microfibril Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins. (Gene Ontology, GO_0001527)
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Genes

154 proteins co-occuring with the microfibril cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
FBN1 fibrillin 1 4.33684
MFAP2 microfibrillar-associated protein 2 2.9705
FBN2 fibrillin 2 2.9494
ELN elastin 2.4717
LTBP2 latent transforming growth factor beta binding protein 2 2.27286
LTBP3 latent transforming growth factor beta binding protein 3 2.18227
LTBP1 latent transforming growth factor beta binding protein 1 2.16906
MFAP5 microfibrillar associated protein 5 2.12822
EMILIN1 elastin microfibril interfacer 1 2.05394
FBLN5 fibulin 5 1.87313
FBN3 fibrillin 3 1.86624
LTBP4 latent transforming growth factor beta binding protein 4 1.65332
EMILIN2 elastin microfibril interfacer 2 1.53896
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.4938
FBLN2 fibulin 2 1.47061
MFAP4 microfibrillar-associated protein 4 1.3363
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 1.32167
FN1 fibronectin 1 1.2921
LOXL1 lysyl oxidase-like 1 1.23713
TGFB1 transforming growth factor, beta 1 1.23661
LOX lysyl oxidase 1.19417
ADAMTSL4 ADAMTS-like 4 1.1685
FBLN1 fibulin 1 1.16081
ADAMTSL2 ADAMTS-like 2 1.14904
TNC tenascin C 1.11021
VCAN versican 1.07613
MFAP1 microfibrillar-associated protein 1 1.05589
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 1.04884
DCN decorin 1.03779
COL6A1 collagen, type VI, alpha 1 1.02879
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.933601
ADAMTSL5 ADAMTS-like 5 0.883782
C2CD4B C2 calcium-dependent domain containing 4B 0.883782
COL6A2 collagen, type VI, alpha 2 0.833679
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 0.8089
GRHL1 grainyhead-like 1 (Drosophila) 0.802479
MMRN1 multimerin 1 0.788733
BMP10 bone morphogenetic protein 10 0.782784
MFAP3 microfibrillar-associated protein 3 0.782326
COL6A3 collagen, type VI, alpha 3 0.770451
KHK ketohexokinase (fructokinase) 0.756799
COL6A6 collagen, type VI, alpha 6 0.75317
SEBOX SEBOX homeobox 0.727494
VWF von Willebrand factor 0.707482
TBRG1 transforming growth factor beta regulator 1 0.698223
BGN biglycan 0.668992
APCS amyloid P component, serum 0.660776
FURIN furin (paired basic amino acid cleaving enzyme) 0.61968
THOP1 thimet oligopeptidase 1 0.607818
TWSG1 twisted gastrulation BMP signaling modulator 1 0.560943
RARA retinoic acid receptor, alpha 0.555145
IFI44L interferon-induced protein 44-like 0.541117
SCUBE1 signal peptide, CUB domain, EGF-like 1 0.539883
LAMA1 laminin, alpha 1 0.531668
MMP2 matrix metallopeptidase 2 0.517348
AKAP2 A kinase (PRKA) anchor protein 2 0.507977
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.497015
SDC2 syndecan 2 0.494585
MMP1 matrix metallopeptidase 1 0.490539
RIN2 Ras and Rab interactor 2 0.481258
BMP5 bone morphogenetic protein 5 0.477233
PROK1 prokineticin 1 0.476831
STK10 serine/threonine kinase 10 0.462398
COL3A1 collagen, type III, alpha 1 0.459602
CNTNAP2 contactin associated protein-like 2 0.459602
PAPLN papilin, proteoglycan-like sulfated glycoprotein 0.458803
TSKU tsukushi, small leucine rich proteoglycan 0.452029
ANGPTL1 angiopoietin-like 1 0.435775
BMP7 bone morphogenetic protein 7 0.431829
NID1 nidogen 1 0.430253
STRBP spermatid perinuclear RNA binding protein 0.429859
ADGRE5 adhesion G protein-coupled receptor E5 0.429072
CD44 CD44 molecule (Indian blood group) 0.426711
MMP9 matrix metallopeptidase 9 0.41143
CILP2 cartilage intermediate layer protein 2 0.406361
TNXA tenascin XA (pseudogene) 0.390068
TNXB tenascin XB 0.389682
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 0.386208
COL14A1 collagen, type XIV, alpha 1 0.377354
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.372749
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.365477
COL1A2 collagen, type I, alpha 2 0.361659
SLC44A2 solute carrier family 44 (choline transporter), member 2 0.354042
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.351002
PDPN podoplanin 0.347967
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.341151
TTR transthyretin 0.339261
TGFBR1 transforming growth factor, beta receptor 1 0.332848
LOXL3 lysyl oxidase-like 3 0.327956
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.327205
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.325702
MMP3 matrix metallopeptidase 3 0.325327
ZBTB14 zinc finger and BTB domain containing 14 0.320077
MATN1 matrilin 1, cartilage matrix protein 0.319702
NRP2 neuropilin 2 0.317456
TNRC6A trinucleotide repeat containing 6A 0.311851
SOX18 SRY (sex determining region Y)-box 18 0.305888
COL7A1 collagen, type VII, alpha 1 0.293637
SNRPN small nuclear ribonucleoprotein polypeptide N 0.284401
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.276671
FAXDC2 fatty acid hydroxylase domain containing 2 0.275202
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.266042
BCAN brevican 0.266042
BMP4 bone morphogenetic protein 4 0.26312
NCALD neurocalcin delta 0.252564
LAX1 lymphocyte transmembrane adaptor 1 0.250751
UGP2 UDP-glucose pyrophosphorylase 2 0.244962
FBLL1 fibrillarin-like 1 0.244601
GREM1 gremlin 1, DAN family BMP antagonist 0.243158
FBL fibrillarin 0.241716
F9 coagulation factor IX 0.241356
DAND5 DAN domain family member 5, BMP antagonist 0.239197
FGA fibrinogen alpha chain 0.237042
TGFBI transforming growth factor, beta-induced, 68kDa 0.228819
MSTN myostatin 0.228464
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 0.228108
MATN2 matrilin 2 0.22173
CD79A CD79a molecule, immunoglobulin-associated alpha 0.218563
YBX1 Y box binding protein 1 0.217511
SMAD3 SMAD family member 3 0.21716
GDF11 growth differentiation factor 11 0.211587
LATS1 large tumor suppressor kinase 1 0.208481
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 0.204039
TAGLN transgelin 0.200663
IVL involucrin 0.197993
RAB31 RAB31, member RAS oncogene family 0.197662
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.196669
B3GAT1 beta-1,3-glucuronyltransferase 1 0.192746
CA8 carbonic anhydrase VIII 0.190814
ITGB4 integrin, beta 4 0.187646
LYZ lysozyme 0.186397
CHAD chondroadherin 0.184853
MMP25 matrix metallopeptidase 25 0.180045
MMP13 matrix metallopeptidase 13 0.175188
PEG10 paternally expressed 10 0.174635
CRYGD crystallin, gamma D 0.173814
CHIA chitinase, acidic 0.170114
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.168349
TCHH trichohyalin 0.168349
IVD isovaleryl-CoA dehydrogenase 0.168101
ATRN attractin 0.167366
PKD1P6 polycystic kidney disease 1 (autosomal dominant) pseudogene 6 0.166884
SPP1 secreted phosphoprotein 1 0.163865
SHF Src homology 2 domain containing F 0.162763
THBS1 thrombospondin 1 0.16233
NOTCH1 notch 1 0.162117
FTL ferritin, light polypeptide 0.161905
FNDC3A fibronectin type III domain containing 3A 0.161693
MMP12 matrix metallopeptidase 12 0.161068
FTH1 ferritin, heavy polypeptide 1 0.160863
CNGA3 cyclic nucleotide gated channel alpha 3 0.160254
DLX1 distal-less homeobox 1 0.158315
HLA-DOB major histocompatibility complex, class II, DO beta 0.158315
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.156688