motile cilium Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A cilium which has a variable arrangement of axonemal microtubules, contains molecular motors, and beats with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface. Motile cilia are typically found in multiple copies on epithelial cells that line the lumenal ducts of various tissues. Motile cilia may also function as sensory organelles. (Gene Ontology, GO_0031514)
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Genes

353 proteins co-occuring with the motile cilium cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
FOXJ1 forkhead box J1 1.97557
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 1.30981
DNAH9 dynein, axonemal, heavy chain 9 1.29531
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.26234
CCDC39 coiled-coil domain containing 39 1.2179
DNAH5 dynein, axonemal, heavy chain 5 1.19417
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.19263
CEP290 centrosomal protein 290kDa 1.15825
BBS7 Bardet-Biedl syndrome 7 1.13523
RAB8A RAB8A, member RAS oncogene family 1.12807
SPAG16 sperm associated antigen 16 1.12296
SPEF2 sperm flagellar 2 1.10817
LRRC6 leucine rich repeat containing 6 1.09442
B9D1 B9 protein domain 1 1.08577
CCDC65 coiled-coil domain containing 65 1.0569
DNAI1 dynein, axonemal, intermediate chain 1 1.05287
SPAG6 sperm associated antigen 6 1.03529
ARL13B ADP-ribosylation factor-like 13B 1.03279
RPGR retinitis pigmentosa GTPase regulator 1.0258
NPHP4 nephronophthisis 4 1.02082
BBS5 Bardet-Biedl syndrome 5 1.01536
BBS4 Bardet-Biedl syndrome 4 1.01536
PKD1L1 polycystic kidney disease 1 like 1 1.01387
AKAP3 A kinase (PRKA) anchor protein 3 1.01189
IFT20 intraflagellar transport 20 1.0109
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 1.0109
TCTN1 tectonic family member 1 1.00843
STK36 serine/threonine kinase 36 1.00202
TMEM231 transmembrane protein 231 0.999068
RPGRIP1L RPGRIP1-like 0.993183
CC2D2A coiled-coil and C2 domain containing 2A 0.987806
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 0.98683
DNAH11 dynein, axonemal, heavy chain 11 0.970814
B9D2 B9 protein domain 2 0.96503
LPIN3 lipin 3 0.960707
DNAAF1 dynein, axonemal, assembly factor 1 0.956395
INVS inversin 0.949236
DNAI2 dynein, axonemal, intermediate chain 2 0.947808
BBS1 Bardet-Biedl syndrome 1 0.946382
CCDC40 coiled-coil domain containing 40 0.942584
RHO rhodopsin 0.94211
DNAAF5 dynein, axonemal, assembly factor 5 0.940215
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 0.937377
RFX7 regulatory factor X, 7 0.930774
SSTR3 somatostatin receptor 3 0.917177
ARL6 ADP-ribosylation factor-like 6 0.909251
TCTN2 tectonic family member 2 0.902745
IFT88 intraflagellar transport 88 0.901353
GUCY2C guanylate cyclase 2C 0.90089
SPA17 sperm autoantigenic protein 17 0.897646
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 0.897646
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16 0.897646
RFX3 regulatory factor X, 3 (influences HLA class II expression) 0.89348
MKS1 Meckel syndrome, type 1 0.892093
NPR1 natriuretic peptide receptor 1 0.891169
SHH sonic hedgehog 0.890707
TTC8 tetratricopeptide repeat domain 8 0.887936
CFAP97 cilia and flagella associated protein 97 0.883321
RSPH1 radial spoke head 1 homolog (Chlamydomonas) 0.875488
TUBA1A tubulin, alpha 1a 0.871346
KIF27 kinesin family member 27 0.869046
GAS8 growth arrest-specific 8 0.868126
IFT52 intraflagellar transport 52 0.863988
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.86077
HYDIN HYDIN, axonemal central pair apparatus protein 0.856176
DNAAF2 dynein, axonemal, assembly factor 2 0.852961
CEP164 centrosomal protein 164kDa 0.849287
APOPT1 apoptogenic 1, mitochondrial 0.843318
RSPH3 radial spoke 3 homolog (Chlamydomonas) 0.828171
ARL3 ADP-ribosylation factor-like 3 0.823582
PACRG PARK2 co-regulated 0.82037
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.819452
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.819452
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.818993
TTBK2 tau tubulin kinase 2 0.802938
USMG5 up-regulated during skeletal muscle growth 5 homolog (mouse) 0.795145
KATNAL2 katanin p60 subunit A-like 2 0.795145
BBS2 Bardet-Biedl syndrome 2 0.783241
SMO smoothened, frizzled class receptor 0.778669
AKAP14 A kinase (PRKA) anchor protein 14 0.764982
IQCB1 IQ motif containing B1 0.758161
ACPP acid phosphatase, prostate 0.758161
C2CD3 C2 calcium-dependent domain containing 3 0.750904
SNTN sentan, cilia apical structure protein 0.742318
CCNO cyclin O 0.738713
DAW1 dynein assembly factor with WDR repeat domains 1 0.736913
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.736464
BBS12 Bardet-Biedl syndrome 12 0.735115
NME8 NME/NM23 family member 8 0.735115
TF transferrin 0.734217
NPHP1 nephronophthisis 1 (juvenile) 0.729732
KIAA0586 KIAA0586 0.726152
DYX1C1 dyslexia susceptibility 1 candidate 1 0.720797
C15ORF26 chromosome 15 open reading frame 26 0.715902
ULK4 unc-51 like kinase 4 0.71457
TTC25 tetratricopeptide repeat domain 25 0.711465
TMEM216 transmembrane protein 216 0.710579
TCTN3 tectonic family member 3 0.706598
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 0.705273
NME7 NME/NM23 family member 7 0.704831
DNAH14 dynein, axonemal, heavy chain 14 0.704831
DNAH12 dynein, axonemal, heavy chain 12 0.704831
KIF17 kinesin family member 17 0.701744
SPAG17 sperm associated antigen 17 0.699983
TTLL6 tubulin tyrosine ligase-like family member 6 0.699103
DZIP1L DAZ interacting zinc finger protein 1-like 0.69164
SLC26A8 solute carrier family 26 (anion exchanger), member 8 0.690326
CATSPERB catsper channel auxiliary subunit beta 0.689451
CATSPERG catsper channel auxiliary subunit gamma 0.689013
PRICKLE2 prickle homolog 2 (Drosophila) 0.687701
IFT172 intraflagellar transport 172 0.685954
LCA5 Leber congenital amaurosis 5 0.684644
AKAP4 A kinase (PRKA) anchor protein 4 0.684644
GLI3 GLI family zinc finger 3 0.678108
MNS1 meiosis-specific nuclear structural 1 0.669425
CEP131 centrosomal protein 131kDa 0.667693
DNAH8 dynein, axonemal, heavy chain 8 0.662072
SPEF1 sperm flagellar 1 0.656033
ROPN1 rhophilin associated tail protein 1 0.651299
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.647862
UNC119B unc-119 homolog B (C. elegans) 0.647433
TRAPPC3 trafficking protein particle complex 3 0.645716
DNAH7 dynein, axonemal, heavy chain 7 0.643572
ANAPC2 anaphase promoting complex subunit 2 0.635868
RCVRN recoverin 0.631598
DNAH10 dynein, axonemal, heavy chain 10 0.628613
DRC7 dynein regulatory complex subunit 7 0.624781
TTC29 tetratricopeptide repeat domain 29 0.622229
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 0.621804
INMT indolethylamine N-methyltransferase 0.621379
MCHR1 melanin-concentrating hormone receptor 1 0.611625
TBC1D32 TBC1 domain family, member 32 0.609509
TTLL8 tubulin tyrosine ligase-like family member 8 0.605284
TMEM67 transmembrane protein 67 0.60444
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 0.600223
CEP162 centrosomal protein 162kDa 0.600223
OFD1 oral-facial-digital syndrome 1 0.599802
VIPR2 vasoactive intestinal peptide receptor 2 0.593912
TMEM237 transmembrane protein 237 0.592232
IFT46 intraflagellar transport 46 0.591392
CEP41 centrosomal protein 41kDa 0.590553
UNC119 unc-119 homolog (C. elegans) 0.588456
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1 0.588037
ZMYND10 zinc finger, MYND-type containing 10 0.585523
ULK3 unc-51 like kinase 3 0.582594
CCDC78 coiled-coil domain containing 78 0.58134
TPGS1 tubulin polyglutamylase complex subunit 1 0.578833
TBPL1 TBP-like 1 0.575078
NME5 NME/NM23 family member 5 0.572578
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 0.569664
NPHP3 nephronophthisis 3 (adolescent) 0.567169
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 0.562187
COBL cordon-bleu WH2 repeat protein 0.560114
SEPT2 septin 2 0.558871
DZIP1 DAZ interacting zinc finger protein 1 0.556387
NPFFR2 neuropeptide FF receptor 2 0.556387
GLI1 GLI family zinc finger 1 0.555973
SFXN2 sideroflexin 2 0.555973
RILPL1 Rab interacting lysosomal protein-like 1 0.552664
IGHV1-2 immunoglobulin heavy variable 1-2 0.552251
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.549773
TTC26 tetratricopeptide repeat domain 26 0.54936
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 0.548947
RFX4 regulatory factor X, 4 (influences HLA class II expression) 0.541117
GLI2 GLI family zinc finger 2 0.536183
VANGL2 VANGL planar cell polarity protein 2 0.535361
LEFTY2 left-right determination factor 2 0.533719
CNTLN centlein, centrosomal protein 0.531668
GUCA1B guanylate cyclase activator 1B (retina) 0.52675
IFT22 intraflagellar transport 22 0.519389
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.517348
PPP1R7 protein phosphatase 1, regulatory subunit 7 0.504724
KIF3A kinesin family member 3A 0.504318
IFT57 intraflagellar transport 57 0.500664
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 0.498231
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.49661
TFRC transferrin receptor 0.495395
PCNT pericentrin 0.491348
ARF4 ADP-ribosylation factor 4 0.484886
ANO2 anoctamin 2, calcium activated chloride channel 0.481661
CCDC114 coiled-coil domain containing 114 0.480453
FAM161B family with sequence similarity 161, member B 0.476429
AKAP1 A kinase (PRKA) anchor protein 1 0.473617
SEPT7P2 septin 7 pseudogene 2 0.470406
PRPH2 peripherin 2 (retinal degeneration, slow) 0.464798
S100A5 S100 calcium binding protein A5 0.460401
CCDC151 coiled-coil domain containing 151 0.460401
KCNU1 potassium channel, subfamily U, member 1 0.454816
TBCCD1 TBCC domain containing 1 0.452825
ARTN artemin 0.451233
CROCC ciliary rootlet coiled-coil, rootletin 0.448848
SNX10 sorting nexin 10 0.446862
BBS10 Bardet-Biedl syndrome 10 0.444878
AGTPBP1 ATP/GTP binding protein 1 0.444085
ARMC4 armadillo repeat containing 4 0.443292
NEK4 NIMA-related kinase 4 0.438937
TRAPPC8 trafficking protein particle complex 8 0.436565
SCLT1 sodium channel and clathrin linker 1 0.432224
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.432224
CEP135 centrosomal protein 135kDa 0.428284
ODF2 outer dense fiber of sperm tails 2 0.421604
RGS9 regulator of G-protein signaling 9 0.417294
DCDC2 doublecortin domain containing 2 0.416902
MCHR2 melanin-concentrating hormone receptor 2 0.416511
NUBP1 nucleotide binding protein 1 0.41612
GOLGB1 golgin B1 0.415728
RILPL2 Rab interacting lysosomal protein-like 2 0.415728
CEP83 centrosomal protein 83kDa 0.409479
THEMIS thymocyte selection associated 0.408309
NUBP2 nucleotide binding protein 2 0.397423
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 0.397423
NUDC nudC nuclear distribution protein 0.395485
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 0.395485
SEPT5 septin 5 0.391615
CATSPER1 cation channel, sperm associated 1 0.390455
STARD6 StAR-related lipid transfer (START) domain containing 6 0.387751
DNALI1 dynein, axonemal, light intermediate chain 1 0.387365
FUZ fuzzy planar cell polarity protein 0.385436
WDR34 WD repeat domain 34 0.385436
JADE1 jade family PHD finger 1 0.38428
FAM161A family with sequence similarity 161, member A 0.381969
AKAP11 A kinase (PRKA) anchor protein 11 0.378122
CEP70 centrosomal protein 70kDa 0.37697
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 0.375818
STK38L serine/threonine kinase 38 like 0.374283
RFX2 regulatory factor X, 2 (influences HLA class II expression) 0.356705
FTL ferritin, light polypeptide 0.355563
KIZ kizuna centrosomal protein 0.354802
FTH1 ferritin, heavy polypeptide 1 0.353662
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.351762
MSH6 mutS homolog 6 0.351762
SDCCAG8 serologically defined colon cancer antigen 8 0.351762
GCA grancalcin, EF-hand calcium binding protein 0.351382
BBS9 Bardet-Biedl syndrome 9 0.349105
KIAA0319 KIAA0319 0.343421
PAQR7 progestin and adipoQ receptor family member VII 0.340017
RGS9BP regulator of G protein signaling 9 binding protein 0.336996
CEP170 centrosomal protein 170kDa 0.336241
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.332095
NPR2 natriuretic peptide receptor 2 0.330213
CEP97 centrosomal protein 97kDa 0.327956
PLEKHN1 pleckstrin homology domain containing, family N member 1 0.327205
EVC2 Ellis van Creveld syndrome 2 0.327205
CNTN1 contactin 1 0.325327
LHX1 LIM homeobox 1 0.323075
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 0.313718
SEPT12 septin 12 0.313344
TTL tubulin tyrosine ligase 0.312224
FBF1 Fas (TNFRSF6) binding factor 1 0.309986
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.307377
EXOC6 exocyst complex component 6 0.305143
AK7 adenylate kinase 7 0.303655
FTMT ferritin mitochondrial 0.302912
CEP63 centrosomal protein 63kDa 0.302168
NOTCH1 notch 1 0.302168
S100A1 S100 calcium binding protein A1 0.289199
PDC phosducin 0.286983
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 0.286245
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.285876
USP9X ubiquitin specific peptidase 9, X-linked 0.285138
DVL1 dishevelled segment polarity protein 1 0.27998
RAB10 RAB10, member RAS oncogene family 0.279245
IFT80 intraflagellar transport 80 0.278509
IFT140 intraflagellar transport 140 0.276304
ROM1 retinal outer segment membrane protein 1 0.274835
RAB8B RAB8B, member RAS oncogene family 0.272267
AHI1 Abelson helper integration site 1 0.272267
LMLN leishmanolysin-like (metallopeptidase M8 family) 0.269335
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.265311
PRICKLE1 prickle homolog 1 (Drosophila) 0.260931
ALMS1 Alstrom syndrome protein 1 0.260566
ALB albumin 0.258381
LGALS13 lectin, galactoside-binding, soluble, 13 0.258016
TMPRSS13 transmembrane protease, serine 13 0.257652
ZIC2 Zic family member 2 0.25547
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.255107
SCD5 stearoyl-CoA desaturase 5 0.252564
VANGL1 VANGL planar cell polarity protein 1 0.252202
KLC3 kinesin light chain 3 0.251839
LAP3 leucine aminopeptidase 3 0.251476
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.249664
PHF12 PHD finger protein 12 0.248216
WDR19 WD repeat domain 19 0.243879
MGAM maltase-glucoamylase 0.242437
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.242437
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.241356
TUBA4A tubulin, alpha 4a 0.240996
ANXA1 annexin A1 0.239197
TUBD1 tubulin, delta 1 0.237401
CNR1 cannabinoid receptor 1 (brain) 0.236324
SLC51A solute carrier family 51, alpha subunit 0.234174
EFHC1 EF-hand domain (C-terminal) containing 1 0.233817
EVC Ellis van Creveld protein 0.233817
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.230958
RAB5C RAB5C, member RAS oncogene family 0.228464
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.225622
FRMD6 FERM domain containing 6 0.221025
RAB28 RAB28, member RAS oncogene family 0.220673
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.214714
CRNN cornulin 0.210203
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 0.210203
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.209686
HDAC6 histone deacetylase 6 0.208481
TRIM10 tripartite motif containing 10 0.206766
MARK4 MAP/microtubule affinity-regulating kinase 4 0.204039
GRK5 G protein-coupled receptor kinase 5 0.203361
FNDC3A fibronectin type III domain containing 3A 0.202346
TRIM26 tripartite motif containing 26 0.202009
S100B S100 calcium binding protein B 0.197993
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.196339
TRIM15 tripartite motif containing 15 0.193394
PARD3 par-3 family cell polarity regulator 0.19307
CDKN2A cyclin-dependent kinase inhibitor 2A 0.19307
SEPT7 septin 7 0.192423
SNED1 sushi, nidogen and EGF-like domains 1 0.187333
RAB23 RAB23, member RAS oncogene family 0.186708
ADCY2 adenylate cyclase 2 (brain) 0.186397
DNM2 dynamin 2 0.181823
AK2 adenylate kinase 2 0.181375
NEK1 NIMA-related kinase 1 0.180339
HYLS1 hydrolethalus syndrome 1 0.178588
FOXP2 forkhead box P2 0.173003
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.17141
DFNB31 deafness, autosomal recessive 31 0.168598
SNORA29 small nucleolar RNA, H/ACA box 29 0.168598
TRIP11 thyroid hormone receptor interactor 11 0.167856
FZD6 frizzled class receptor 6 0.166884
RAB11A RAB11A, member RAS oncogene family 0.166405
CDK20 cyclin-dependent kinase 20 0.165
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.164315
INSR insulin receptor 0.161068
SUFU suppressor of fused homolog (Drosophila) 0.161068
GABARAPL1 GABA(A) receptor-associated protein like 1 0.160254
LDB3 LIM domain binding 3 0.158502
FLCN folliculin 0.158502
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.158315
PTOV1 prostate tumor overexpressed 1 0.157578
HAS2 hyaluronan synthase 2 0.150736
RAPSN receptor-associated protein of the synapse 0.147085
AK1 adenylate kinase 1 0.144942
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.142487
TJP2 tight junction protein 2 0.142089
HAS1 hyaluronan synthase 1 0.141664
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.140995
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.13977
GPX4 glutathione peroxidase 4 0.138902
SHBG sex hormone-binding globulin 0.138445
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.1381
CDSN corneodesmosin 0.137856
VCL vinculin 0.137442
ACO2 aconitase 2, mitochondrial 0.137401
SREBF1 sterol regulatory element binding transcription factor 1 0.13695
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.136276