membrane raft Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. (Gene Ontology, GO_0045121)
Similar Terms
Downloads & Tools

Genes

203 proteins localized to the membrane raft cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
LCK LCK proto-oncogene, Src family tyrosine kinase 0.663342
EGFR epidermal growth factor receptor 0.663342
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.663342
SULF1 sulfatase 1 0.663342
PRKCDBP protein kinase C, delta binding protein 0.663342
PLSCR1 phospholipid scramblase 1 0.663342
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.663342
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.663342
ARID3C AT rich interactive domain 3C (BRIGHT-like) 0.663342
PTRF polymerase I and transcript release factor 0.663342
PTGIS prostaglandin I2 (prostacyclin) synthase 0.663342
ANGPT1 angiopoietin 1 0.663342
LIPE lipase, hormone-sensitive 0.663342
PARK7 parkinson protein 7 0.663342
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.663342
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.663342
GHSR growth hormone secretagogue receptor 0.663342
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.663342
SDPR serum deprivation response 0.663342
CAV2 caveolin 2 0.663342
CLN3 ceroid-lipofuscinosis, neuronal 3 0.663342
THY1 Thy-1 cell surface antigen 0.663342
FLOT1 flotillin 1 0.663342
KIF18A kinesin family member 18A 0.663342
MYO1C myosin IC 0.663342
STOML2 stomatin (EPB72)-like 2 0.663342
NOS3 nitric oxide synthase 3 (endothelial cell) 0.663342
FLOT2 flotillin 2 0.663342
CARD11 caspase recruitment domain family, member 11 0.663342
NTSR1 neurotensin receptor 1 (high affinity) 0.663342
SNAP25 synaptosomal-associated protein, 25kDa 0.663342
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.663342
SCARB1 scavenger receptor class B, member 1 0.663342
HYAL2 hyaluronoglucosaminidase 2 0.663342
CAV1 caveolin 1, caveolae protein, 22kDa 0.663342
EHD2 EH-domain containing 2 0.663342
MAL mal, T-cell differentiation protein 0.663342
CLIP3 CAP-GLY domain containing linker protein 3 0.663342
CXADR coxsackie virus and adenovirus receptor 0.663342
DPP4 dipeptidyl-peptidase 4 0.663342
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.663342
STOM stomatin 0.663342
LYN LYN proto-oncogene, Src family tyrosine kinase 0.663342
CD24 CD24 molecule 0.663342
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 0.663342
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 0.663342
FAIM2 Fas apoptotic inhibitory molecule 2 0.663342
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.663342
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.663342
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.663342
PPT1 palmitoyl-protein thioesterase 1 0.663342
KDR kinase insert domain receptor 0.663342
DLC1 DLC1 Rho GTPase activating protein 0.663342
MAPK3 mitogen-activated protein kinase 3 0.663342
CD48 CD48 molecule 0.663342
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.663342
MAPK1 mitogen-activated protein kinase 1 0.663342
TEK TEK tyrosine kinase, endothelial 0.663342
S1PR1 sphingosine-1-phosphate receptor 1 0.663342
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 0.663342
HCK HCK proto-oncogene, Src family tyrosine kinase 0.663342
TDGF1 teratocarcinoma-derived growth factor 1 0.663342
FAS Fas cell surface death receptor 0.663342
SHH sonic hedgehog 0.237908
CD226 CD226 molecule 0.237908
RANGRF RAN guanine nucleotide release factor 0.237908
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.237908
PLVAP plasmalemma vesicle associated protein 0.237908
STX12 syntaxin 12 0.237908
SELE selectin E 0.237908
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.237908
LAT linker for activation of T cells 0.237908
CAPN2 calpain 2, (m/II) large subunit 0.237908
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.237908
GPM6B glycoprotein M6B 0.237908
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.237908
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.237908
CD79A CD79a molecule, immunoglobulin-associated alpha 0.237908
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.237908
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.237908
MALL mal, T-cell differentiation protein-like 0.237908
MYOF myoferlin 0.237908
FURIN furin (paired basic amino acid cleaving enzyme) 0.237908
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.237908
BTK Bruton agammaglobulinemia tyrosine kinase 0.237908
ACE2 angiotensin I converting enzyme 2 0.237908
RAP2B RAP2B, member of RAS oncogene family 0.237908
SCN5A sodium channel, voltage gated, type V alpha subunit 0.237908
RFTN1 raftlin, lipid raft linker 1 0.237908
IRS1 insulin receptor substrate 1 0.237908
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.237908
PSEN1 presenilin 1 0.237908
ITLN1 intelectin 1 (galactofuranose binding) 0.237908
F2R coagulation factor II (thrombin) receptor 0.237908
TNF tumor necrosis factor 0.237908
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.237908
APP amyloid beta (A4) precursor protein 0.237908
LAT2 linker for activation of T cells family, member 2 0.237908
DMD dystrophin 0.237908
INSR insulin receptor 0.237908
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.237908
PRNP prion protein 0.237908
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.237908
CDH13 cadherin 13 0.237908
GPC1 glypican 1 0.237908
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.237908
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.237908
SORBS1 sorbin and SH3 domain containing 1 0.237908
HDAC6 histone deacetylase 6 0.237908
MYADM myeloid-associated differentiation marker 0.237908
PTCH1 patched 1 0.237908
ADAM17 ADAM metallopeptidase domain 17 0.237908
CAV3 caveolin 3 0.098109
CRB2 crumbs family member 2 0.098109
ADCY2 adenylate cyclase 2 (brain) 0.098109
JAK2 Janus kinase 2 0.098109
PSEN2 presenilin 2 0.098109
GJA1 gap junction protein, alpha 1, 43kDa 0.098109
ANXA13 annexin A13 0.098109
AKAP6 A kinase (PRKA) anchor protein 6 0.098109
NOS1 nitric oxide synthase 1 (neuronal) 0.098109
RAB5A RAB5A, member RAS oncogene family 0.03318
LRRK2 leucine-rich repeat kinase 2 0.03318
PLLP plasmolipin 0.03318
GRIP1 glutamate receptor interacting protein 1 0.03318
PCM1 pericentriolar material 1 0.03318
IGF1R insulin-like growth factor 1 receptor 0.03318
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.03318
FASLG Fas ligand (TNF superfamily, member 6) 0.03318
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.03318
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.03318
BCL10 B-cell CLL/lymphoma 10 0.03318
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 0.03318
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.03318
ANK2 ankyrin 2, neuronal 0.03318
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.03318
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.03318
FADD Fas (TNFRSF6)-associated via death domain 0.03318
PRKCZ protein kinase C, zeta 0.03318
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 0.03318
SDC4 syndecan 4 0.03318
PTK2B protein tyrosine kinase 2 beta 0.03318
TSC2 tuberous sclerosis 2 0.03318
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.03318
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.03318
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.03318
NPC1 Niemann-Pick disease, type C1 0.03318
HPSE heparanase 0.03318
EFNB1 ephrin-B1 0.03318
CD36 CD36 molecule (thrombospondin receptor) 0.03318
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.03318
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.03318
CSK c-src tyrosine kinase 0.03318
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.03318
DCC DCC netrin 1 receptor 0.03318
STOML3 stomatin (EPB72)-like 3 0.03318
EZR ezrin 0.03318
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.03318
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 0.03318
ITGA1 integrin, alpha 1 0.03318
TRAF2 TNF receptor-associated factor 2 0.03318
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 0.03318
BIRC3 baculoviral IAP repeat containing 3 0.03318
UMOD uromodulin 0.03318
BSG basigin (Ok blood group) 0.03318
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.03318
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.03318
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.03318
GSK3B glycogen synthase kinase 3 beta 0.03318
PDZK1 PDZ domain containing 1 0.03318
CCDC6 coiled-coil domain containing 6 0.03318
OPRD1 opioid receptor, delta 1 0.03318
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.03318
RET ret proto-oncogene 0.03318
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.03318
HMOX1 heme oxygenase 1 0.03318
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.03318
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.03318
NFAM1 NFAT activating protein with ITAM motif 1 0.03318
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 0.03318
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.03318
RHOQ ras homolog family member Q 0.03318
CD14 CD14 molecule 0.03318
EDNRB endothelin receptor type B 0.03318
DLG1 discs, large homolog 1 (Drosophila) 0.03318
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.03318
KRAS Kirsten rat sarcoma viral oncogene homolog 0.03318
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.03318
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.03318
TRADD TNFRSF1A-associated via death domain 0.03318
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.03318
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 0.03318
TNR tenascin R 0.03318
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.03318
STX2 syntaxin 2 0.03318
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.03318
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.03318
RTN4RL1 reticulon 4 receptor-like 1 0.03318
RTN4RL2 reticulon 4 receptor-like 2 0.03318
UTRN utrophin 0.03318
CD4 CD4 molecule 0.03318
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.03318
EPHB1 EPH receptor B1 0.03318