map Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

439 genes co-occuring with the biological term map in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADAM17 ADAM metallopeptidase domain 17
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
ADRA2A adrenoceptor alpha 2A
ADRB2 adrenoceptor beta 2, surface
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALCAM activated leukocyte cell adhesion molecule
ALOX15 arachidonate 15-lipoxygenase
ALPK1 alpha-kinase 1
ALYREF Aly/REF export factor
ANGPT1 angiopoietin 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APLP1 amyloid beta (A4) precursor-like protein 1
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AREG amphiregulin
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATF2 activating transcription factor 2
ATG14 autophagy related 14
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
ATR ATR serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
B2M beta-2-microglobulin
BAG1 BCL2-associated athanogene
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BPIFB1 BPI fold containing family B, member 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRAP BRCA1 associated protein
BRCA1 breast cancer 1, early onset
BSG basigin (Ok blood group)
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
BTC betacellulin
C3ORF33 chromosome 3 open reading frame 33
CALCA calcitonin-related polypeptide alpha
CAMP cathelicidin antimicrobial peptide
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL13 chemokine (C-C motif) ligand 13
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CD46 CD46 molecule, complement regulatory protein
CD59 CD59 molecule, complement regulatory protein
CD6 CD6 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC42 cell division cycle 42
CDC7 cell division cycle 7
CDK12 cyclin-dependent kinase 12
CDKL3 cyclin-dependent kinase-like 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDT1 chromatin licensing and DNA replication factor 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPE centromere protein E, 312kDa
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHL1 cell adhesion molecule L1-like
CHN1 chimerin 1
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHTOP chromatin target of PRMT1
CIB1 calcium and integrin binding 1 (calmyrin)
CLECL1 C-type lectin-like 1
CMA1 chymase 1, mast cell
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNR2 cannabinoid receptor 2 (macrophage)
COL6A5 collagen, type VI, alpha 5
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREB1 cAMP responsive element binding protein 1
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSMD3 CUB and Sushi multiple domains 3
CTGF connective tissue growth factor
CTSB cathepsin B
CTSK cathepsin K
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CYBB cytochrome b-245, beta polypeptide
CYTH2 cytohesin 2
DDR1 discoidin domain receptor tyrosine kinase 1
DEFB4A defensin, beta 4A
DICER1 dicer 1, ribonuclease type III
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
E2F1 E2F transcription factor 1
EDN1 endothelin 1
EFNB1 ephrin-B1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF3A eukaryotic translation initiation factor 3, subunit A
ELANE elastase, neutrophil expressed
ELAVL1 ELAV like RNA binding protein 1
ELK1 ELK1, member of ETS oncogene family
EPHA2 EPH receptor A2
EPHB3 EPH receptor B3
EPHB6 EPH receptor B6
ERBB2 erb-b2 receptor tyrosine kinase 2
EREG epiregulin
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
ETM2 essential tremor 2
ETNK1 ethanolamine kinase 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV1 ets variant 1
ETV4 ets variant 4
EZR ezrin
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FAS Fas cell surface death receptor
FASN fatty acid synthase
FGF2 fibroblast growth factor 2 (basic)
FHOD1 formin homology 2 domain containing 1
FKBP5 FK506 binding protein 5
FOXP2 forkhead box P2
FRA1E fragile site, aphidicolin type, common, fra(1)(p21.2)
FRS3 fibroblast growth factor receptor substrate 3
FSHR follicle stimulating hormone receptor
GAB2 GRB2-associated binding protein 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GANC glucosidase, alpha; neutral C
GDNF glial cell derived neurotrophic factor
GH1 growth hormone 1
GHRHR growth hormone releasing hormone receptor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLRA2 glycine receptor, alpha 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPER1 G protein-coupled estrogen receptor 1
GREM1 gremlin 1, DAN family BMP antagonist
GSPT1 G1 to S phase transition 1
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
HBEGF heparin-binding EGF-like growth factor
HCAR3 hydroxycarboxylic acid receptor 3
HDAC6 histone deacetylase 6
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST3H3 histone cluster 3, H3
HLA-C major histocompatibility complex, class I, C
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXA1 homeobox A1
HRAS Harvey rat sarcoma viral oncogene homolog
HSF4 heat shock transcription factor 4
HSPB1 heat shock 27kDa protein 1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP5 insulin-like growth factor binding protein 5
IGHE immunoglobulin heavy constant epsilon
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL11 interleukin 11
IL13 interleukin 13
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL33 interleukin 33
IL6 interleukin 6
INHBA inhibin, beta A
IQGAP1 IQ motif containing GTPase activating protein 1
IRF3 interferon regulatory factor 3
IRF5 interferon regulatory factor 5
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB1BP1 integrin beta 1 binding protein 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KDR kinase insert domain receptor
KIAA0196 KIAA0196
KIF4A kinesin family member 4A
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KISS1 KiSS-1 metastasis-suppressor
KNG1 kininogen 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KSR2 kinase suppressor of ras 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LIPC lipase, hepatic
LTC4S leukotriene C4 synthase
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAP2 microtubule-associated protein 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
METAP1D methionyl aminopeptidase type 1D (mitochondrial)
MGST1 microsomal glutathione S-transferase 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIP major intrinsic protein of lens fiber
MIR200C microRNA 200c
MLANA melan-A
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MOG myelin oligodendrocyte glycoprotein
MUC1 mucin 1, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUTYH mutY homolog
MX2 MX dynamin-like GTPase 2
MXD1 MAX dimerization protein 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYP3 myopia 3 (high grade, autosomal dominant)
NBN nibrin
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NDFIP1 Nedd4 family interacting protein 1
NDFIP2 Nedd4 family interacting protein 2
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NME1 NME/NM23 nucleoside diphosphate kinase 1
NONO non-POU domain containing, octamer-binding
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX4 NADPH oxidase 4
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPY neuropeptide Y
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUMA1 nuclear mitotic apparatus protein 1
NUMB numb homolog (Drosophila)
NXF1 nuclear RNA export factor 1
ODC1 ornithine decarboxylase 1
OPRM1 opioid receptor, mu 1
PADI1 peptidyl arginine deiminase, type I
PADI3 peptidyl arginine deiminase, type III
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAX5 paired box 5
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFB platelet-derived growth factor beta polypeptide
PDX1 pancreatic and duodenal homeobox 1
PEA15 phosphoprotein enriched in astrocytes 15
PEBP1 phosphatidylethanolamine binding protein 1
PF4 platelet factor 4
PHB prohibitin
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKP2 plakophilin 2
PLAT plasminogen activator, tissue
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRC1 protein regulator of cytokinesis 1
PRIMA1 proline rich membrane anchor 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCH protein kinase C, eta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRL prolactin
PRNP prion protein
PROCR protein C receptor, endothelial
PROM1 prominin 1
PRSS1 protease, serine, 1 (trypsin 1)
PSEN1 presenilin 1
PSPC1 paraspeckle component 1
PTEN phosphatase and tensin homolog
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTTG1 pituitary tumor-transforming 1
PYGM phosphorylase, glycogen, muscle
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RB1 retinoblastoma 1
RBM17 RNA binding motif protein 17
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REST RE1-silencing transcription factor
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RIT1 Ras-like without CAAX 1
RIT2 Ras-like without CAAX 2
RPS3 ribosomal protein S3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRAS related RAS viral (r-ras) oncogene homolog
RUNX2 runt-related transcription factor 2
S100A11 S100 calcium binding protein A11
S100A9 S100 calcium binding protein A9
S1PR1 sphingosine-1-phosphate receptor 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SDC2 syndecan 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFPQ splicing factor proline/glutamine-rich
SGSM3 small G protein signaling modulator 3
SHH sonic hedgehog
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMYD3 SET and MYND domain containing 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOAT1 sterol O-acyltransferase 1
SOCS3 suppressor of cytokine signaling 3
SOX5 SRY (sex determining region Y)-box 5
SP1 Sp1 transcription factor
SPHK1 sphingosine kinase 1
SPI1 Spi-1 proto-oncogene
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SS18 synovial sarcoma translocation, chromosome 18
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SST somatostatin
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SUB1 SUB1 homolog (S. cerevisiae)
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SYK spleen tyrosine kinase
SYNM synemin, intermediate filament protein
TAC1 tachykinin, precursor 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TP73 tumor protein p73
TPP1 tripeptidyl peptidase I
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UMOD uromodulin
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
WNK4 WNK lysine deficient protein kinase 4
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZEB1 zinc finger E-box binding homeobox 1
ZFP36 ZFP36 ring finger protein
ZMPSTE24 zinc metallopeptidase STE24