mellitus Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Similar Terms
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Genes

441 genes co-occuring with the biological term mellitus in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACACA acetyl-CoA carboxylase alpha
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACP1 acid phosphatase 1, soluble
ADA adenosine deaminase
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADM adrenomedullin
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHI1 Abelson helper integration site 1
AHSG alpha-2-HS-glycoprotein
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALPK1 alpha-kinase 1
ALPL alkaline phosphatase, liver/bone/kidney
ANGPT2 angiopoietin 2
ANGPTL4 angiopoietin-like 4
APLN apelin
APOA1 apolipoprotein A-I
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARG1 arginase 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ATF4 activating transcription factor 4
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
AVP arginine vasopressin
B2M beta-2-microglobulin
BCHE butyrylcholinesterase
BDNF brain-derived neurotrophic factor
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP7 bone morphogenetic protein 7
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BTC betacellulin
BTN2A1 butyrophilin, subfamily 2, member A1
C10ORF2 chromosome 10 open reading frame 2
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C5AR2 complement component 5a receptor 2
CAPN1 calpain 1, (mu/I) large subunit
CAPN10 calpain 10
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD163 CD163 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD4 CD4 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CETP cholesteryl ester transfer protein, plasma
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC16A C-type lectin domain family 16, member A
CLU clusterin
CNR1 cannabinoid receptor 1 (brain)
COL18A1 collagen, type XVIII, alpha 1
CP ceruloplasmin (ferroxidase)
CPB2 carboxypeptidase B2 (plasma)
CPT1A carnitine palmitoyltransferase 1A (liver)
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CST3 cystatin C
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DCAF17 DDB1 and CUL4 associated factor 17
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDIT3 DNA-damage-inducible transcript 3
DIO2 deiodinase, iodothyronine, type II
DLK1 delta-like 1 homolog (Drosophila)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPP4 dipeptidyl-peptidase 4
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELANE elastase, neutrophil expressed
ENHO energy homeostasis associated
ENO2 enolase 2 (gamma, neuronal)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ESAM endothelial cell adhesion molecule
ESR1 estrogen receptor 1
EXT2 exostosin glycosyltransferase 2
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FABP2 fatty acid binding protein 2, intestinal
FABP4 fatty acid binding protein 4, adipocyte
FADS3 fatty acid desaturase 3
FAIM2 Fas apoptotic inhibitory molecule 2
FASN fatty acid synthase
FFAR1 free fatty acid receptor 1
FGB fibrinogen beta chain
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF21 fibroblast growth factor 21
FGF23 fibroblast growth factor 23
FLT1 fms-related tyrosine kinase 1
FN3K fructosamine 3 kinase
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FST follistatin
FTL ferritin, light polypeptide
FTO fat mass and obesity associated
FXN frataxin
G6PC glucose-6-phosphatase, catalytic subunit
G6PD glucose-6-phosphate dehydrogenase
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAL galanin/GMAP prepropeptide
GAP43 growth associated protein 43
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GC group-specific component (vitamin D binding protein)
GCG glucagon
GCK glucokinase (hexokinase 4)
GGT1 gamma-glutamyltransferase 1
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GIPR gastric inhibitory polypeptide receptor
GLB1 galactosidase, beta 1
GLO1 glyoxalase I
GLP1R glucagon-like peptide 1 receptor
GLUL glutamate-ammonia ligase
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GPX3 glutathione peroxidase 3
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GYS1 glycogen synthase 1 (muscle)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAVCR1 hepatitis A virus cellular receptor 1
HBA1 hemoglobin, alpha 1
HDAC3 histone deacetylase 3
HEXB hexosaminidase B (beta polypeptide)
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HHEX hematopoietically expressed homeobox
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HINT1 histidine triad nucleotide binding protein 1
HLA-B major histocompatibility complex, class I, B
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGA1 high mobility group AT-hook 1
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HNF4A hepatocyte nuclear factor 4, alpha
HP haptoglobin
HPSE heparanase
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IDDM17 insulin-dependent diabetes mellitus 17
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL18 interleukin 18
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
ILF3 interleukin enhancer binding factor 3, 90kDa
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
INS insulin
INSR insulin receptor
IP6K1 inositol hexakisphosphate kinase 1
IRAK1 interleukin-1 receptor-associated kinase 1
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITLN1 intelectin 1 (galactofuranose binding)
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDR kinase insert domain receptor
KIF6 kinesin family member 6
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KLF11 Kruppel-like factor 11
LCAT lecithin-cholesterol acyltransferase
LCN2 lipocalin 2
LEP leptin
LEPQTL1 Leptin, serum levels of
LEPR leptin receptor
LGMN legumain
LIN28A lin-28 homolog A (C. elegans)
LIPC lipase, hepatic
LIPE lipase, hormone-sensitive
LMNA lamin A/C
LMX1A LIM homeobox transcription factor 1, alpha
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LTA lymphotoxin alpha
LTF lactotransferrin
LY75 lymphocyte antigen 75
MAPT microtubule-associated protein tau
MBL2 mannose-binding lectin (protein C) 2, soluble
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MEG3 maternally expressed 3 (non-protein coding)
MEST mesoderm specific transcript
MGP matrix Gla protein
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIOX myo-inositol oxygenase
MIR126 microRNA 126
MIR130A microRNA 130a
MIR143 microRNA 143
MIR144 microRNA 144
MIR145 microRNA 145
MIR155 microRNA 155
MIR16-1 microRNA 16-1
MIR222 microRNA 222
MIR518D microRNA 518d
MIRLET7A1 microRNA let-7a-1
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MT-TL1 tRNA
MT1A metallothionein 1A
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTNR1A melatonin receptor 1A
MTNR1B melatonin receptor 1B
NAMPT nicotinamide phosphoribosyltransferase
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
ND1
NEUROD1 neuronal differentiation 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
NUCB2 nucleobindin 2
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PAOX polyamine oxidase (exo-N4-amino)
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAX4 paired box 4
PAX6 paired box 6
PBX1 pre-B-cell leukemia homeobox 1
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCD1 programmed cell death 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDX1 pancreatic and duodenal homeobox 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PKLR pyruvate kinase, liver and RBC
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAGL1 pleiomorphic adenoma gene-like 1
PLAT plasminogen activator, tissue
PLTP phospholipid transfer protein
POLG polymerase (DNA directed), gamma
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRDX4 peroxiredoxin 4
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKCB protein kinase C, beta
PRTN3 proteinase 3
PTF1A pancreas specific transcription factor, 1a
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRN protein tyrosine phosphatase, receptor type, N
PTPRS protein tyrosine phosphatase, receptor type, S
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
REG3A regenerating islet-derived 3 alpha
REN renin
RETN resistin
RHD Rh blood group, D antigen
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX3 runt-related transcription factor 3
RXRA retinoid X receptor, alpha
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100B S100 calcium binding protein B
SELE selectin E
SELL selectin L
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP5 secreted frizzled-related protein 5
SHBG sex hormone-binding globulin
SHH sonic hedgehog
SIAE sialic acid acetylesterase
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SORCS1 sortilin-related VPS10 domain containing receptor 1
SOST sclerostin
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK1 serine peptidase inhibitor, Kazal type 1
STAT4 signal transducer and activator of transcription 4
STEAP4 STEAP family member 4
SUMO4 small ubiquitin-like modifier 4
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEK TEK tyrosine kinase, endothelial
TF transferrin
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFB1 transforming growth factor, beta 1
TLL1 tolloid-like 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TPM1 tropomyosin 1 (alpha)
TPO thyroid peroxidase
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TTR transthyretin
TXN thioredoxin
TXNIP thioredoxin interacting protein
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
USP36 ubiquitin specific peptidase 36
UTS2 urotensin 2
UTS2B urotensin 2B
UTS2R urotensin 2 receptor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIMP VCP-interacting membrane selenoprotein
VTN vitronectin
VWF von Willebrand factor
WFS1 Wolfram syndrome 1 (wolframin)
WNT5A wingless-type MMTV integration site family, member 5A
WNT5B wingless-type MMTV integration site family, member 5B
WRN Werner syndrome, RecQ helicase-like
ZFP57 ZFP57 zinc finger protein