mitral valve disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Similar Terms
Downloads & Tools

Genes

329 genes co-occuring with the disease mitral valve disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
OPN3 opsin 3 1.96192
NPPA natriuretic peptide A 1.78804
FBN1 fibrillin 1 1.69633
WRNIP1 Werner helicase interacting protein 1 1.52468
ACE angiotensin I converting enzyme 1.49306
EFS embryonal Fyn-associated substrate 1.39433
NPPB natriuretic peptide B 1.30794
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.27955
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.23516
PDZK1IP1 PDZK1 interacting protein 1 1.23169
WDR20 WD repeat domain 20 1.17679
TNMD tenomodulin 1.05387
TNNI3 troponin I type 3 (cardiac) 1.03409
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 1.02229
VMAC vimentin-type intermediate filament associated coiled-coil protein 1.01765
CRP C-reactive protein, pentraxin-related 1.00457
LAX1 lymphocyte transmembrane adaptor 1 0.9696
FBN2 fibrillin 2 0.966244
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.950352
MSTO1 misato 1, mitochondrial distribution and morphology regulator 0.939119
PDLIM1 PDZ and LIM domain 1 0.924213
PF4 platelet factor 4 0.913492
LDHA lactate dehydrogenase A 0.902389
DUOXA1 dual oxidase maturation factor 1 0.899514
PHF12 PHD finger protein 12 0.889668
AVL9 AVL9 homolog (S. cerevisiase) 0.876966
REN renin 0.864684
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.862228
PCDH8 protocadherin 8 0.86059
CMA1 chymase 1, mast cell 0.85404
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.850354
NOTCH1 notch 1 0.845031
PEX12 peroxisomal biogenesis factor 12 0.824948
VWF von Willebrand factor 0.821257
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 0.818796
F2 coagulation factor II (thrombin) 0.815514
IGLV1-47 immunoglobulin lambda variable 1-47 0.80936
PRAC1 prostate cancer susceptibility candidate 1 0.790492
CS citrate synthase 0.778613
ADRB1 adrenoceptor beta 1 0.762678
EXTL3 exostosin-like glycosyltransferase 3 0.759416
MYRF myelin regulatory factor 0.756564
C7ORF49 chromosome 7 open reading frame 49 0.729762
ADM adrenomedullin 0.722077
HP haptoglobin 0.718443
HPR haptoglobin-related protein 0.711989
GJA5 gap junction protein, alpha 5, 40kDa 0.711183
XYLT2 xylosyltransferase II 0.708364
DNAH8 dynein, axonemal, heavy chain 8 0.706754
GALNS galactosamine (N-acetyl)-6-sulfatase 0.706351
GIN1 gypsy retrotransposon integrase 1 0.703536
TNXB tenascin XB 0.696707
TNXA tenascin XA (pseudogene) 0.688692
LECT1 leukocyte cell derived chemotaxin 1 0.682693
MVD mevalonate (diphospho) decarboxylase 0.678302
PLAT plasminogen activator, tissue 0.670732
LATS2 large tumor suppressor kinase 2 0.661197
B3GAT3 beta-1,3-glucuronyltransferase 3 0.660404
CPB1 carboxypeptidase B1 (tissue) 0.655254
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.649323
ETV3 ets variant 3 0.644981
COL5A2 collagen, type V, alpha 2 0.638676
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.638282
TNNT2 troponin T type 2 (cardiac) 0.6214
PKN2 protein kinase N2 0.619051
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 0.607323
THBD thrombomodulin 0.60147
MGAM maltase-glucoamylase 0.597571
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.58939
FLNA filamin A, alpha 0.589001
AMT aminomethyltransferase 0.586665
IDS iduronate 2-sulfatase 0.578106
SRI sorcin 0.569941
SRR serine racemase 0.567997
FUT2 fucosyltransferase 2 (secretor status included) 0.55712
DYNLRB1 dynein, light chain, roadblock-type 1 0.554015
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.547419
PIR pirin (iron-binding nuclear protein) 0.544705
DCN decorin 0.541605
TBRG1 transforming growth factor beta regulator 1 0.541217
MMP1 matrix metallopeptidase 1 0.533475
S100A5 S100 calcium binding protein A5 0.531541
PLN phospholamban 0.519961
MYSM1 Myb-like, SWIRM and MPN domains 1 0.506123
KIAA0101 KIAA0101 0.506123
MON1A MON1 secretory trafficking family member A 0.505356
ICK intestinal cell (MAK-like) kinase 0.503824
ALYREF Aly/REF export factor 0.498849
MINK1 misshapen-like kinase 1 0.497703
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.490835
IGLV2-8 immunoglobulin lambda variable 2-8 0.487788
TGFBR1 transforming growth factor, beta receptor 1 0.484364
EVC Ellis van Creveld protein 0.483604
FOXO4 forkhead box O4 0.475255
RPS2 ribosomal protein S2 0.470332
MPG N-methylpurine-DNA glycosylase 0.469954
COL2A1 collagen, type II, alpha 1 0.468063
FAT3 FAT atypical cadherin 3 0.467306
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.466928
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.46655
TBX2 T-box 2 0.463149
DCPS decapping enzyme, scavenger 0.461639
CD59 CD59 molecule, complement regulatory protein 0.460883
CTAG2 cancer/testis antigen 2 0.458241
LSR lipolysis stimulated lipoprotein receptor 0.457864
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.455224
PFKM phosphofructokinase, muscle 0.455224
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.454093
PPT1 palmitoyl-protein thioesterase 1 0.453339
TNF tumor necrosis factor 0.451454
EDN1 endothelin 1 0.451454
PRRC2A proline-rich coiled-coil 2A 0.445052
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.4443
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.443547
ALB albumin 0.440914
HLA-DOB major histocompatibility complex, class II, DO beta 0.439786
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.434899
OR3A1 olfactory receptor, family 3, subfamily A, member 1 0.43227
KMT2A lysine (K)-specific methyltransferase 2A 0.429642
DHDH dihydrodiol dehydrogenase (dimeric) 0.428891
SLN sarcolipin 0.41727
SH3PXD2B SH3 and PX domains 2B 0.416147
TPH1 tryptophan hydroxylase 1 0.411283
NAAA N-acylethanolamine acid amidase 0.410161
DSE dermatan sulfate epimerase 0.408666
STAB2 stabilin 2 0.406051
COL11A1 collagen, type XI, alpha 1 0.397471
F3 coagulation factor III (thromboplastin, tissue factor) 0.394863
MMP2 matrix metallopeptidase 2 0.392257
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.392257
GJA1 gap junction protein, alpha 1, 43kDa 0.386679
F8 coagulation factor VIII, procoagulant component 0.386308
ATF2 activating transcription factor 2 0.382223
CA5B carbonic anhydrase VB, mitochondrial 0.379626
AGTR1 angiotensin II receptor, type 1 0.377031
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.375179
PAAF1 proteasomal ATPase-associated factor 1 0.373698
COX5A cytochrome c oxidase subunit Va 0.368518
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.36741
CT45A1 cancer/testis antigen family 45, member A1 0.363347
HLA-DMA major histocompatibility complex, class II, DM alpha 0.357814
FBL fibrillarin 0.355235
YME1L1 YME1-like 1 ATPase 0.351923
PRB3 proline-rich protein BstNI subfamily 3 0.348981
CDK11A cyclin-dependent kinase 11A 0.348614
STK25 serine/threonine kinase 25 0.348246
MAP9 microtubule-associated protein 9 0.347511
APLNR apelin receptor 0.345308
EFNA5 ephrin-A5 0.343473
TGFB1 transforming growth factor, beta 1 0.340173
CKB creatine kinase, brain 0.339073
GPR182 G protein-coupled receptor 182 0.338341
IL6 interleukin 6 0.336876
TBX1 T-box 1 0.333949
FXYD1 FXYD domain containing ion transport regulator 1 0.333949
ZNF185 zinc finger protein 185 (LIM domain) 0.333218
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 0.332487
PKD1P6 polycystic kidney disease 1 (autosomal dominant) pseudogene 6 0.326281
UBAP1 ubiquitin associated protein 1 0.325916
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.325187
AMD1 adenosylmethionine decarboxylase 1 0.321181
STK3 serine/threonine kinase 3 0.315729
IGLV2-14 immunoglobulin lambda variable 2-14 0.315366
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.315366
NOTO notochord homeobox 0.31464
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.312464
CNTN3 contactin 3 (plasmacytoma associated) 0.311377
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.308842
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 0.308118
COL3A1 collagen, type III, alpha 1 0.305948
KLK15 kallikrein-related peptidase 15 0.305587
RRM2 ribonucleotide reductase M2 0.304864
MARS methionyl-tRNA synthetase 0.30342
FBLL1 fibrillarin-like 1 0.301615
ADRB2 adrenoceptor beta 2, surface 0.300894
IGLV5-48 immunoglobulin lambda variable 5-48 (non-functional) 0.298731
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.297291
ANO1 anoctamin 1, calcium activated chloride channel 0.293334
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.291898
SRSF2 serine/arginine-rich splicing factor 2 0.290821
NOVA2 neuro-oncological ventral antigen 2 0.28831
GLG1 golgi glycoprotein 1 0.286519
TTC34 tetratricopeptide repeat domain 34 0.285444
IGLV9-49 immunoglobulin lambda variable 9-49 0.285444
BIN2 bridging integrator 2 0.284728
CASQ2 calsequestrin 2 (cardiac muscle) 0.283297
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 0.282225
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.275801
TUBGCP4 tubulin, gamma complex associated protein 4 0.275089
CKM creatine kinase, muscle 0.273308
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.272597
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.271886
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.271174
SPATA5 spermatogenesis associated 5 0.270108
PEPD peptidase D 0.268687
IL31RA interleukin 31 receptor A 0.266203
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.263722
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.261952
CAPN2 calpain 2, (m/II) large subunit 0.257711
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.257358
GUSB glucuronidase, beta 0.255241
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.255241
STK26 serine/threonine protein kinase 26 0.254183
UTS2 urotensin 2 0.253831
AURKAIP1 aurora kinase A interacting protein 1 0.24996
THRB thyroid hormone receptor, beta 0.245396
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.245046
KRT84 keratin 84, type II 0.241196
LDHC lactate dehydrogenase C 0.235964
RER1 retention in endoplasmic reticulum sorting receptor 1 0.234573
CA2 carbonic anhydrase II 0.233183
ESPN espin 0.231448
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.230409
IL17C interleukin 17C 0.230409
IVD isovaleryl-CoA dehydrogenase 0.230063
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.224196
MMP9 matrix metallopeptidase 9 0.223509
TKT transketolase 0.218034
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.217693
POLB polymerase (DNA directed), beta 0.217012
BLVRA biliverdin reductase A 0.217012
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.216672
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 0.216332
TPM1 tropomyosin 1 (alpha) 0.215992
BBS2 Bardet-Biedl syndrome 2 0.215314
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.212945
ZFYVE9 zinc finger, FYVE domain containing 9 0.207245
TGFB2 transforming growth factor, beta 2 0.206248
MDH1 malate dehydrogenase 1, NAD (soluble) 0.204263
LTBP3 latent transforming growth factor beta binding protein 3 0.203933
WNT3 wingless-type MMTV integration site family, member 3 0.202946
PTK2 protein tyrosine kinase 2 0.200331
MAPT microtubule-associated protein tau 0.196779
DCT dopachrome tautomerase 0.196139
RERE arginine-glutamic acid dipeptide (RE) repeats 0.194232
TRIM25 tripartite motif containing 25 0.190786
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.189859
HBA1 hemoglobin, alpha 1 0.189244
ELN elastin 0.187113
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.18651
PGRMC1 progesterone receptor membrane component 1 0.182957
RRM1 ribonucleotide reductase M1 0.181222
DLG3 discs, large homolog 3 (Drosophila) 0.180652
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.180084
HOPX HOP homeobox 0.177301
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.175947
VCAM1 vascular cell adhesion molecule 1 0.175411
LTBP2 latent transforming growth factor beta binding protein 2 0.174617
BAGE2 B melanoma antigen family, member 2 0.174093
HBA2 hemoglobin, alpha 2 0.172799
CABIN1 calcineurin binding protein 1 0.171535
IGLV3-10 immunoglobulin lambda variable 3-10 0.170299
IL1RL1 interleukin 1 receptor-like 1 0.167224
TSHR thyroid stimulating hormone receptor 0.165874
MAPK9 mitogen-activated protein kinase 9 0.165655
F10 coagulation factor X 0.162908
TRPS1 trichorhinophalangeal syndrome I 0.162306
MMP13 matrix metallopeptidase 13 0.161331
AXL AXL receptor tyrosine kinase 0.161139
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 0.159838
SLK STE20-like kinase 0.159838
TRIM21 tripartite motif containing 21 0.159658
MB myoglobin 0.157929
RSPO1 R-spondin 1 0.157929
PLG plasminogen 0.142923
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.140112
IRF6 interferon regulatory factor 6 0.139408
BMP4 bone morphogenetic protein 4 0.138806
ROM1 retinal outer segment membrane protein 1 0.138642
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 0.138473
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.137476
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.136815
SMAD3 SMAD family member 3 0.136222
LOX lysyl oxidase 0.136196
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.135609
TGM4 transglutaminase 4 0.135524
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.135495
FBLN1 fibulin 1 0.135351
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.135233
BANF1 barrier to autointegration factor 1 0.135159
IGLL5 immunoglobulin lambda-like polypeptide 5 0.135068
RING1 ring finger protein 1 0.134977
FGB fibrinogen beta chain 0.134392
POMT2 protein-O-mannosyltransferase 2 0.134326
POU2F3 POU class 2 homeobox 3 0.134193
RCAN1 regulator of calcineurin 1 0.134093
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.134076
SCG5 secretogranin V 0.134042
TOB1 transducer of ERBB2, 1 0.134025
FAT1 FAT atypical cadherin 1 0.133939
MMP25 matrix metallopeptidase 25 0.133783
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.133677
CTF1 cardiotrophin 1 0.13348
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.133407
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.133371
NF1 neurofibromin 1 0.13313
CHAT choline O-acetyltransferase 0.13313
EVL Enah/Vasp-like 0.132901
NANP N-acetylneuraminic acid phosphatase 0.132727
GSR glutathione reductase 0.132347
ADORA2A adenosine A2a receptor 0.132162
ADSL adenylosuccinate lyase 0.132099
RDX radixin 0.132037
PHB2 prohibitin 2 0.132016
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.131846
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.131738
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.131695
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.131497
TBK1 TANK-binding kinase 1 0.13143
CLEC3B C-type lectin domain family 3, member B 0.131228
RAB27A RAB27A, member RAS oncogene family 0.130787
SDF4 stromal cell derived factor 4 0.130204
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.130054
ASXL1 additional sex combs like transcriptional regulator 1 0.129901
POMT1 protein-O-mannosyltransferase 1 0.129694
GRB2 growth factor receptor-bound protein 2 0.129694
LY96 lymphocyte antigen 96 0.12951
DAND5 DAN domain family member 5, BMP antagonist 0.12943
PHGDH phosphoglycerate dehydrogenase 0.129215
NPY neuropeptide Y 0.129215
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.12916
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.129133
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 0.128459
WEE1 WEE1 G2 checkpoint kinase 0.127342
MMP3 matrix metallopeptidase 3 0.12731
PTGDR prostaglandin D2 receptor (DP) 0.127248
TIMP4 TIMP metallopeptidase inhibitor 4 0.127185
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.126497
SIRPA signal-regulatory protein alpha 0.126464