mammary Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

458 genes co-occuring with the biological term mammary in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADAM15 ADAM metallopeptidase domain 15
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
AGTR2 angiotensin II receptor, type 2
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALX4 ALX homeobox 4
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANGPTL4 angiopoietin-like 4
ANKRD30A ankyrin repeat domain 30A
ANXA1 annexin A1
ANXA8 annexin A8
APC adenomatous polyposis coli
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AREG amphiregulin
ARG2 arginase 2
ARHGAP5 Rho GTPase activating protein 5
ARRB1 arrestin, beta 1
ARTN artemin
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATP7B ATPase, Cu++ transporting, beta polypeptide
AURKA aurora kinase A
BAX BCL2-associated X protein
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BHLHA15 basic helix-loop-helix family, member a15
BIN1 bridging integrator 1
BMF Bcl2 modifying factor
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTG2 BTG family, member 2
BTN1A1 butyrophilin, subfamily 1, member A1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAMP cathelicidin antimicrobial peptide
CAV1 caveolin 1, caveolae protein, 22kDa
CCL16 chemokine (C-C motif) ligand 16
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CCNE1 cyclin E1
CD151 CD151 molecule (Raph blood group)
CD24 CD24 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD82 CD82 molecule
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CGB5 chorionic gonadotropin, beta polypeptide 5
CHEK2 checkpoint kinase 2
CHGA chromogranin A
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKS1B CDC28 protein kinase regulatory subunit 1B
CKS2 CDC28 protein kinase regulatory subunit 2
CLDN4 claudin 4
CLEC10A C-type lectin domain family 10, member A
CP ceruloplasmin (ferroxidase)
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRABP2 cellular retinoic acid binding protein 2
CREBBP CREB binding protein
CSK c-src tyrosine kinase
CSN2 casein beta
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSE cathepsin E
CTTN cortactin
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAPK1 death-associated protein kinase 1
DDIT3 DNA-damage-inducible transcript 3
DKC1 dyskeratosis congenita 1, dyskerin
DLC1 DLC1 Rho GTPase activating protein
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
EDAR ectodysplasin A receptor
EDN1 endothelin 1
EDN2 endothelin 2
EDN3 endothelin 3
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELAVL1 ELAV like RNA binding protein 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELF5 E74-like factor 5 (ets domain transcription factor)
ELN elastin
EP300 E1A binding protein p300
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERP29 endoplasmic reticulum protein 29
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV1 ets variant 1
ETV6 ets variant 6
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM89B family with sequence similarity 89, member B
FCAR Fc fragment of IgA receptor
FFAR2 free fatty acid receptor 2
FFAR3 free fatty acid receptor 3
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FLOT2 flotillin 2
FN1 fibronectin 1
FOXA1 forkhead box A1
FOXE1 forkhead box E1
FOXM1 forkhead box M1
FOXO3 forkhead box O3
GAB2 GRB2-associated binding protein 2
GATA3 GATA binding protein 3
GBA glucosidase, beta, acid
GBP1 guanylate binding protein 1, interferon-inducible
GDE1 glycerophosphodiester phosphodiesterase 1
GDF15 growth differentiation factor 15
GFRA1 GDNF family receptor alpha 1
GFRA3 GDNF family receptor alpha 3
GH1 growth hormone 1
GH2 growth hormone 2
GHR growth hormone receptor
GHRHR growth hormone releasing hormone receptor
GLYCAM1 glycosylation dependent cell adhesion molecule 1 (pseudogene)
GMNN geminin, DNA replication inhibitor
GNAS GNAS complex locus
GPER1 G protein-coupled estrogen receptor 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRM1 glutamate receptor, metabotropic 1
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
GSTA4 glutathione S-transferase alpha 4
GSTK1 glutathione S-transferase kappa 1
GSTP1 glutathione S-transferase pi 1
H2AFZ H2A histone family, member Z
HBEGF heparin-binding EGF-like growth factor
HCAR2 hydroxycarboxylic acid receptor 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOXA1 homeobox A1
HOXB2 homeobox B2
HRAS Harvey rat sarcoma viral oncogene homolog
HRH4 histamine receptor H4
HRNR hornerin
HUNK hormonally up-regulated Neu-associated kinase
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDE insulin-degrading enzyme
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL10 interleukin 10
IL17B interleukin 17B
IL17RB interleukin 17 receptor B
IL1B interleukin 1, beta
IL6ST interleukin 6 signal transducer
ILK integrin-linked kinase
ING4 inhibitor of growth family, member 4
INHBA inhibin, beta A
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IQGAP1 IQ motif containing GTPase activating protein 1
IRF5 interferon regulatory factor 5
IRF6 interferon regulatory factor 6
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGA8 integrin, alpha 8
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
JUP junction plakoglobin
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM3A lysine (K)-specific demethylase 3A
KEAP1 kelch-like ECH-associated protein 1
KISS1R KISS1 receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KRT8 keratin 8, type II
LACRT lacritin
LALBA lactalbumin, alpha-
LAMA3 laminin, alpha 3
LBH limb bud and heart development
LDB1 LIM domain binding 1
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LIPG lipase, endothelial
LMO4 LIM domain only 4
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LTB4R2 leukotriene B4 receptor 2
LTBP4 latent transforming growth factor beta binding protein 4
LTF lactotransferrin
MAGEC1 melanoma antigen family C1
MAGED1 melanoma antigen family D1
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED1 mediator complex subunit 1
MED22 mediator complex subunit 22
MELK maternal embryonic leucine zipper kinase
MET MET proto-oncogene, receptor tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MGMT O-6-methylguanine-DNA methyltransferase
MIER3 mesoderm induction early response 1, family member 3
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR18A microRNA 18a
MIR200A microRNA 200a
MIR200C microRNA 200c
MIR221 microRNA 221
MIR222 microRNA 222
MIR375 microRNA 375
MIR93 microRNA 93
MKI67 marker of proliferation Ki-67
MKL1 megakaryoblastic leukemia (translocation) 1
MKL2 MKL/myocardin-like 2
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MST1R macrophage stimulating 1 receptor
MTA3 metastasis associated 1 family, member 3
MTDH metadherin
MTNR1A melatonin receptor 1A
MTVR2 mouse mammary tumor virus receptor homolog 2
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA2 nuclear receptor coactivator 2
NCOA3 nuclear receptor coactivator 3
NEK2 NIMA-related kinase 2
NEO1 neogenin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX2-1 NK2 homeobox 1
NKX2-5 NK2 homeobox 5
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH3 notch 3
NOTCH4 notch 4
NOX4 NADPH oxidase 4
NQO1 NAD(P)H dehydrogenase, quinone 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRG1 neuregulin 1
NRG3 neuregulin 3
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUMA1 nuclear mitotic apparatus protein 1
NUMB numb homolog (Drosophila)
OGG1 8-oxoguanine DNA glycosylase
OXTR oxytocin receptor
PADI2 peptidyl arginine deiminase, type II
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PALB2 partner and localizer of BRCA2
PAX5 paired box 5
PDPK1 3-phosphoinositide dependent protein kinase 1
PELP1 proline, glutamate and leucine rich protein 1
PGR progesterone receptor
PGRMC1 progesterone receptor membrane component 1
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCD1 phospholipase C, delta 1
PLCD3 phospholipase C, delta 3
PLIN2 perilipin 2
PON2 paraoxonase 2
POSTN periostin, osteoblast specific factor
POU1F1 POU class 1 homeobox 1
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCB protein kinase C, beta
PRL prolactin
PRLR prolactin receptor
PTEN phosphatase and tensin homolog
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRJ protein tyrosine phosphatase, receptor type, J
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHOA ras homolog family member A
RLIM ring finger protein, LIM domain interacting
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RORA RAR-related orphan receptor A
RUNX2 runt-related transcription factor 2
RUNX3 runt-related transcription factor 3
S100A7 S100 calcium binding protein A7
SCGB2A2 secretoglobin, family 2A, member 2
SCGB3A1 secretoglobin, family 3A, member 1
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SCRIB scribbled planar cell polarity protein
SDC3 syndecan 3
SDF2 stromal cell-derived factor 2
SDF4 stromal cell derived factor 4
SEPT9 septin 9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFRP2 secreted frizzled-related protein 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRT1 sirtuin 1
SIX1 SIX homeobox 1
SKIL SKI-like proto-oncogene
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SND1 staphylococcal nuclease and tudor domain containing 1
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOD3 superoxide dismutase 3, extracellular
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
SP1 Sp1 transcription factor
SPDEF SAM pointed domain containing ETS transcription factor
SPP1 secreted phosphoprotein 1
SPRY2 sprouty homolog 2 (Drosophila)
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STK11 serine/threonine kinase 11
STX1A syntaxin 1A (brain)
STX2 syntaxin 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SYK spleen tyrosine kinase
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDGF1 teratocarcinoma-derived growth factor 1
TERT telomerase reverse transcriptase
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFF1 trefoil factor 1
TFF2 trefoil factor 2
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TGM2 transglutaminase 2
THRA thyroid hormone receptor, alpha
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TJP1 tight junction protein 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNC tenascin C
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNK2 tyrosine kinase, non-receptor, 2
TNN tenascin N
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TRAF2 TNF receptor-associated factor 2
TRIM33 tripartite motif containing 33
TTF1 transcription termination factor, RNA polymerase I
TUBB3 tubulin, beta 3 class III
TWIST1 twist family bHLH transcription factor 1
TXNRD2 thioredoxin reductase 2
UBE3A ubiquitin protein ligase E3A
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WISP3 WNT1 inducible signaling pathway protein 3
WNT1 wingless-type MMTV integration site family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
WT1 Wilms tumor 1
WWC1 WW and C2 domain containing 1
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1
ZFAS1 ZNFX1 antisense RNA 1
ZFHX3 zinc finger homeobox 3
ZFP36 ZFP36 ring finger protein
ZNF217 zinc finger protein 217