mitral valve prolapse Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A mitral valve disease where one or both of the cusps of the mitral valve bulge or collapse backward in the left atrium during systole. (Human Disease Ontology, DOID_988)
Similar Terms
Downloads & Tools

Genes

107 genes co-occuring with the disease mitral valve prolapse in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FBN1 fibrillin 1 1.96567
FBN2 fibrillin 2 1.30838
WRNIP1 Werner helicase interacting protein 1 1.2582
AVL9 AVL9 homolog (S. cerevisiase) 1.24168
PDLIM1 PDZ and LIM domain 1 1.1524
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.0816
TNXB tenascin XB 1.05345
TNXA tenascin XA (pseudogene) 1.04504
B3GAT3 beta-1,3-glucuronyltransferase 3 1.01512
COL5A2 collagen, type V, alpha 2 0.991909
MGAM maltase-glucoamylase 0.947852
TBRG1 transforming growth factor beta regulator 1 0.888029
TGFBR1 transforming growth factor, beta receptor 1 0.827409
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.808129
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.783936
TNMD tenomodulin 0.783526
SH3PXD2B SH3 and PX domains 2B 0.753306
OR3A1 olfactory receptor, family 3, subfamily A, member 1 0.734622
COL11A1 collagen, type XI, alpha 1 0.733001
FLNA filamin A, alpha 0.709572
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.700321
STK25 serine/threonine kinase 25 0.679499
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.664372
PKD1P6 polycystic kidney disease 1 (autosomal dominant) pseudogene 6 0.65565
NOTCH1 notch 1 0.653671
STK3 serine/threonine kinase 3 0.644192
CNTN3 contactin 3 (plasmacytoma associated) 0.639463
COL3A1 collagen, type III, alpha 1 0.633563
IGLV5-48 immunoglobulin lambda variable 5-48 (non-functional) 0.625711
IGLV9-49 immunoglobulin lambda variable 9-49 0.611229
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.587444
STK26 serine/threonine protein kinase 26 0.576939
THRB thyroid hormone receptor, beta 0.56722
REN renin 0.543542
LAX1 lymphocyte transmembrane adaptor 1 0.541992
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.536183
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 0.534635
MDH1 malate dehydrogenase 1, NAD (soluble) 0.520731
LTBP3 latent transforming growth factor beta binding protein 3 0.520346
OPN3 opsin 3 0.518034
PGRMC1 progesterone receptor membrane component 1 0.494648
DLG3 discs, large homolog 3 (Drosophila) 0.491597
HOPX HOP homeobox 0.487027
DYNLRB1 dynein, light chain, roadblock-type 1 0.484364
LTBP2 latent transforming growth factor beta binding protein 2 0.483224
BAGE2 B melanoma antigen family, member 2 0.482464
ACE angiotensin I converting enzyme 0.480566
TSHR thyroid stimulating hormone receptor 0.469576
F10 coagulation factor X 0.464283
TRPS1 trichorhinophalangeal syndrome I 0.463149
SLK STE20-like kinase 0.458241
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.452585
VWF von Willebrand factor 0.451831
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.433397
COL2A1 collagen, type II, alpha 1 0.433397
IRF6 interferon regulatory factor 6 0.418019
DHDH dihydrodiol dehydrogenase (dimeric) 0.410909
F8 coagulation factor VIII, procoagulant component 0.401572
PF4 platelet factor 4 0.395608
BMP4 bone morphogenetic protein 4 0.391885
ROM1 retinal outer segment membrane protein 1 0.385193
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 0.378514
NPPA natriuretic peptide A 0.378514
WDR20 WD repeat domain 20 0.353027
AGTR1 angiotensin II receptor, type 1 0.351187
KIAA0101 KIAA0101 0.347511
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.342739
LATS2 large tumor suppressor kinase 2 0.325552
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.321909
GALNS galactosamine (N-acetyl)-6-sulfatase 0.313552
SMAD3 SMAD family member 3 0.304864
LOX lysyl oxidase 0.304142
TGFB2 transforming growth factor, beta 2 0.302337
PRRC2A proline-rich coiled-coil 2A 0.296931
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.288668
TGM4 transglutaminase 4 0.286519
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.279367
BANF1 barrier to autointegration factor 1 0.277584
EFS embryonal Fyn-associated substrate 0.268332
TGFB1 transforming growth factor, beta 1 0.263722
POU2F3 POU class 2 homeobox 3 0.255946
MMP25 matrix metallopeptidase 25 0.247501
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.242945
ICK intestinal cell (MAK-like) kinase 0.241546
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.240148
CHAT choline O-acetyltransferase 0.23492
NF1 neurofibromin 1 0.23492
GSR glutathione reductase 0.221108
ADORA2A adenosine A2a receptor 0.218034
ADSL adenylosuccinate lyase 0.217012
RDX radixin 0.215992
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.212945
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.211261
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.210589
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.207578
IVD isovaleryl-CoA dehydrogenase 0.199033
SDF4 stromal cell derived factor 4 0.189859
ASXL1 additional sex combs like transcriptional regulator 1 0.18621
GRB2 growth factor receptor-bound protein 2 0.183835
LY96 lymphocyte antigen 96 0.181798
NAAA N-acylethanolamine acid amidase 0.179802
NPY neuropeptide Y 0.178682
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.178126
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.177851
ELN elastin 0.163111
MMP3 matrix metallopeptidase 3 0.162908
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.159302