mre11 complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins. (Gene Ontology, GO_0030870)
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3 proteins localized to the mre11 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NBN nibrin 0.663342
RAD50 RAD50 homolog (S. cerevisiae) 0.663342
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.237908