mtor signaling pathway Gene Set

Dataset KEGG Pathways
Category structural or functional annotations
Type pathway
Description mTOR signaling pathway regulates cellular processes such as translation, ribosome biogenesis, cell growth and autophagy and is regulated or responds to growth factors, energy metabolites and/or levels of nutrients. (Pathway Ontology, PW_0000180)
External Link http://www.genome.jp/kegg/pathway/hsa/hsa04150.html
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Genes

44 proteins participating in the mtor signaling pathway pathway from the KEGG Pathways dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
CAB39 calcium binding protein 39
DDIT4 DNA-damage-inducible transcript 4
EIF4B eukaryotic translation initiation factor 4B
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IGF1 insulin-like growth factor 1 (somatomedin C)
INS insulin
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
PDPK1 3-phosphoinositide dependent protein kinase 1
PGF placental growth factor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
RHEB Ras homolog enriched in brain
RICTOR RPTOR independent companion of MTOR, complex 2
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
STK11 serine/threonine kinase 11
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
ULK1 unc-51 like autophagy activating kinase 1
ULK2 unc-51 like autophagy activating kinase 2
ULK3 unc-51 like kinase 3
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C