mitosome Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria. (Gene Ontology, GO_0032047)
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29 proteins co-occuring with the mitosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
KIAA1958 KIAA1958 1.72057
MRO maestro 1.59083
QRICH1 glutamine-rich 1 1.56617
PMPCB peptidase (mitochondrial processing) beta 1.52428
ISCU iron-sulfur cluster assembly enzyme 1.48419
KCTD1 potassium channel tetramerization domain containing 1 1.44234
IL20RB interleukin 20 receptor beta 1.42711
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.39294
ZMYM4 zinc finger, MYM-type 4 1.38405
ZMYM2 zinc finger, MYM-type 2 1.26868
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 1.24602
ZMYM3 zinc finger, MYM-type 3 1.14034
FXN frataxin 1.03829
NNT nicotinamide nucleotide transhydrogenase 0.876409
HSPA4 heat shock 70kDa protein 4 0.708808
FES FES proto-oncogene, tyrosine kinase 0.702626
RNMT RNA (guanine-7-) methyltransferase 0.702626
LAP3 leucine aminopeptidase 3 0.617557
CDSN corneodesmosin 0.566754
SAMM50 SAMM50 sorting and assembly machinery component 0.515716
FDXR ferredoxin reductase 0.510011
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.483676
ADRB1 adrenoceptor beta 1 0.425531
PPA1 pyrophosphatase (inorganic) 1 0.42082
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.354042
CRYZ crystallin, zeta (quinone reductase) 0.288829
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.229888
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.21716
ACO2 aconitase 2, mitochondrial 0.177724