naringenin-4597 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the naringenin-4597 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY9 adenylate cyclase 9
AHSP alpha hemoglobin stabilizing protein
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARTN artemin
ASCL1 achaete-scute family bHLH transcription factor 1
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
B9D1 B9 protein domain 1
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CADM1 cell adhesion molecule 1
CAMKMT calmodulin-lysine N-methyltransferase
CARD9 caspase recruitment domain family, member 9
CHMP6 charged multivesicular body protein 6
CIDEC cell death-inducing DFFA-like effector c
CREM cAMP responsive element modulator
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CXCR4 chemokine (C-X-C motif) receptor 4
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EPX eosinophil peroxidase
ESRRG estrogen-related receptor gamma
ETV1 ets variant 1
FAM188A family with sequence similarity 188, member A
FGF4 fibroblast growth factor 4
GPR27 G protein-coupled receptor 27
GSTTP1 glutathione S-transferase theta pseudogene 1
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HOXB6 homeobox B6
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGFALS insulin-like growth factor binding protein, acid labile subunit
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL24 interleukin 24
ING2 inhibitor of growth family, member 2
ITGA7 integrin, alpha 7
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KIAA1456 KIAA1456
KIFC3 kinesin family member C3
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRIT1 KRIT1, ankyrin repeat containing
LDLRAD4 low density lipoprotein receptor class A domain containing 4
MAK male germ cell-associated kinase
MAU2 MAU2 sister chromatid cohesion factor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MET MET proto-oncogene, receptor tyrosine kinase
MPZL2 myelin protein zero-like 2
MTCP1 mature T-cell proliferation 1
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEBL nebulette
NNAT neuronatin
NNMT nicotinamide N-methyltransferase
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OTC ornithine carbamoyltransferase
PADI1 peptidyl arginine deiminase, type I
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE4D phosphodiesterase 4D, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA1A phospholipase A1 member A
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POFUT1 protein O-fucosyltransferase 1
PQLC2 PQ loop repeat containing 2
PRKCE protein kinase C, epsilon
PYY peptide YY
RABGAP1L RAB GTPase activating protein 1-like
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RGS10 regulator of G-protein signaling 10
RIMS2 regulating synaptic membrane exocytosis 2
RLN1 relaxin 1
RNF6 ring finger protein (C3H2C3 type) 6
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
SARM1 sterile alpha and TIR motif containing 1
SEC14L4 SEC14-like 4 (S. cerevisiae)
SETD1A SET domain containing 1A
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC22A14 solute carrier family 22, member 14
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SOGA1 suppressor of glucose, autophagy associated 1
SOX15 SRY (sex determining region Y)-box 15
SRP72 signal recognition particle 72kDa
SRSF1 serine/arginine-rich splicing factor 1
SRSF5 serine/arginine-rich splicing factor 5
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TLR4 toll-like receptor 4
TPPP tubulin polymerization promoting protein
TSC22D3 TSC22 domain family, member 3
UBA7 ubiquitin-like modifier activating enzyme 7
UCN urocortin
UTRN utrophin
VAV2 vav 2 guanine nucleotide exchange factor
ZNF268 zinc finger protein 268
ZNF44 zinc finger protein 44
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARL14 ADP-ribosylation factor-like 14
ARL15 ADP-ribosylation factor-like 15
ASB7 ankyrin repeat and SOCS box containing 7
ATAT1 alpha tubulin acetyltransferase 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BTF3P12 basic transcription factor 3 pseudogene 12
C6ORF47 chromosome 6 open reading frame 47
C7ORF43 chromosome 7 open reading frame 43
CA5B carbonic anhydrase VB, mitochondrial
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDADC1 cytidine and dCMP deaminase domain containing 1
CHM choroideremia (Rab escort protein 1)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEB cell death-inducing DFFA-like effector b
CISH cytokine inducible SH2-containing protein
CLIC3 chloride intracellular channel 3
CPZ carboxypeptidase Z
CSF1R colony stimulating factor 1 receptor
CTSF cathepsin F
CXORF56 chromosome X open reading frame 56
DBF4B DBF4 zinc finger B
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DNAH7 dynein, axonemal, heavy chain 7
EDIL3 EGF-like repeats and discoidin I-like domains 3
ERO1LB ERO1-like beta (S. cerevisiae)
EVPL envoplakin
EYA4 EYA transcriptional coactivator and phosphatase 4
FA2H fatty acid 2-hydroxylase
GAL3ST4 galactose-3-O-sulfotransferase 4
GAS8 growth arrest-specific 8
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GRAMD1C GRAM domain containing 1C
GRTP1 growth hormone regulated TBC protein 1
GSDMD gasdermin D
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H3G histone cluster 1, H3g
HIST2H2AA3 histone cluster 2, H2aa3
HPS6 Hermansky-Pudlak syndrome 6
HSPA1L heat shock 70kDa protein 1-like
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
INCENP inner centromere protein antigens 135/155kDa
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITPKA inositol-trisphosphate 3-kinase A
KLF2 Kruppel-like factor 2
KRT6A keratin 6A, type II
LIMS2 LIM and senescent cell antigen-like domains 2
LINC00597 long intergenic non-protein coding RNA 597
LMCD1 LIM and cysteine-rich domains 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGEF1 melanoma antigen family F1
MEGF8 multiple EGF-like-domains 8
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MN1 meningioma (disrupted in balanced translocation) 1
MOB3B MOB kinase activator 3B
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSBP2 oxysterol binding protein 2
PAIP2B poly(A) binding protein interacting protein 2B
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PCBP4 poly(rC) binding protein 4
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLH polymerase (DNA directed), eta
POM121 POM121 transmembrane nucleoporin
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAI2 retinoic acid induced 2
RNF126P1 ring finger protein 126 pseudogene 1
RUSC2 RUN and SH3 domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SCAMP5 secretory carrier membrane protein 5
SETBP1 SET binding protein 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SHPK sedoheptulokinase
TBC1D17 TBC1 domain family, member 17
THRAP3 thyroid hormone receptor associated protein 3
TMEM156 transmembrane protein 156
TMSB15A thymosin beta 15a
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TSPAN2 tetraspanin 2
TTLL7 tubulin tyrosine ligase-like family member 7
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP32 ubiquitin specific peptidase 32
VGF VGF nerve growth factor inducible
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF334 zinc finger protein 334
ZNF408 zinc finger protein 408
ZNF667 zinc finger protein 667
ZNF675 zinc finger protein 675