 8 0.515716
BECN1 beclin 1, autophagy related 0.514493
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 0.509604
FASLG Fas ligand (TNF superfamily, member 6) 0.505537
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 0.503912
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.501881
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.498636
MAPK14 mitogen-activated protein kinase 14 0.497826
CLEC4F C-type lectin domain family 4, member F 0.49499
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 0.49418
PILRB paired immunoglobin-like type 2 receptor beta 0.489731
ALPPL2 alkaline phosphatase, placental-like 2 0.482467
GCLC glutamate-cysteine ligase, catalytic subunit 0.482064
ALPP alkaline phosphatase, placental 0.481661
ALPL alkaline phosphatase, liver/bone/kidney 0.481661
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.477233
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 0.475625
NTSR1 neurotensin receptor 1 (high affinity) 0.4608
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.460401
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.457208
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.457208
GUCY2C guanylate cyclase 2C 0.456012
NPR1 natriuretic peptide receptor 1 0.447259
NOS2 nitric oxide synthase 2, inducible 0.442104
GSTP1 glutathione S-transferase pi 1 0.439728
GRID2 glutamate receptor, ionotropic, delta 2 0.433012
PRKCSH protein kinase C substrate 80K-H 0.429465
NOX4 NADPH oxidase 4 0.425138
ENDOG endonuclease G 0.41886
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.415337
SCN3A sodium channel, voltage gated, type III alpha subunit 0.408699
TGFB1 transforming growth factor, beta 1 0.408309
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.40675
PRDX1 peroxiredoxin 1 0.404415
BCL2 B-cell CLL/lymphoma 2 0.403637
GLO1 glyoxalase I 0.403248
FADD Fas (TNFRSF6)-associated via death domain 0.402081
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 0.401304
ATF4 activating transcription factor 4 0.399363
TSPO translocator protein (18kDa) 0.396648
COMT catechol-O-methyltransferase 0.393549
GRM2 glutamate receptor, metabotropic 2 0.393162
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.385822
SORD sorbitol dehydrogenase 0.383509
CRP C-reactive protein, pentraxin-related 0.382739
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.382354
VEGFA vascular endothelial growth factor A 0.378507
PRDX2 peroxiredoxin 2 0.374283
NACAD NAC alpha domain containing 0.370067
GGT1 gamma-glutamyltransferase 1 0.367771
EPHB2 EPH receptor B2 0.365477
BIRC5 baculoviral IAP repeat containing 5 0.356324
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.355563
RPL7P32 ribosomal protein L7 pseudogene 32 0.354042
PRDX5 peroxiredoxin 5 0.353662
TH tyrosine hydroxylase 0.350243
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.348725
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 0.348346
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.347208
CNPY2 canopy FGF signaling regulator 2 0.340773
DAND5 DAN domain family member 5, BMP antagonist 0.337373
CD4 CD4 molecule 0.336996
EDN1 endothelin 1 0.336619
OPLAH 5-oxoprolinase (ATP-hydrolysing) 0.332472
GADD45G growth arrest and DNA-damage-inducible, gamma 0.331342
MAPK3 mitogen-activated protein kinase 3 0.330966
H2AFX H2A histone family, member X 0.330213
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.326078
LMTK3 lemur tyrosine kinase 3 0.325702
IL1A interleukin 1, alpha 0.321201
CA2 carbonic anhydrase II 0.31783
SAP30BP SAP30 binding protein 0.316708
ABI3 ABI family, member 3 0.314091
G6PD glucose-6-phosphate dehydrogenase 0.312971
USP24 ubiquitin specific peptidase 24 0.312224
CARD8 caspase recruitment domain family, member 8 0.310732
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 0.303283
GRM5 glutamate receptor, metabotropic 5 0.302912
TXNIP thioredoxin interacting protein 0.301797
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.300682
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) 0.29994
DUSP4 dual specificity phosphatase 4 0.299197
GGT2 gamma-glutamyltransferase 2 0.297713
HPN hepsin 0.291417
ANKRD11 ankyrin repeat domain 11 0.286245
NIPSNAP3B nipsnap homolog 3B (C. elegans) 0.284032
ERCC1 excision repair cross-complementation group 1 0.281085
ULK3 unc-51 like kinase 3 0.278877
IL10 interleukin 10 0.274101
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.273734
GPR83 G protein-coupled receptor 83 0.273
SMOX spermine oxidase 0.271167
MX2 MX dynamin-like GTPase 2 0.268237
DAD1 defender against cell death 1 0.265311
BCL7A B-cell CLL/lymphoma 7A 0.26385
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.26312
C20ORF85 chromosome 20 open reading frame 85 0.261296
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.260931
OXCT2 3-oxoacid CoA transferase 2 0.260931
ECD ecdysoneless homolog (Drosophila) 0.257289
ADIPOR2 adiponectin receptor 2 0.256925
REN renin 0.254743
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.252927
MAPK10 mitogen-activated protein kinase 10 0.251476
CARD17 caspase recruitment domain family, member 17 0.251114
IL4 interleukin 4 0.248216
FXYD1 FXYD domain containing ion transport regulator 1 0.247492
ASIC5 acid sensing (proton gated) ion channel family member 5 0.24713
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.244601
ADCK3 aarF domain containing kinase 3 0.244601
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.243879
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 0.243158
CCK cholecystokinin 0.240996
EDF1 endothelial differentiation-related factor 1 0.240276
TAC1 tachykinin, precursor 1 0.238837
FRS2 fibroblast growth factor receptor substrate 2 0.238837
VCAM1 vascular cell adhesion molecule 1 0.234174
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.231672
OPRM1 opioid receptor, mu 1 0.231315
UMPS uridine monophosphate synthetase 0.227752
ASPRV1 aspartic peptidase, retroviral-like 1 0.225976
NKX6-2 NK6 homeobox 2 0.22385
PCBP4 poly(rC) binding protein 4 0.223497
RAD54B RAD54 homolog B (S. cerevisiae) 0.222436
ATM ATM serine/threonine kinase 0.222083
CDC25C cell division cycle 25C 0.22173
CCNE1 cyclin E1 0.219969
PDGFB platelet-derived growth factor beta polypeptide 0.219265
CREB1 cAMP responsive element binding protein 1 0.218212
CYBA cytochrome b-245, alpha polypeptide 0.215412
GRM1 glutamate receptor, metabotropic 1 0.215063
APAF1 apoptotic peptidase activating factor 1 0.211933
GHRHR growth hormone releasing hormone receptor 0.211933
PCNA proliferating cell nuclear antigen 0.208481
PAOX polyamine oxidase (exo-N4-amino) 0.207108
GLRX glutaredoxin (thioltransferase) 0.206766
C3ORF18 chromosome 3 open reading frame 18 0.206082
SLITRK1 SLIT and NTRK-like family, member 1 0.204718
TLR4 toll-like receptor 4 0.204378
FOXN3 forkhead box N3 0.204378
CARD6 caspase recruitment domain family, member 6 0.203699
ZBTB4 zinc finger and BTB domain containing 4 0.203699
FOXP3 forkhead box P3 0.200999
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.200328
DRD2 dopamine receptor D2 0.195681
TMEM131 transmembrane protein 131 0.193719
IL2 interleukin 2 0.193394
SELE selectin E 0.191135
OASL 2'-5'-oligoadenylate synthetase-like 0.191135
FN1 fibronectin 1 0.189539
CDK1 cyclin-dependent kinase 1 0.186397
HYAL1 hyaluronoglucosaminidase 1 0.185777
NFE2L2 nuclear factor, erythroid 2-like 2 0.184241
PPARG peroxisome proliferator-activated receptor gamma 0.183631
IDO1 indoleamine 2,3-dioxygenase 1 0.181823
IFNE interferon, epsilon 0.181227
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.180045
UTS2 urotensin 2 0.178588
QTRT1 queuine tRNA-ribosyltransferase 1 0.178011
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 0.177439
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.177439
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.176305
IL18 interleukin 18 0.174911
COX7C cytochrome c oxidase subunit VIIc 0.174635
NCF4 neutrophil cytosolic factor 4, 40kDa 0.173814
NOX1 NADPH oxidase 1 0.171149
APP amyloid beta (A4) precursor protein 0.170888
GPX6 glutathione peroxidase 6 0.170114
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.169859
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.167856
CD34 CD34 molecule 0.167366
HMGB1 high mobility group box 1 0.166884
MMP3 matrix metallopeptidase 3 0.166643
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.165932
NUPR1 nuclear protein, transcriptional regulator, 1 0.165463
CFLAR CASP8 and FADD-like apoptosis regulator 0.165463
POU3F3 POU class 3 homeobox 3 0.164542
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.163865
TPD52L1 tumor protein D52-like 1 0.1632
HPGDS hematopoietic prostaglandin D synthase 0.161693
CDK4 cyclin-dependent kinase 4 0.161693
NPS neuropeptide S 0.160658
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.159074
RGL2 ral guanine nucleotide dissociation stimulator-like 2 0.158882
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 0.158315
NRG1 neuregulin 1 0.157943
TCF3 transcription factor 3 0.157943
MAPK9 mitogen-activated protein kinase 9 0.157397