mutlalpha complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2. (Gene Ontology, GO_0032389)
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43 proteins co-occuring with the mutlalpha complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.80215
MLH1 mutL homolog 1 2.50819
MSH2 mutS homolog 2 2.09765
MSH6 mutS homolog 6 1.87658
MLH3 mutL homolog 3 1.47287
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 1.36197
EXO1 exonuclease 1 1.19674
DTX2 deltex 2, E3 ubiquitin ligase 1.06347
CCDC26 CCDC26 long non-coding RNA 1.00596
GH2 growth hormone 2 0.969366
TLE6 transducin-like enhancer of split 6 0.900426
PHLDB1 pleckstrin homology-like domain, family B, member 1 0.887936
PCNA proliferating cell nuclear antigen 0.830466
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 0.703949
RFC3 replication factor C (activator 1) 3, 38kDa 0.662935
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.660345
RFC4 replication factor C (activator 1) 4, 37kDa 0.65905
RFC1 replication factor C (activator 1) 1, 145kDa 0.638005
GH1 growth hormone 1 0.63715
RFC2 replication factor C (activator 1) 2, 40kDa 0.60444
CHEK1 checkpoint kinase 1 0.544823
NOTO notochord homeobox 0.415728
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.397811
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.386208
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.364713
POLH polymerase (DNA directed), eta 0.344935
MSH3 mutS homolog 3 0.341529
MUTYH mutY homolog 0.338884
CLSPN claspin 0.31596
HUS1 HUS1 checkpoint homolog (S. pombe) 0.299569
BRCA1 breast cancer 1, early onset 0.296972
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.275936
RAD17 RAD17 homolog (S. pombe) 0.275202
BRCA2 breast cancer 2, early onset 0.269335
RUNX3 runt-related transcription factor 3 0.262025
KRAS Kirsten rat sarcoma viral oncogene homolog 0.26166
RAD9A RAD9 homolog A (S. pombe) 0.244962
HMGB1 high mobility group box 1 0.206423
TOPBP1 topoisomerase (DNA) II binding protein 1 0.205059
ERCC4 excision repair cross-complementation group 4 0.201672
TSC1 tuberous sclerosis 1 0.186397
HRAS Harvey rat sarcoma viral oncogene homolog 0.170629
CFH complement factor H 0.161693