myasthenia gravis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_437)
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Genes

188 genes co-occuring with the disease myasthenia gravis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MUSK muscle, skeletal, receptor tyrosine kinase 3.07398
TTN titin 2.04146
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.0225
ACHE acetylcholinesterase (Yt blood group) 1.98343
BCHE butyrylcholinesterase 1.88944
RAPSN receptor-associated protein of the synapse 1.78308
CD4 CD4 molecule 1.69996
LRP4 low density lipoprotein receptor-related protein 4 1.69133
RYR1 ryanodine receptor 1 (skeletal) 1.59251
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.58314
OMG oligodendrocyte myelin glycoprotein 1.55336
DOK7 docking protein 7 1.50667
NMT1 N-myristoyltransferase 1 1.43069
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 1.4149
TMPO thymopoietin 1.31581
FOXP3 forkhead box P3 1.15837
AIRE autoimmune regulator 1.14178
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.14093
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 1.10468
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.08076
CST7 cystatin F (leukocystatin) 1.04672
AKAP12 A kinase (PRKA) anchor protein 12 1.02945
HLA-A major histocompatibility complex, class I, A 1.02861
TGFB1 transforming growth factor, beta 1 0.989379
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.980952
AQP4 aquaporin 4 0.959123
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.932898
POMC proopiomelanocortin 0.927932
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 0.860999
MBP myelin basic protein 0.852811
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.836837
CD79A CD79a molecule, immunoglobulin-associated alpha 0.825358
MB myoglobin 0.811001
IL2 interleukin 2 0.807308
IL4 interleukin 4 0.787213
CD5 CD5 molecule 0.774523
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.771661
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.758601
ALB albumin 0.75412
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 0.745172
IFNA1 interferon, alpha 1 0.739488
MAG myelin associated glycoprotein 0.735433
ADRA1D adrenoceptor alpha 1D 0.732596
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.683493
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.677903
CXCR5 chemokine (C-X-C motif) receptor 5 0.677504
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 0.676308
CXCL13 chemokine (C-X-C motif) ligand 13 0.667947
LTA lymphotoxin alpha 0.658026
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.637495
MYH13 myosin, heavy chain 13, skeletal muscle 0.635528
CD58 CD58 molecule 0.624927
CTSV cathepsin V 0.604981
HLA-B major histocompatibility complex, class I, B 0.603811
B3GAT1 beta-1,3-glucuronyltransferase 1 0.60225
CD19 CD19 molecule 0.6003
CCL21 chemokine (C-C motif) ligand 21 0.598351
DPYSL5 dihydropyrimidinase-like 5 0.592895
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.581996
HLA-C major histocompatibility complex, class I, C 0.572662
TNIP1 TNFAIP3 interacting protein 1 0.543155
CD86 CD86 molecule 0.536957
ARPC5L actin related protein 2/3 complex, subunit 5-like 0.523045
CAMP cathelicidin antimicrobial peptide 0.51534
CD80 CD80 molecule 0.501144
CHRND cholinergic receptor, nicotinic, delta (muscle) 0.499614
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.494648
CD59 CD59 molecule, complement regulatory protein 0.493122
IL1B interleukin 1, beta 0.490835
RPS13 ribosomal protein S13 0.48893
TNF tumor necrosis factor 0.482084
TSPO translocator protein (18kDa) 0.473361
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.468819
MYF6 myogenic factor 6 (herculin) 0.465794
CNTNAP2 contactin associated protein-like 2 0.462772
DYNLT1 dynein, light chain, Tctex-type 1 0.460506
IL10 interleukin 10 0.458241
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.457864
CHAT choline O-acetyltransferase 0.434899
NCAM1 neural cell adhesion molecule 1 0.432646
CD40LG CD40 ligand 0.429642
PRF1 perforin 1 (pore forming protein) 0.427015
PRSS16 protease, serine, 16 (thymus) 0.426265
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.42289
CD40 CD40 molecule, TNF receptor superfamily member 5 0.418394
CD69 CD69 molecule 0.415773
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.413901
TRAC T cell receptor alpha constant 0.407919
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.404184
MYOG myogenin (myogenic factor 4) 0.394863
SNED1 sushi, nidogen and EGF-like domains 1 0.394491
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.388909
AGRN agrin 0.384079
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.378885
LGI1 leucine-rich, glioma inactivated 1 0.377773
ADRB2 adrenoceptor beta 2, surface 0.37592
C5AR1 complement component 5a receptor 1 0.372217
SYT1 synaptotagmin I 0.367779
TG thyroglobulin 0.362239
CA3 carbonic anhydrase III 0.36187
VPREB1 pre-B lymphocyte 1 0.351555
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.349717
HSPG2 heparan sulfate proteoglycan 2 0.349717
PHYH phytanoyl-CoA 2-hydroxylase 0.348246
TCHH trichohyalin 0.342006
HLA-E major histocompatibility complex, class I, E 0.341639
MOG myelin oligodendrocyte glycoprotein 0.340173
MYOD1 myogenic differentiation 1 0.338341
TMX1 thioredoxin-related transmembrane protein 1 0.336144
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.330295
CD276 CD276 molecule 0.328105
GOLIM4 golgi integral membrane protein 4 0.320454
CIC capicua transcriptional repressor 0.316819
IGHV3-30 immunoglobulin heavy variable 3-30 0.315366
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.310652
ICAM1 intercellular adhesion molecule 1 0.307395
OAT ornithine aminotransferase 0.307395
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.305948
PTPRD protein tyrosine phosphatase, receptor type, D 0.299452
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 0.299092
IL7R interleukin 7 receptor 0.299092
AFP alpha-fetoprotein 0.296931
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.294413
AKAP1 A kinase (PRKA) anchor protein 1 0.294413
NRG4 neuregulin 4 0.29118
SIL1 SIL1 nucleotide exchange factor 0.287593
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.286519
AMPD1 adenosine monophosphate deaminase 1 0.284728
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.276158
C3 complement component 3 0.275445
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.273308
IL2RA interleukin 2 receptor, alpha 0.272597
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.268687
PANX2 pannexin 2 0.261952
PGA3 pepsinogen 3, group I (pepsinogen A) 0.261245
PGA4 pepsinogen 4, group I (pepsinogen A) 0.261245
BRDT bromodomain, testis-specific 0.25877
RND1 Rho family GTPase 1 0.258064
TSHR thyroid stimulating hormone receptor 0.257358
CLEC4C C-type lectin domain family 4, member C 0.254888
GFER growth factor, augmenter of liver regeneration 0.247852
WAC WW domain containing adaptor with coiled-coil 0.247501
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.237009
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.232489
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.231448
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.231102
PXDN peroxidasin 0.229024
SCO1 SCO1 cytochrome c oxidase assembly protein 0.225917
NELFCD negative elongation factor complex member C/D 0.222136
RBP3 retinol binding protein 3, interstitial 0.216332
STIM1 stromal interaction molecule 1 0.216332
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.214297
NRG2 neuregulin 2 0.213621
TPM1 tropomyosin 1 (alpha) 0.213283
TFRC transferrin receptor 0.212271
PTPRC protein tyrosine phosphatase, receptor type, C 0.209248
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.207245
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.206913
NLE1 notchless homolog 1 (Drosophila) 0.205916
TUBB2A tubulin, beta 2A class IIa 0.198709
MBD5 methyl-CpG binding domain protein 5 0.193915
F8 coagulation factor VIII, procoagulant component 0.193285
MRPS7 mitochondrial ribosomal protein S7 0.186811
CXCR3 chemokine (C-X-C motif) receptor 3 0.18651
CTTN cortactin 0.185612
CENPC centromere protein C 0.182086
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.181798
C4A complement component 4A (Rodgers blood group) 0.180652
ADA adenosine deaminase 0.17952
MIR185 microRNA 185 0.178126
CNTFR ciliary neurotrophic factor receptor 0.177851
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.175947
CNTN2 contactin 2 (axonal) 0.174354
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.173832
CD52 CD52 molecule 0.170299
TUBB tubulin, beta class I 0.170299
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.168381
CIITA class II, major histocompatibility complex, transactivator 0.168148
SRPR signal recognition particle receptor (docking protein) 0.165655
IL17A interleukin 17A 0.165435
IGHV3-9 immunoglobulin heavy variable 3-9 0.164786
NUMBL numb homolog (Drosophila)-like 0.164149
BAG6 BCL2-associated athanogene 6 0.160761
IFNB1 interferon, beta 1, fibroblast 0.159658
MTX1 metaxin 1 0.158951
IGLV9-49 immunoglobulin lambda variable 9-49 0.158434
BIN3 bridging integrator 3 0.158266
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.14359