mental depression Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

118 genes co-occuring with the disease mental depression in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TRH thyrotropin-releasing hormone 2.0001
MAOA monoamine oxidase A 1.55336
POMC proopiomelanocortin 1.46715
CRH corticotropin releasing hormone 1.37207
DISC1 disrupted in schizophrenia 1 1.36771
PI4K2B phosphatidylinositol 4-kinase type 2 beta 1.21348
PRL prolactin 1.1072
ZNF80 zinc finger protein 80 1.08999
RNF123 ring finger protein 123 0.978426
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 0.94577
ALG9 ALG9, alpha-1,2-mannosyltransferase 0.932898
PDCD2 programmed cell death 2 0.805257
PDE4B phosphodiesterase 4B, cAMP-specific 0.761047
CDK14 cyclin-dependent kinase 14 0.757378
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 0.745985
TSNAX translin-associated factor X 0.740299
COMT catechol-O-methyltransferase 0.731381
CHRM2 cholinergic receptor, muscarinic 2 0.730976
CORT cortistatin 0.716828
EGOT eosinophil granule ontogeny transcript (non-protein coding) 0.716425
AVPR1B arginine vasopressin receptor 1B 0.697109
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.695103
FLNA filamin A, alpha 0.661594
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.661197
BDNF brain-derived neurotrophic factor 0.643797
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.626888
TOR1A torsin family 1, member A (torsin A) 0.618268
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 0.618268
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.609666
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.604981
CRHBP corticotropin releasing hormone binding protein 0.60108
IDO1 indoleamine 2,3-dioxygenase 1 0.579661
AHRR aryl-hydrocarbon receptor repressor 0.569941
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.562558
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.560227
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.541992
GHRH growth hormone releasing hormone 0.533861
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.509192
BPI bactericidal/permeability-increasing protein 0.496557
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.493503
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.491215
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.455978
NDEL1 nudE neurodevelopment protein 1-like 1 0.452962
MAOB monoamine oxidase B 0.428891
TES testin LIM domain protein 0.423265
IFI30 interferon, gamma-inducible protein 30 0.415024
GH1 growth hormone 1 0.39598
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.378514
PEG10 paternally expressed 10 0.374068
NKX2-2 NK2 homeobox 2 0.370737
SGSH N-sulfoglucosamine sulfohydrolase 0.370368
SYNE1 spectrin repeat containing, nuclear envelope 1 0.358551
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.348614
INS insulin 0.347879
ENDOG endonuclease G 0.34384
CCK cholecystokinin 0.33944
PCSK7 proprotein convertase subtilisin/kexin type 7 0.337242
CLOCK clock circadian regulator 0.331025
LCT lactase 0.323365
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.320454
HP haptoglobin 0.309566
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.307033
ALAS1 5'-aminolevulinate synthase 1 0.304864
HPR haptoglobin-related protein 0.303781
MGP matrix Gla protein 0.298731
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.298371
DNAH8 dynein, axonemal, heavy chain 8 0.290821
DCTN1 dynactin 1 0.290462
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.282582
DTNBP1 dystrobrevin binding protein 1 0.278654
ACHE acetylcholinesterase (Yt blood group) 0.271886
HNMT histamine N-methyltransferase 0.258417
EPGN epithelial mitogen 0.253831
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.248203
IL6 interleukin 6 0.237009
NPS neuropeptide S 0.234225
EP300 E1A binding protein p300 0.228333
TP73 tumor protein p73 0.22454
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.221793
EFS embryonal Fyn-associated substrate 0.211261
TF transferrin 0.20658
PHYH phytanoyl-CoA 2-hydroxylase 0.202618
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.18621
PRSS21 protease, serine, 21 (testisin) 0.183835
SP6 Sp6 transcription factor 0.180937
GAST gastrin 0.177301
TKT transketolase 0.176485
LAX1 lymphocyte transmembrane adaptor 1 0.170789
DRD4 dopamine receptor D4 0.165655
HAND1 heart and neural crest derivatives expressed 1 0.162707
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.162707
NPY neuropeptide Y 0.160761
POLG polymerase (DNA directed), gamma 0.14838
MGAM maltase-glucoamylase 0.143386
DRD3 dopamine receptor D3 0.1433
SOX10 SRY (sex determining region Y)-box 10 0.143252
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.142942
CCL11 chemokine (C-C motif) ligand 11 0.14216
TPH1 tryptophan hydroxylase 1 0.14208
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.135242
NRG1 neuregulin 1 0.134816
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.134143
FOXP2 forkhead box P2 0.134062
FGD1 FYVE, RhoGEF and PH domain containing 1 0.132137
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.131712
PMEL premelanosome protein 0.130712
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.12927
CCL5 chemokine (C-C motif) ligand 5 0.128624
PRRC2A proline-rich coiled-coil 2A 0.127579
NOS2 nitric oxide synthase 2, inducible 0.125586
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.125557
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.123484
HK1 hexokinase 1 0.122855
CREBBP CREB binding protein 0.122029
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.120715
DCXR dicarbonyl/L-xylulose reductase 0.119905
NTF3 neurotrophin 3 0.119145
DRD2 dopamine receptor D2 0.118611