muscular coat Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description An outer layer of smooth muscle surrounding a hollow or tubular organ as the bladder, esophagus, large intestine, small intestine, stomach, ureter, uterus, and vagina that often consists of an inner layer of circular fibers serving to narrow the lumen of the organ and an outer layer of longitudinal fibers serving to shorten its length. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004838)
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Genes

226 proteins co-occuring with the tissue muscular coat in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
TAC1 tachykinin, precursor 1 1.89876
VIP vasoactive intestinal peptide 1.88218
GUCY2C guanylate cyclase 2C 1.38596
NPR1 natriuretic peptide receptor 1 1.38322
NTS neurotensin 1.335
CDK5RAP1 CDK5 regulatory subunit associated protein 1 1.28726
TACR2 tachykinin receptor 2 1.28233
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 1.25012
NPY neuropeptide Y 1.10579
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 1.07971
MLN motilin 1.07883
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.06647
MRGPRF MAS-related GPR, member F 1.03302
GRP gastrin-releasing peptide 1.03214
TACR1 tachykinin receptor 1 1.012
CALCA calcitonin-related polypeptide alpha 0.983688
DNAH8 dynein, axonemal, heavy chain 8 0.929335
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.926336
NPS neuropeptide S 0.901573
MRGPRE MAS-related GPR, member E 0.891798
CCK cholecystokinin 0.884591
SST somatostatin 0.882051
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.862206
TAS2R10 taste receptor, type 2, member 10 0.861785
CHAT choline O-acetyltransferase 0.826942
KNG1 kininogen 1 0.826942
SOCS2 suppressor of cytokine signaling 2 0.806465
ACHE acetylcholinesterase (Yt blood group) 0.793543
GAST gastrin 0.775249
MLNR motilin receptor 0.765296
SCN5A sodium channel, voltage gated, type V alpha subunit 0.758673
MYLK myosin light chain kinase 0.756604
TACR3 tachykinin receptor 3 0.741327
GAL galanin/GMAP prepropeptide 0.73062
MYLK3 myosin light chain kinase 3 0.703127
ADRB3 adrenoceptor beta 3 0.692902
PYY peptide YY 0.691268
CSN3 casein kappa 0.67984
CNOT2 CCR4-NOT transcription complex, subunit 2 0.671692
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.671285
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.668843
GJA1 gap junction protein, alpha 1, 43kDa 0.666809
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 0.65746
SCN3B sodium channel, voltage gated, type III beta subunit 0.648938
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.646505
CNR1 cannabinoid receptor 1 (brain) 0.62991
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.627889
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.627485
NPPC natriuretic peptide C 0.62385
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.618603
IL12A interleukin 12A 0.614571
TAC3 tachykinin 3 0.590036
ADCY2 adenylate cyclase 2 (brain) 0.587629
PTGR1 prostaglandin reductase 1 0.587228
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.586828
EDNRA endothelin receptor type A 0.578016
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.573217
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.571219
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.570021
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.570021
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.568823
HMOX2 heme oxygenase 2 0.565631
BARX2 BARX homeobox 2 0.562042
MRVI1 murine retrovirus integration site 1 homolog 0.560847
INSL6 insulin-like 6 0.560449
ENO2 enolase 2 (gamma, neuronal) 0.551298
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.549312
MPO myeloperoxidase 0.531089
CCKAR cholecystokinin A receptor 0.529508
STOM stomatin 0.526744
EDN1 endothelin 1 0.52635
OPRD1 opioid receptor, delta 1 0.520041
CASS4 Cas scaffolding protein family member 4 0.515317
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.510599
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.49844
ETHE1 ethylmalonic encephalopathy 1 0.494528
IGF1 insulin-like growth factor 1 (somatomedin C) 0.480091
NMU neuromedin U 0.472704
HPD 4-hydroxyphenylpyruvate dioxygenase 0.465723
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.461465
PDE5A phosphodiesterase 5A, cGMP-specific 0.455284
PPP6C protein phosphatase 6, catalytic subunit 0.454512
ADM adrenomedullin 0.454126
SYP synaptophysin 0.450271
PPP5C protein phosphatase 5, catalytic subunit 0.446422
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.445268
DAPK3 death-associated protein kinase 3 0.442962
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.44181
NKX3-1 NK3 homeobox 1 0.432225
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.430695
RND2 Rho family GTPase 2 0.42993
ADRA1D adrenoceptor alpha 1D 0.429165
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.428783
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.428018
EDN2 endothelin 2 0.427254
TUBE1 tubulin, epsilon 1 0.418099
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.414293
RBMS1 RNA binding motif, single stranded interacting protein 1 0.413912
PLA2G5 phospholipase A2, group V 0.405555
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.405176
IGFBP5 insulin-like growth factor binding protein 5 0.404039
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.402144
HRH3 histamine receptor H3 0.397979
BHLHE22 basic helix-loop-helix family, member e22 0.396844
TH tyrosine hydroxylase 0.393819
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.391176
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.390044
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.388158
NT5E 5'-nucleotidase, ecto (CD73) 0.387027
BCHE butyrylcholinesterase 0.385143
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.38439
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 0.377996
CRYGD crystallin, gamma D 0.377996
ANO1 anoctamin 1, calcium activated chloride channel 0.376494
GJB6 gap junction protein, beta 6, 30kDa 0.375368
CHRM2 cholinergic receptor, muscarinic 2 0.371619
HDAC4 histone deacetylase 4 0.370121
PPP4C protein phosphatase 4, catalytic subunit 0.366007
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.364513
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.355942
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.335968
MMEL1 membrane metallo-endopeptidase-like 1 0.334865
TEF thyrotrophic embryonic factor 0.333763
LAP3 leucine aminopeptidase 3 0.333396
IL1B interleukin 1, beta 0.330094
ADRA1A adrenoceptor alpha 1A 0.328262
GIP gastric inhibitory polypeptide 0.327896
MYH11 myosin, heavy chain 11, smooth muscle 0.323509
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.323509
CSK c-src tyrosine kinase 0.322414
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 0.322414
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.315861
CRHR2 corticotropin releasing hormone receptor 2 0.314046
CAMP cathelicidin antimicrobial peptide 0.31332
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.312595
NLE1 notchless homolog 1 (Drosophila) 0.312595
LAMA5 laminin, alpha 5 0.311507
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.310783
PLN phospholamban 0.307167
OXTR oxytocin receptor 0.305722
PLA2G1B phospholipase A2, group IB (pancreas) 0.300679
BRS3 bombesin-like receptor 3 0.297447
TBXA2R thromboxane A2 receptor 0.294223
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.293866
RND3 Rho family GTPase 3 0.290295
CCL2 chemokine (C-C motif) ligand 2 0.280364
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.276846
GLP1R glucagon-like peptide 1 receptor 0.270561
NPPA natriuretic peptide A 0.261964
HOXA4 homeobox A4 0.260267
IL6 interleukin 6 0.254239
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.253578
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.253578
KLF9 Kruppel-like factor 9 0.251606
TLR4 toll-like receptor 4 0.250953
PNN pinin, desmosome associated protein 0.250953
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.249977
KMT2A lysine (K)-specific methyltransferase 2A 0.249653
F2R coagulation factor II (thrombin) receptor 0.245491
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 0.24486
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.240216
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 0.234016
PDZK1IP1 PDZK1 interacting protein 1 0.233446
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 0.224398
ATP11A ATPase, class VI, type 11A 0.224398
ICAM1 intercellular adhesion molecule 1 0.223177
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.220831
ADRB1 adrenoceptor beta 1 0.219707
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.218186
GDNF glial cell derived neurotrophic factor 0.217762
ALB albumin 0.217139
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.215994
ACTG2 actin, gamma 2, smooth muscle, enteric 0.214202
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.21365
CLDN11 claudin 11 0.197423
IL17C interleukin 17C 0.192054
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.191909
LXN latexin 0.191739
MLYCD malonyl-CoA decarboxylase 0.191705
HM13 histocompatibility (minor) 13 0.191509
SCTR secretin receptor 0.191391
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.190846
NANP N-acetylneuraminic acid phosphatase 0.190505
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 0.190205
KEL Kell blood group, metallo-endopeptidase 0.190099
HSH2D hematopoietic SH2 domain containing 0.190005
RXFP1 relaxin/insulin-like family peptide receptor 1 0.189992
PRKG1 protein kinase, cGMP-dependent, type I 0.189924
FLOT1 flotillin 1 0.189705
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.189691
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 0.189339
NKX2-5 NK2 homeobox 5 0.18899
ASPA aspartoacylase 0.188946
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.188445
ASL argininosuccinate lyase 0.18832
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.188131
ANPEP alanyl (membrane) aminopeptidase 0.187937
HRH1 histamine receptor H1 0.187937
PDYN prodynorphin 0.187741
ADRB2 adrenoceptor beta 2, surface 0.187691
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.187675
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.187423
MARK3 MAP/microtubule affinity-regulating kinase 3 0.187078
BDKRB1 bradykinin receptor B1 0.186613
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 0.186448
GSN gelsolin 0.186243
IFITM1 interferon induced transmembrane protein 1 0.185724
THOP1 thimet oligopeptidase 1 0.185445
ARF1 ADP-ribosylation factor 1 0.185384
DLG1 discs, large homolog 1 (Drosophila) 0.184972
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.184909
TRPC5 transient receptor potential cation channel, subfamily C, member 5 0.184436
RIPK4 receptor-interacting serine-threonine kinase 4 0.184369
LMNB1 lamin B1 0.183943
PTK7 protein tyrosine kinase 7 (inactive) 0.183919
S100G S100 calcium binding protein G 0.18277
GCGR glucagon receptor 0.182284
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 0.181806
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.181477
SCN3A sodium channel, voltage gated, type III alpha subunit 0.181477
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.180939
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.180852
ASS1 argininosuccinate synthase 1 0.180793
NPR3 natriuretic peptide receptor 3 0.180134
SCN2A sodium channel, voltage gated, type II alpha subunit 0.180134
PAEP progestagen-associated endometrial protein 0.179665