mda-mb-453 cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Human breast carcinoma cell line; established from an effusion of a 48-year-old woman with breast carcinoma in 1976. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001908)
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Genes

158 proteins co-occuring with the tissue mda-mb-453 cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
ERBB2 erb-b2 receptor tyrosine kinase 2 2.13098
ERBB4 erb-b2 receptor tyrosine kinase 4 1.70595
ERBB3 erb-b2 receptor tyrosine kinase 3 1.70545
EGFR epidermal growth factor receptor 1.47288
AR androgen receptor 1.15096
EIF3A eukaryotic translation initiation factor 3, subunit A 1.11995
NRG2 neuregulin 2 1.11331
ESR1 estrogen receptor 1 1.08148
FGFR4 fibroblast growth factor receptor 4 1.04137
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.04137
ARV1 ARV1 homolog (S. cerevisiae) 0.978049
GRB2 growth factor receptor-bound protein 2 0.964199
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.952116
CCND1 cyclin D1 0.924623
MTMR11 myotubularin related protein 11 0.907109
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 0.881204
RB1CC1 RB1-inducible coiled-coil 1 0.87782
SPHK2 sphingosine kinase 2 0.865155
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.852106
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 0.843286
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 0.840349
S1PR4 sphingosine-1-phosphate receptor 4 0.829872
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.818994
IGSF11 immunoglobulin superfamily, member 11 0.817322
BAX BCL2-associated X protein 0.806047
BTC betacellulin 0.803961
CDK4 cyclin-dependent kinase 4 0.800208
SPHK1 sphingosine kinase 1 0.733912
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 0.724453
PARP1 poly (ADP-ribose) polymerase 1 0.718292
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.687592
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.683919
FOXA1 forkhead box A1 0.673321
PRLR prolactin receptor 0.657054
HELLS helicase, lymphoid-specific 0.655836
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.655024
HBEGF heparin-binding EGF-like growth factor 0.643669
AREG amphiregulin 0.629506
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.628697
TP53 tumor protein p53 0.62385
CDC14A cell division cycle 14A 0.609735
NRD1 nardilysin (N-arginine dibasic convertase) 0.60893
TXNL1 thioredoxin-like 1 0.601686
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.59405
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.590839
ZBTB10 zinc finger and BTB domain containing 10 0.588832
IPO7 importin 7 0.583621
ANXA5 annexin A5 0.58322
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.569222
CD24 CD24 molecule 0.563637
PTPRK protein tyrosine phosphatase, receptor type, K 0.550503
DUSP10 dual specificity phosphatase 10 0.546533
CDC25B cell division cycle 25B 0.536229
TOPBP1 topoisomerase (DNA) II binding protein 1 0.534647
RECQL4 RecQ protein-like 4 0.527928
BIRC5 baculoviral IAP repeat containing 5 0.525955
ATF3 activating transcription factor 3 0.519253
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.518859
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.517284
CDKN3 cyclin-dependent kinase inhibitor 3 0.500007
TDGF1 teratocarcinoma-derived growth factor 1 0.492182
CDC16 cell division cycle 16 0.487886
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.468048
PTPRA protein tyrosine phosphatase, receptor type, A 0.464174
GNPDA1 glucosamine-6-phosphate deaminase 1 0.458373
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.456828
RARB retinoic acid receptor, beta 0.456442
PSPH phosphoserine phosphatase 0.447192
NRG1 neuregulin 1 0.446807
DUSP4 dual specificity phosphatase 4 0.443731
KIAA1524 KIAA1524 0.440274
DPP9 dipeptidyl-peptidase 9 0.43414
CLCN2 chloride channel, voltage-sensitive 2 0.432991
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.432225
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.431077
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.429547
TRIP10 thyroid hormone receptor interactor 10 0.42649
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.425344
ENG endoglin 0.423054
GLDC glycine dehydrogenase (decarboxylating) 0.421148
CCNG2 cyclin G2 0.420766
CDC37 cell division cycle 37 0.417718
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.413151
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.409351
LMO1 LIM domain only 1 (rhombotin 1) 0.407073
ZHX2 zinc fingers and homeoboxes 2 0.405176
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.396465
DPP8 dipeptidyl-peptidase 8 0.394197
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.393064
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.388535
SCGB2A2 secretoglobin, family 2A, member 2 0.388535
CD44 CD44 molecule (Indian blood group) 0.388158
DDB2 damage-specific DNA binding protein 2, 48kDa 0.382884
BACE2 beta-site APP-cleaving enzyme 2 0.380627
PTEN phosphatase and tensin homolog 0.377996
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.366007
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.36302
ADAM15 ADAM metallopeptidase domain 15 0.352598
TFDP3 transcription factor Dp family, member 3 0.351114
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.348148
PSAT1 phosphoserine aminotransferase 1 0.346298
BIRC2 baculoviral IAP repeat containing 2 0.345188
IGHV3-30 immunoglobulin heavy variable 3-30 0.338177
INSIG1 insulin induced gene 1 0.337808
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.33413
CDC25C cell division cycle 25C 0.328994
NEU3 sialidase 3 (membrane sialidase) 0.326798
MIR203A microRNA 203a 0.32497
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.319863
CCNE2 cyclin E2 0.312232
PRSS8 protease, serine, 8 0.303559
DIABLO diablo, IAP-binding mitochondrial protein 0.298165
MMP2 matrix metallopeptidase 2 0.297447
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.296013
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.285671
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 0.284962
RB1 retinoblastoma 1 0.282483
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.281776
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.280717
SPDEF SAM pointed domain containing ETS transcription factor 0.279307
TOP2B topoisomerase (DNA) II beta 180kDa 0.2779
ADAM9 ADAM metallopeptidase domain 9 0.277549
FGFR1 fibroblast growth factor receptor 1 0.277197
COPS5 COP9 signalosome subunit 5 0.275444
HVCN1 hydrogen voltage gated channel 1 0.2723
XBP1 X-box binding protein 1 0.270214
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.266413
TEK TEK tyrosine kinase, endothelial 0.262304
BRCA1 breast cancer 1, early onset 0.259929
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.258917
LPAR2 lysophosphatidic acid receptor 2 0.257572
CSN2 casein beta 0.251279
IGFBP7 insulin-like growth factor binding protein 7 0.250301
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.248683
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.247399
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.247079
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.246124
MUC1 mucin 1, cell surface associated 0.241438
PGR progesterone receptor 0.23961
PLK4 polo-like kinase 4 0.237513
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.234878
BCL2L1 BCL2-like 1 0.233162
HSPB1 heat shock 27kDa protein 1 0.232039
RRAS related RAS viral (r-ras) oncogene homolog 0.229032
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.227186
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.226411
H3F3B H3 histone, family 3B (H3.3B) 0.223419
H3F3A H3 histone, family 3A 0.223419
CLCA2 chloride channel accessory 2 0.222938
TIAM1 T-cell lymphoma invasion and metastasis 1 0.222938
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.221291
MTM1 myotubularin 1 0.217762
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.217346
HDAC9 histone deacetylase 9 0.216126
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.214765
FOXM1 forkhead box M1 0.214576
KDM1A lysine (K)-specific demethylase 1A 0.214388
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.212413