mestranol-3346 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


196 genes differentially expressed following the mestranol-3346 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACTC1 actin, alpha, cardiac muscle 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AHNAK2 AHNAK nucleoprotein 2
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARPIN actin-related protein 2/3 complex inhibitor
ATF3 activating transcription factor 3
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BDKRB2 bradykinin receptor B2
BIRC3 baculoviral IAP repeat containing 3
BTF3P11 basic transcription factor 3 pseudogene 11
CALB1 calbindin 1, 28kDa
CDK6 cyclin-dependent kinase 6
CEMIP cell migration inducing protein, hyaluronan binding
CERS4 ceramide synthase 4
CLCA1 chloride channel accessory 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL3A1 collagen, type III, alpha 1
CRYAA crystallin, alpha A
CTNS cystinosin, lysosomal cystine transporter
CTSZ cathepsin Z
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
DEF6 differentially expressed in FDCP 6 homolog (mouse)
EGR3 early growth response 3
EPHB2 EPH receptor B2
EPYC epiphycan
ERCC2 excision repair cross-complementation group 2
FCMR Fc fragment of IgM receptor
FKRP fukutin related protein
FSCN3 fascin actin-bundling protein 3, testicular
GAB1 GRB2-associated binding protein 1
GLDC glycine dehydrogenase (decarboxylating)
GLS glutaminase
GM2A GM2 ganglioside activator
HDLBP high density lipoprotein binding protein
HIPK2 homeodomain interacting protein kinase 2
HMOX1 heme oxygenase 1
ICA1 islet cell autoantigen 1, 69kDa
IL6R interleukin 6 receptor
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JUN jun proto-oncogene
KANSL3 KAT8 regulatory NSL complex subunit 3
KIDINS220 kinase D-interacting substrate, 220kDa
KLF13 Kruppel-like factor 13
LAMP1 lysosomal-associated membrane protein 1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LRP4 low density lipoprotein receptor-related protein 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPT microtubule-associated protein tau
MARK2 MAP/microtubule affinity-regulating kinase 2
MBNL2 muscleblind-like splicing regulator 2
MED16 mediator complex subunit 16
MLXIP MLX interacting protein
MX1 MX dynamin-like GTPase 1
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MZF1 myeloid zinc finger 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NCOR2 nuclear receptor corepressor 2
NF2 neurofibromin 2 (merlin)
NOTCH4 notch 4
NPTXR neuronal pentraxin receptor
NR2F1 nuclear receptor subfamily 2, group F, member 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAUR plasminogen activator, urokinase receptor
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PODNL1 podocan-like 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PVR poliovirus receptor
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUSC2 RUN and SH3 domain containing 2
SDS serine dehydratase
SEC14L2 SEC14-like 2 (S. cerevisiae)
SH2D2A SH2 domain containing 2A
SH2D3A SH2 domain containing 3A
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SORT1 sortilin 1
SPTBN5 spectrin, beta, non-erythrocytic 5
SRCAP Snf2-related CREBBP activator protein
STAB2 stabilin 2
STARD8 StAR-related lipid transfer (START) domain containing 8
STC1 stanniocalcin 1
STYK1 serine/threonine/tyrosine kinase 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAZ tafazzin
TBL1Y transducin (beta)-like 1, Y-linked
TGM2 transglutaminase 2
TMOD1 tropomodulin 1
TREX1 three prime repair exonuclease 1
TUBA3C tubulin, alpha 3c
ZC3H7B zinc finger CCCH-type containing 7B
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTN4 actinin, alpha 4
ADAP2 ArfGAP with dual PH domains 2
AGO1 argonaute RISC catalytic component 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APLP1 amyloid beta (A4) precursor-like protein 1
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C11ORF80 chromosome 11 open reading frame 80
C11ORF95 chromosome 11 open reading frame 95
C3 complement component 3
C9ORF9 chromosome 9 open reading frame 9
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC25 coiled-coil domain containing 25
CCDC69 coiled-coil domain containing 69
CD83 CD83 molecule
CDK18 cyclin-dependent kinase 18
CEP131 centrosomal protein 131kDa
CERK ceramide kinase
CFD complement factor D (adipsin)
CLIP4 CAP-GLY domain containing linker protein family, member 4
CRY2 cryptochrome circadian clock 2
CTRL chymotrypsin-like
CUL9 cullin 9
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGAT1 diacylglycerol O-acyltransferase 1
DIXDC1 DIX domain containing 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ECH1 enoyl CoA hydratase 1, peroxisomal
EFCAB2 EF-hand calcium binding domain 2
EFNA1 ephrin-A1
ERCC3 excision repair cross-complementation group 3
EXOC6B exocyst complex component 6B
FAM184A family with sequence similarity 184, member A
FAM186A family with sequence similarity 186, member A
FAM46C family with sequence similarity 46, member C
FBXO46 F-box protein 46
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH2L G patch domain containing 2-like
HDAC7 histone deacetylase 7
HOXC5 homeobox C5
HPN hepsin
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
JMJD4 jumonji domain containing 4
KCTD7 potassium channel tetramerization domain containing 7
KIAA0319L KIAA0319-like
LRRC37A3 leucine rich repeat containing 37, member A3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MTCH2 mitochondrial carrier 2
MTMR6 myotubularin related protein 6
MVP major vault protein
MXD3 MAX dimerization protein 3
MYOZ3 myozenin 3
NCALD neurocalcin delta
NPFFR1 neuropeptide FF receptor 1
PGBD5 piggyBac transposable element derived 5
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G3 phospholipase A2, group III
POTEKP POTE ankyrin domain family, member K, pseudogene
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRODH proline dehydrogenase (oxidase) 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIN2 Ras and Rab interactor 2
RNF208 ring finger protein 208
S100A9 S100 calcium binding protein A9
SETD1B SET domain containing 1B
SH2D4A SH2 domain containing 4A
SH3GL1 SH3-domain GRB2-like 1
SLC12A8 solute carrier family 12, member 8
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC22A18 solute carrier family 22, member 18
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SNRPF small nuclear ribonucleoprotein polypeptide F
SPINK5 serine peptidase inhibitor, Kazal type 5
SREBF1 sterol regulatory element binding transcription factor 1
STON1 stonin 1
SUSD6 sushi domain containing 6
TBC1D2 TBC1 domain family, member 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THRB thyroid hormone receptor, beta
TIMP2 TIMP metallopeptidase inhibitor 2
TNRC6B trinucleotide repeat containing 6B
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TTLL1 tubulin tyrosine ligase-like family member 1
UBL4A ubiquitin-like 4A
XDH xanthine dehydrogenase
ZBTB48 zinc finger and BTB domain containing 48
ZNF10 zinc finger protein 10
ZNF211 zinc finger protein 211