mitochondrial outer membrane Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. (Gene Ontology, GO_0005741)
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Genes

241 proteins co-occuring with the mitochondrial outer membrane cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 2.45115
VDAC1 voltage-dependent anion channel 1 2.39762
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 2.19185
BAX BCL2-associated X protein 2.12458
HK1 hexokinase 1 1.97203
VDAC2 voltage-dependent anion channel 2 1.82863
MAOB monoamine oxidase B 1.69216
BCL2L1 BCL2-like 1 1.68238
MFN2 mitofusin 2 1.64075
MAOA monoamine oxidase A 1.60651
VDAC3 voltage-dependent anion channel 3 1.60301
CYB5A cytochrome b5 type A (microsomal) 1.57932
CISD1 CDGSH iron sulfur domain 1 1.57645
STAR steroidogenic acute regulatory protein 1.50001
TSPO translocator protein (18kDa) 1.46156
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) 1.46156
SAMM50 SAMM50 sorting and assembly machinery component 1.4198
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast) 1.41867
MFN1 mitofusin 1 1.37133
DNM1L dynamin 1-like 1.30927
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 1.26921
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 1.26709
HK2 hexokinase 2 1.23975
DIABLO diablo, IAP-binding mitochondrial protein 1.22412
BCL2 B-cell CLL/lymphoma 2 1.20395
GDAP1 ganglioside induced differentiation associated protein 1 1.19365
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 1.17517
SYNJ2BP synaptojanin 2 binding protein 1.15876
MAVS mitochondrial antiviral signaling protein 1.11225
MFF mitochondrial fission factor 1.09136
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.08526
TOB1 transducer of ERBB2, 1 1.07917
GK glycerol kinase 1.07258
ENDOG endonuclease G 0.978074
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 0.954005
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.941162
CPT1A carnitine palmitoyltransferase 1A (liver) 0.917177
MARCH5 membrane-associated ring finger (C3HC4) 5 0.913909
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 0.885628
HTRA2 HtrA serine peptidase 2 0.880094
RHOT1 ras homolog family member T1 0.875488
PLSCR3 phospholipid scramblase 3 0.875028
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.851583
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.840564
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.83781
PPIF peptidylprolyl isomerase F 0.836433
MTX1 metaxin 1 0.818993
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 0.807524
APAF1 apoptotic peptidase activating factor 1 0.781869
SUOX sulfite oxidase 0.78004
MTX2 metaxin 2 0.778669
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.774101
MOCOS molybdenum cofactor sulfurase 0.757253
ACBD3 acyl-CoA binding domain containing 3 0.711908
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.707039
DNM1 dynamin 1 0.70439
USP30 ubiquitin specific peptidase 30 0.693393
CISD2 CDGSH iron sulfur domain 2 0.689451
MGST1 microsomal glutathione S-transferase 1 0.687701
IMMT inner membrane protein, mitochondrial 0.68639
MTCH2 mitochondrial carrier 2 0.68508
GIMAP5 GTPase, IMAP family member 5 0.66726
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.659913
DHFR dihydrofolate reductase 0.655602
CPT2 carnitine palmitoyltransferase 2 0.653019
MARC1 mitochondrial amidoxime reducing component 1 0.652159
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 0.651299
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 0.641858
TP53 tumor protein p53 0.638005
CHKB choline kinase beta 0.630318
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 0.630318
MTCH1 mitochondrial carrier 1 0.626057
CPT1C carnitine palmitoyltransferase 1C 0.625206
OPA1 optic atrophy 1 (autosomal dominant) 0.608241
PKLR pyruvate kinase, liver and RBC 0.606128
PARL presenilin associated, rhomboid-like 0.601487
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.599381
MARC2 mitochondrial amidoxime reducing component 2 0.594753
HSPA4 heat shock 70kDa protein 4 0.593912
PARK2 parkin RBR E3 ubiquitin protein ligase 0.591812
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.577999
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1 0.575495
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.571329
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 0.57008
PINK1 PTEN induced putative kinase 1 0.569664
SIAH3 siah E3 ubiquitin protein ligase family member 3 0.568832
PKM pyruvate kinase, muscle 0.567585
TOMM34 translocase of outer mitochondrial membrane 34 0.557629
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3 0.5568
ERI1 exoribonuclease 1 0.546472
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like 0.545236
CKMT1B creatine kinase, mitochondrial 1B 0.540294
NLRX1 NLR family member X1 0.535361
MLXIP MLX interacting protein 0.531258
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.52675
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.512455
GSTM2 glutathione S-transferase mu 2 (muscle) 0.512455
CYB5R3 cytochrome b5 reductase 3 0.509197
AKAP1 A kinase (PRKA) anchor protein 1 0.504318
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.49742
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.485693
MDH1 malate dehydrogenase 1, NAD (soluble) 0.480453
DNAH8 dynein, axonemal, heavy chain 8 0.479245
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.478038
MRPL47 mitochondrial ribosomal protein L47 0.47442
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.473617
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 0.461998
TEX2 testis expressed 2 0.4608
PLS3 plastin 3 0.459602
THBS3 thrombospondin 3 0.458006
RNF185 ring finger protein 185 0.457606
ARMCX3 armadillo repeat containing, X-linked 3 0.456809
SOD2 superoxide dismutase 2, mitochondrial 0.452825
C1QTNF6 C1q and tumor necrosis factor related protein 6 0.45004
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.447656
HCCS holocytochrome c synthase 0.445275
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 0.4425
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.441312
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.440124
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 0.432224
STARD4 StAR-related lipid transfer (START) domain containing 4 0.429859
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.428678
BID BH3 interacting domain death agonist 0.428284
NEU4 sialidase 4 0.412601
SFXN1 sideroflexin 1 0.409089
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 0.405582
PRUNE2 prune homolog 2 (Drosophila) 0.40247
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 0.397811
POMC proopiomelanocortin 0.386208
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 0.380045
GHITM growth hormone inducible transmembrane protein 0.373132
OAT ornithine aminotransferase 0.371216
IRF3 interferon regulatory factor 3 0.368919
GFER growth factor, augmenter of liver regeneration 0.367388
CKMT1A creatine kinase, mitochondrial 1A 0.365095
SLC7A14 solute carrier family 7, member 14 0.362422
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 0.361277
RAB6B RAB6B, member RAS oncogene family 0.360133
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.360133
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.354802
PDZD8 PDZ domain containing 8 0.352142
STARD7 StAR-related lipid transfer (START) domain containing 7 0.351382
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 0.351382
ATAD3A ATPase family, AAA domain containing 3A 0.346071
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.345314
BAD BCL2-associated agonist of cell death 0.344178
TRAK1 trafficking protein, kinesin binding 1 0.341151
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.329461
FUNDC1 FUN14 domain containing 1 0.328708
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.327581
TAZ tafazzin 0.325702
FAM162A family with sequence similarity 162, member A 0.323075
BCL2A1 BCL2-related protein A1 0.31783
SCCPDH saccharopine dehydrogenase (putative) 0.313718
FGD4 FYVE, RhoGEF and PH domain containing 4 0.309986
KRAS Kirsten rat sarcoma viral oncogene homolog 0.309613
QTRT1 queuine tRNA-ribosyltransferase 1 0.303655
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.302912
CKB creatine kinase, brain 0.291787
PISD phosphatidylserine decarboxylase 0.291787
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.285876
ASPG asparaginase 0.283295
FKBP8 FK506 binding protein 8, 38kDa 0.282926
PLA2G1B phospholipase A2, group IB (pancreas) 0.278141
MGARP mitochondria-localized glutamic acid-rich protein 0.276671
VCP valosin containing protein 0.276671
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 0.275569
GLRX2 glutaredoxin 2 0.274835
DMPK dystrophia myotonica-protein kinase 0.268603
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.265311
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 0.259473
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.252564
BAK1 BCL2-antagonist/killer 1 0.251839
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.250751
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 0.242797
CDSN corneodesmosin 0.242797
ESYT2 extended synaptotagmin-like protein 2 0.240996
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 0.240636
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.239197
HSPA8 heat shock 70kDa protein 8 0.23776
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.235249
GRK4 G protein-coupled receptor kinase 4 0.233459
STARD6 StAR-related lipid transfer (START) domain containing 6 0.233459
TCTEX1D4 Tctex1 domain containing 4 0.233459
PCTP phosphatidylcholine transfer protein 0.231315
APOE apolipoprotein E 0.230958
DENR density-regulated protein 0.229176
BRWD1 bromodomain and WD repeat domain containing 1 0.224558
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.22279
CYB5R2 cytochrome b5 reductase 2 0.222083
MX2 MX dynamin-like GTPase 2 0.220673
MB myoglobin 0.219617
ILF2 interleukin enhancer binding factor 2 0.218563
ACOT12 acyl-CoA thioesterase 12 0.21681
ATCAY ataxia, cerebellar, Cayman type 0.21646
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.216111
RMDN3 regulator of microtubule dynamics 3 0.213669
CYB5R1 cytochrome b5 reductase 1 0.207794
PPIC peptidylprolyl isomerase C (cyclophilin C) 0.200328
HSPA1L heat shock 70kDa protein 1-like 0.198991
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.196999
ANXA5 annexin A5 0.194371
AK2 adenylate kinase 2 0.19307
WSB1 WD repeat and SOCS box containing 1 0.192746
ALB albumin 0.189539
SEPT4 septin 4 0.187333
INS insulin 0.187333
GCK glucokinase (hexokinase 4) 0.186708
LRRK2 leucine-rich repeat kinase 2 0.186397
NT5E 5'-nucleotidase, ecto (CD73) 0.18516
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.184853
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.183025
RNF43 ring finger protein 43 0.182122
NGF nerve growth factor (beta polypeptide) 0.179167
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 0.179167
OTC ornithine carbamoyltransferase 0.178877
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 0.177439
FAM83H family with sequence similarity 83, member H 0.175745
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.175466
FOSL2 FOS-like antigen 2 0.173273
BECN1 beclin 1, autophagy related 0.172468
STARD3 StAR-related lipid transfer (START) domain containing 3 0.171149
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.168349
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.167125
PARP1 poly (ADP-ribose) polymerase 1 0.165463
GPX5 glutathione peroxidase 5 0.165
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.16477
CKM creatine kinase, muscle 0.16298
GPX4 glutathione peroxidase 4 0.161905
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.160863
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.160658
BPIFA1 BPI fold containing family A, member 1 0.160658
NUAK2 NUAK family, SNF1-like kinase, 2 0.160456
RALBP1 ralA binding protein 1 0.159074
MRPS12 mitochondrial ribosomal protein S12 0.158882
SYNJ2 synaptojanin 2 0.158692
LIAS lipoic acid synthetase 0.158315
KPTN kaptin (actin binding protein) 0.158129
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.157578
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 0.157218
GPX1 glutathione peroxidase 1 0.156513