membrane protein intracellular domain proteolysis Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain. (Gene Ontology, GO_0031293)
External Link http://amigo.geneontology.org/amigo/term/GO:0031293
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Genes

17 genes participating in the membrane protein intracellular domain proteolysis biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
HM13 histocompatibility (minor) 13
MBTPS1 membrane-bound transcription factor peptidase, site 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
NCSTN nicastrin
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGFR nerve growth factor receptor
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHBDD1 rhomboid domain containing 1
SPPL2A signal peptide peptidase like 2A
SPPL2B signal peptide peptidase like 2B
SPPL2C signal peptide peptidase like 2C
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase