monorden-2679 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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193 genes differentially expressed following the monorden-2679 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
ANG angiogenin, ribonuclease, RNase A family, 5
ANXA1 annexin A1
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APP amyloid beta (A4) precursor protein
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
B9D2 B9 protein domain 2
BAG3 BCL2-associated athanogene 3
BLZF1 basic leucine zipper nuclear factor 1
BST2 bone marrow stromal cell antigen 2
C3ORF14 chromosome 3 open reading frame 14
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CAPN2 calpain 2, (m/II) large subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCNG2 cyclin G2
CD47 CD47 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD84 CD84 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP135 centrosomal protein 135kDa
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
COL4A2 collagen, type IV, alpha 2
CREBZF CREB/ATF bZIP transcription factor
CRYZ crystallin, zeta (quinone reductase)
CUL7 cullin 7
DBT dihydrolipoamide branched chain transacylase E2
DGKE diacylglycerol kinase, epsilon 64kDa
DGKG diacylglycerol kinase, gamma 90kDa
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EED embryonic ectoderm development
ENGASE endo-beta-N-acetylglucosaminidase
ENO2 enolase 2 (gamma, neuronal)
EPHB2 EPH receptor B2
FAM13A family with sequence similarity 13, member A
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
GALC galactosylceramidase
GAST gastrin
GUSBP3 glucuronidase, beta pseudogene 3
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HLA-F major histocompatibility complex, class I, F
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HRH1 histamine receptor H1
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IDS iduronate 2-sulfatase
IGL immunoglobulin lambda locus
IL10RA interleukin 10 receptor, alpha
IL1R1 interleukin 1 receptor, type I
KANSL1L KAT8 regulatory NSL complex subunit 1-like
MBNL2 muscleblind-like splicing regulator 2
MBOAT7 membrane bound O-acyltransferase domain containing 7
MICB MHC class I polypeptide-related sequence B
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTMR4 myotubularin related protein 4
MTUS1 microtubule associated tumor suppressor 1
NPC1 Niemann-Pick disease, type C1
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM5 PDZ and LIM domain 5
PHACTR1 phosphatase and actin regulator 1
PHTF1 putative homeodomain transcription factor 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMP22 peripheral myelin protein 22
PPID peptidylprolyl isomerase D
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRMT2 protein arginine methyltransferase 2
RASAL2 RAS protein activator like 2
RIT1 Ras-like without CAAX 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCARB2 scavenger receptor class B, member 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SPATS2L spermatogenesis associated, serine-rich 2-like
SRSF5 serine/arginine-rich splicing factor 5
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STIP1 stress-induced phosphoprotein 1
STON1 stonin 1
TGFBR3 transforming growth factor, beta receptor III
THBS1 thrombospondin 1
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
ULBP2 UL16 binding protein 2
VPS9D1 VPS9 domain containing 1
ZBTB38 zinc finger and BTB domain containing 38
ZFHX3 zinc finger homeobox 3
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
APOC4 apolipoprotein C-IV
ATP13A2 ATPase type 13A2
AXIN1 axin 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAMBI BMP and activin membrane-bound inhibitor
BANK1 B-cell scaffold protein with ankyrin repeats 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCAS3 breast carcinoma amplified sequence 3
C10ORF2 chromosome 10 open reading frame 2
C16ORF59 chromosome 16 open reading frame 59
C19ORF73 chromosome 19 open reading frame 73
C21ORF91 chromosome 21 open reading frame 91
CCDC106 coiled-coil domain containing 106
CCDC86 coiled-coil domain containing 86
CCL27 chemokine (C-C motif) ligand 27
CD160 CD160 molecule
CD34 CD34 molecule
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN2 chloride channel, voltage-sensitive 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDN dendrin
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DHRS11 dehydrogenase/reductase (SDR family) member 11
DOCK5 dedicator of cytokinesis 5
DSCAM Down syndrome cell adhesion molecule
E2F1 E2F transcription factor 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFCAB2 EF-hand calcium binding domain 2
EXO5 exonuclease 5
FAM86B1 family with sequence similarity 86, member B1
FBXL6 F-box and leucine-rich repeat protein 6
FKBP5 FK506 binding protein 5
FMOD fibromodulin
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAREM GRB2 associated, regulator of MAPK1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR19 G protein-coupled receptor 19
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCA2A guanylate cyclase activator 2A (guanylin)
HIST1H3G histone cluster 1, H3g
HOXB9 homeobox B9
IL2 interleukin 2
IL7 interleukin 7
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF3 Kruppel-like factor 3 (basic)
KRT8P12 keratin 8 pseudogene 12
LPAR3 lysophosphatidic acid receptor 3
LZTR1 leucine-zipper-like transcription regulator 1
MARC1 mitochondrial amidoxime reducing component 1
MIR22HG MIR22 host gene
MOGS mannosyl-oligosaccharide glucosidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NNAT neuronatin
OCLN occludin
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE8B phosphodiesterase 8B
PDZD7 PDZ domain containing 7
PLA2G1B phospholipase A2, group IB (pancreas)
POU5F1B POU class 5 homeobox 1B
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRDM12 PR domain containing 12
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRF1 perforin 1 (pore forming protein)
PRR7 proline rich 7 (synaptic)
PUS1 pseudouridylate synthase 1
REPS2 RALBP1 associated Eps domain containing 2
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TERT telomerase reverse transcriptase
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAF1 TNF receptor-associated factor 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TSC22D4 TSC22 domain family, member 4
UNC13A unc-13 homolog A (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
UPK3A uroplakin 3A
USP32 ubiquitin specific peptidase 32
VN1R1 vomeronasal 1 receptor 1
WDR25 WD repeat domain 25
ZNF696 zinc finger protein 696
ZNF76 zinc finger protein 76
ZNF81 zinc finger protein 81
ZNHIT2 zinc finger, HIT-type containing 2