melanoma Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A cell type cancer that has_material_basis_in abnormally proliferating cells derived_from melanocytes which are found in skin, the bowel and the eye. (Human Disease Ontology, DOID_1909)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0002861
Similar Terms
Downloads & Tools

Genes

61 genes associated with the melanoma phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
CDK10 cyclin-dependent kinase 10 2.14826
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 1.75058
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 1.75033
TYR tyrosinase 1.67051
FTO fat mass and obesity associated 1.53327
NCOA6 nuclear receptor coactivator 6 1.47227
SPATA33 spermatogenesis associated 33 1.4429
DEF8 differentially expressed in FDCP 8 homolog (mouse) 1.43453
BPIFA3 BPI fold containing family A, member 3 1.39815
AFG3L1P AFG3-like AAA ATPase 1, pseudogene 1.38455
ALS2CR12 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 1.35901
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 1.32793
MX2 MX dynamin-like GTPase 2 1.30781
ATM ATM serine/threonine kinase 1.30781
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.30315
MTAP methylthioadenosine phosphorylase 1.26545
MGMT O-6-methylguanine-DNA methyltransferase 1.24751
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1.20661
CLPTM1L CLPTM1-like 1.19958
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 1.16681
CDK5RAP1 CDK5 regulatory subunit associated protein 1 1.16299
PARP1 poly (ADP-ribose) polymerase 1 1.15743
PHF20 PHD finger protein 20 1.1348
SLC45A2 solute carrier family 45, member 2 1.12851
ANKRD11 ankyrin repeat domain 11 1.10754
ZNF276 zinc finger protein 276 1.02247
DPEP1 dipeptidase 1 (renal) 1.01883
FANCA Fanconi anemia, complementation group A 1.01337
ANXA9 annexin A9 1.00059
CSMD1 CUB and Sushi multiple domains 1 0.909246
CPNE7 copine VII 0.90398
RALY RALY heterogeneous nuclear ribonucleoprotein 0.85521
PRMT8 protein arginine methyltransferase 8 0.818279
COTL1 coactosin-like F-actin binding protein 1 0.812214
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.787244
DOCK8 dedicator of cytokinesis 8 0.777194
SAFB2 scaffold attachment factor B2 0.772842
SOX6 SRY (sex determining region Y)-box 6 0.767696
RPS7P5 ribosomal protein S7 pseudogene 5 0.744535
NTN1 netrin 1 0.732349
TOX2 TOX high mobility group box family member 2 0.724872
PPA2 pyrophosphatase (inorganic) 2 0.717942
PARD3B par-3 family cell polarity regulator beta 0.714661
DNAH9 dynein, axonemal, heavy chain 9 0.696351
PTPRG protein tyrosine phosphatase, receptor type, G 0.693745
ZFAT zinc finger and AT hook domain containing 0.693425
ELMO1 engulfment and cell motility 1 0.693105
E2F1 E2F transcription factor 1 0.689964
ERO1L ERO1-like (S. cerevisiae) 0.682247
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.681679
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 0.671914
GRM7 glutamate receptor, metabotropic 7 0.671341
KIF16B kinesin family member 16B 0.629837
HDAC4 histone deacetylase 4 0.628153
PCDH15 protocadherin-related 15 0.623659
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.610315
LST1 leukocyte specific transcript 1 0.606913
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.59159
CLEC4M C-type lectin domain family 4, member M 0.581031
STK4 serine/threonine kinase 4 0.579744
KIFC3 kinesin family member C3 0.573685