methylbenzethonium chloride-3943 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the methylbenzethonium chloride-3943 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ADD2 adducin 2 (beta)
ALX4 ALX homeobox 4
AMOT angiomotin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATXN3 ataxin 3
BDKRB2 bradykinin receptor B2
BMP1 bone morphogenetic protein 1
BTN3A1 butyrophilin, subfamily 3, member A1
C1ORF95 chromosome 1 open reading frame 95
CA9 carbonic anhydrase IX
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD48 CD48 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEP112 centrosomal protein 112kDa
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLDN17 claudin 17
COL1A1 collagen, type I, alpha 1
CTIF CBP80/20-dependent translation initiation factor
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DIO2 deiodinase, iodothyronine, type II
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FGF4 fibroblast growth factor 4
FOS FBJ murine osteosarcoma viral oncogene homolog
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GP1BB glycoprotein Ib (platelet), beta polypeptide
GRM7 glutamate receptor, metabotropic 7
HHLA1 HERV-H LTR-associating 1
HOXA10 homeobox A10
HR hair growth associated
ICAM1 intercellular adhesion molecule 1
IL1RN interleukin 1 receptor antagonist
IL21R interleukin 21 receptor
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
ITGA7 integrin, alpha 7
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KEL Kell blood group, metallo-endopeptidase
KIAA1467 KIAA1467
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
KRT32 keratin 32, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA3 melanoma antigen family A3
MAGEA5 melanoma antigen family A5
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
N4BP2L1 NEDD4 binding protein 2-like 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEUROD6 neuronal differentiation 6
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUPR1 nuclear protein, transcriptional regulator, 1
PDIA2 protein disulfide isomerase family A, member 2
PER1 period circadian clock 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIDD1 p53-induced death domain protein 1
PPARD peroxisome proliferator-activated receptor delta
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PRR34 proline rich 34
PSAT1 phosphoserine aminotransferase 1
RGS14 regulator of G-protein signaling 14
RIMS3 regulating synaptic membrane exocytosis 3
RORC RAR-related orphan receptor C
RPL35A ribosomal protein L35a
RUNX1 runt-related transcription factor 1
SAFB scaffold attachment factor B
SAYSD1 SAYSVFN motif domain containing 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SPN sialophorin
TAT tyrosine aminotransferase
TGM2 transglutaminase 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNK2 tyrosine kinase, non-receptor, 2
TNXB tenascin XB
TSC22D3 TSC22 domain family, member 3
VLDLR very low density lipoprotein receptor
ZNF280A zinc finger protein 280A

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC6 armadillo repeat containing 6
ASAP1-IT1 ASAP1 intronic transcript 1
ATF7IP2 activating transcription factor 7 interacting protein 2
BAHCC1 BAH domain and coiled-coil containing 1
BBS10 Bardet-Biedl syndrome 10
C17ORF53 chromosome 17 open reading frame 53
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF44 chromosome 2 open reading frame 44
CAMTA1 calmodulin binding transcription activator 1
CASKIN2 CASK interacting protein 2
CCDC132 coiled-coil domain containing 132
CCNE2 cyclin E2
CD34 CD34 molecule
CD3EAP CD3e molecule, epsilon associated protein
CD82 CD82 molecule
CDHR2 cadherin-related family member 2
DBR1 debranching RNA lariats 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAAF2 dynein, axonemal, assembly factor 2
DTX2 deltex 2, E3 ubiquitin ligase
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ETNK2 ethanolamine kinase 2
F8 coagulation factor VIII, procoagulant component
FAM50B family with sequence similarity 50, member B
FOXC1 forkhead box C1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GK3P glycerol kinase 3 pseudogene
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR27 G protein-coupled receptor 27
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRWD1 glutamate-rich WD repeat containing 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AJ histone cluster 1, H2aj
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IP6K1 inositol hexakisphosphate kinase 1
IQSEC2 IQ motif and Sec7 domain 2
ITGA8 integrin, alpha 8
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
KLHL21 kelch-like family member 21
KRI1 KRI1 homolog (S. cerevisiae)
KRT83 keratin 83, type II
MANSC1 MANSC domain containing 1
MCM10 minichromosome maintenance complex component 10
METTL16 methyltransferase like 16
METTL8 methyltransferase like 8
MRPL44 mitochondrial ribosomal protein L44
MTA2 metastasis associated 1 family, member 2
NPY1R neuropeptide Y receptor Y1
NRSN2 neurensin 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCDHB3 protocadherin beta 3
PDE12 phosphodiesterase 12
PHC1 polyhomeotic homolog 1 (Drosophila)
PLAC4 placenta-specific 4
PODNL1 podocan-like 1
POMT2 protein-O-mannosyltransferase 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRR4 proline rich 4 (lacrimal)
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PSG4 pregnancy specific beta-1-glycoprotein 4
RAB40C RAB40C, member RAS oncogene family
RBM41 RNA binding motif protein 41
RFXAP regulatory factor X-associated protein
RNF126P1 ring finger protein 126 pseudogene 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCGB2A2 secretoglobin, family 2A, member 2
SENP7 SUMO1/sentrin specific peptidase 7
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLIT2 slit homolog 2 (Drosophila)
SPINK4 serine peptidase inhibitor, Kazal type 4
TAOK1 TAO kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM180 transmembrane protein 180
TMSB15A thymosin beta 15a
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM21 tripartite motif containing 21
UPK2 uroplakin 2
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
XK X-linked Kx blood group
ZBTB48 zinc finger and BTB domain containing 48
ZBTB6 zinc finger and BTB domain containing 6
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF446 zinc finger protein 446
ZNF668 zinc finger protein 668
ZNF862 zinc finger protein 862
ZSWIM1 zinc finger, SWIM-type containing 1