malaria Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle. (Human Disease Ontology, DOID_12365)
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Genes

740 genes co-occuring with the disease malaria in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
DHFR dihydrofolate reductase 2.42221
NANP N-acetylneuraminic acid phosphatase 2.3706
G6PD glucose-6-phosphate dehydrogenase 2.1967
CD36 CD36 molecule (thrombospondin receptor) 2.1739
SCARB2 scavenger receptor class B, member 2 2.15148
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.12023
SCARB1 scavenger receptor class B, member 1 2.07578
KRT83 keratin 83, type II 1.98668
CD4 CD4 molecule 1.96942
KDR kinase insert domain receptor 1.92623
TNF tumor necrosis factor 1.77315
ICAM1 intercellular adhesion molecule 1 1.73641
MCF2 MCF.2 cell line derived transforming sequence 1.68362
DHPS deoxyhypusine synthase 1.56311
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 1.55823
DHODH dihydroorotate dehydrogenase (quinone) 1.55779
CD2 CD2 molecule 1.4057
IL10 interleukin 10 1.40264
HPR haptoglobin-related protein 1.40176
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1.39914
HP haptoglobin 1.38734
TLR9 toll-like receptor 9 1.3821
GSR glutathione reductase 1.3385
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 1.29352
RPAP3 RNA polymerase II associated protein 3 1.28566
HLA-B major histocompatibility complex, class I, B 1.25037
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.21002
ALB albumin 1.19921
TRIM37 tripartite motif containing 37 1.17851
EPB41 erythrocyte membrane protein band 4.1 1.16735
HPGDS hematopoietic prostaglandin D synthase 1.15709
OXSM 3-oxoacyl-ACP synthase, mitochondrial 1.1541
SCN3A sodium channel, voltage gated, type III alpha subunit 1.149
GYPC glycophorin C (Gerbich blood group) 1.14645
MYD88 myeloid differentiation primary response 88 1.13501
HBB hemoglobin, beta 1.12108
FTH1 ferritin, heavy polypeptide 1 1.1173
GYPA glycophorin A (MNS blood group) 1.10216
FTL ferritin, light polypeptide 1.10216
FYB FYN binding protein 1.10006
GYPE glycophorin E (MNS blood group) 1.09713
TFRC transferrin receptor 1.09419
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.09167
IL4 interleukin 4 1.08915
SCN8A sodium channel, voltage gated, type VIII alpha subunit 1.08831
ORC1 origin recognition complex, subunit 1 1.08747
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.06102
TLR2 toll-like receptor 2 1.05345
CXCL10 chemokine (C-X-C motif) ligand 10 1.05219
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 1.05051
CRP C-reactive protein, pentraxin-related 1.04672
TLR4 toll-like receptor 4 1.04251
SELE selectin E 1.03493
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.02735
SALL1 spalt-like transcription factor 1 1.02482
PKLR pyruvate kinase, liver and RBC 1.01343
FXYD1 FXYD domain containing ion transport regulator 1 1.01343
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 1.00879
VNN1 vanin 1 0.994861
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.993596
IL2 interleukin 2 0.987271
CAT catalase 0.986007
TF transferrin 0.984743
FOXP3 forkhead box P3 0.978426
GLRXP3 glutaredoxin (thioltransferase) pseudogene 3 0.97086
SRM spermidine synthase 0.967502
SOD2 superoxide dismutase 2, mitochondrial 0.967083
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.964567
VCAM1 vascular cell adhesion molecule 1 0.962472
DOHH deoxyhypusine hydroxylase/monooxygenase 0.959542
HAMP hepcidin antimicrobial peptide 0.954525
NSL1 NSL1, MIS12 kinetochore complex component 0.954525
ZAN zonadhesin (gene/pseudogene) 0.947435
VNN2 vanin 2 0.946603
ANK1 ankyrin 1, erythrocytic 0.945354
LTA lymphotoxin alpha 0.936214
HBD hemoglobin, delta 0.933313
ACHE acetylcholinesterase (Yt blood group) 0.925865
IL6 interleukin 6 0.921736
IL1B interleukin 1, beta 0.917199
IFNG interferon, gamma 0.910199
PRF1 perforin 1 (pore forming protein) 0.898693
HMOX1 heme oxygenase 1 0.895
CXCL9 chemokine (C-X-C motif) ligand 9 0.894179
GSTA1 glutathione S-transferase alpha 1 0.877376
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.876148
WARS tryptophanyl-tRNA synthetase 0.874919
IPP intracisternal A particle-promoted polypeptide 0.874919
GSTA3 glutathione S-transferase alpha 3 0.873281
GSTA2 glutathione S-transferase alpha 2 0.871643
GSTA4 glutathione S-transferase alpha 4 0.870415
FDXR ferredoxin reductase 0.863456
GFER growth factor, augmenter of liver regeneration 0.862228
STOM stomatin 0.861818
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.857315
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.857315
TYMS thymidylate synthetase 0.856497
LIPJ lipase, family member J 0.856087
COG8 component of oligomeric golgi complex 8 0.852811
ADA adenosine deaminase 0.834378
BTBD7 BTB (POZ) domain containing 7 0.831508
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.823718
CCL3 chemokine (C-C motif) ligand 3 0.823718
GNG8 guanine nucleotide binding protein (G protein), gamma 8 0.818796
NONO non-POU domain containing, octamer-binding 0.818385
PIR pirin (iron-binding nuclear protein) 0.816334
CD81 CD81 molecule 0.815924
CMC2 C-x(9)-C motif containing 2 0.815104
CD1D CD1d molecule 0.813462
TGFB1 transforming growth factor, beta 1 0.812232
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.805667
CD79A CD79a molecule, immunoglobulin-associated alpha 0.804026
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.795002
LAP3 leucine aminopeptidase 3 0.78066
CD69 CD69 molecule 0.775341
HBE1 hemoglobin, epsilon 1 0.772887
IFNGR1 interferon gamma receptor 1 0.770435
IL7R interleukin 7 receptor 0.770027
MGAM maltase-glucoamylase 0.768393
HSPA4 heat shock 70kDa protein 4 0.767576
ANGPT1 angiopoietin 1 0.765943
HPX hemopexin 0.763902
HLA-C major histocompatibility complex, class I, C 0.762678
PKM pyruvate kinase, muscle 0.761862
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.759824
HM13 histocompatibility (minor) 13 0.751271
NOS2 nitric oxide synthase 2, inducible 0.745578
GPX1 glutathione peroxidase 1 0.739082
ALPP alkaline phosphatase, placental 0.735433
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.735027
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.735027
AMD1 adenosylmethionine decarboxylase 1 0.734622
LPO lactoperoxidase 0.721673
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.719654
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.71925
PANK1 pantothenate kinase 1 0.717635
PROCR protein C receptor, endothelial 0.714811
ODC1 ornithine decarboxylase 1 0.714408
SKA3 spindle and kinetochore associated complex subunit 3 0.713601
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.713198
NELFCD negative elongation factor complex member C/D 0.712392
GPX5 glutathione peroxidase 5 0.712392
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.711183
POR P450 (cytochrome) oxidoreductase 0.709572
GPX4 glutathione peroxidase 4 0.709169
HLA-A major histocompatibility complex, class I, A 0.707559
ANGPT2 angiopoietin 2 0.702732
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.701526
CTSC cathepsin C 0.700722
CTSD cathepsin D 0.699919
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.695905
NCR3 natural cytotoxicity triggering receptor 3 0.694301
HBA1 hemoglobin, alpha 1 0.693499
LCN8 lipocalin 8 0.688692
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.687491
HRH1 histamine receptor H1 0.686691
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.686691
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.686691
CHIT1 chitinase 1 (chitotriosidase) 0.685491
CFP complement factor properdin 0.683892
IL1A interleukin 1, alpha 0.683493
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.680697
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.680697
ESAM endothelial cell adhesion molecule 0.680297
CD86 CD86 molecule 0.679898
CSPP1 centrosome and spindle pole associated protein 1 0.678302
VWF von Willebrand factor 0.673917
VARS valyl-tRNA synthetase 0.673518
HBA2 hemoglobin, alpha 2 0.670333
ALPL alkaline phosphatase, liver/bone/kidney 0.665563
KARS lysyl-tRNA synthetase 0.665166
IL27RA interleukin 27 receptor, alpha 0.663975
ALPPL2 alkaline phosphatase, placental-like 2 0.656441
CLEC9A C-type lectin domain family 9, member A 0.654858
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.654067
ANXA4 annexin A4 0.654067
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.644192
MID2 midline 2 0.636315
PRDX2 peroxiredoxin 2 0.631205
ANXA5 annexin A5 0.629635
SLC22A18 solute carrier family 22, member 18 0.62885
DMTN dematin actin binding protein 0.623751
IGHV3-30 immunoglobulin heavy variable 3-30 0.622575
ADSL adenylosuccinate lyase 0.6214
CD80 CD80 molecule 0.619442
EPGN epithelial mitogen 0.617094
RHOBTB2 Rho-related BTB domain containing 2 0.613574
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 0.613183
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.612401
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.610057
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.60108
NME1-NME2 NME1-NME2 readthrough 0.59874
TIGD1 tigger transposable element derived 1 0.595233
C5AR1 complement component 5a receptor 1 0.594454
OAZ1 ornithine decarboxylase antizyme 1 0.590558
CCL2 chemokine (C-C motif) ligand 2 0.589779
TPT1 tumor protein, translationally-controlled 1 0.58939
PGD phosphogluconate dehydrogenase 0.588222
CD27 CD27 molecule 0.585497
CXCR3 chemokine (C-X-C motif) receptor 3 0.585497
DEFB107B defensin, beta 107B 0.585108
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 0.581217
DUT deoxyuridine triphosphatase 0.576161
SRI sorcin 0.574605
GGPS1 geranylgeranyl diphosphate synthase 1 0.574217
LUM lumican 0.572273
TMPRSS11D transmembrane protease, serine 11D 0.571495
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.569552
CD40 CD40 molecule, TNF receptor superfamily member 5 0.566443
TIMELESS timeless circadian clock 0.566443
NMT1 N-myristoyltransferase 1 0.5645
ADGRE1 adhesion G protein-coupled receptor E1 0.563723
DAXX death-domain associated protein 0.55945
HIST2H2AC histone cluster 2, H2ac 0.559062
HIST2H2AA4 histone cluster 2, H2aa4 0.558674
HIST2H2AA3 histone cluster 2, H2aa3 0.558674
COQ6 coenzyme Q6 monooxygenase 0.553239
HDAC9 histone deacetylase 9 0.553239
PHF12 PHD finger protein 12 0.550522
SPPL3 signal peptide peptidase like 3 0.548583
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.547419
TSPO translocator protein (18kDa) 0.547032
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.545481
IL18 interleukin 18 0.540829
WRB tryptophan rich basic protein 0.53928
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.538506
ALAD aminolevulinate dehydratase 0.536957
IRF1 interferon regulatory factor 1 0.536957
PRRC2A proline-rich coiled-coil 2A 0.529994
NQO2 NAD(P)H dehydrogenase, quinone 2 0.529608
STK35 serine/threonine kinase 35 0.529222
NEK4 NIMA-related kinase 4 0.528835
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.525746
RPS9 ribosomal protein S9 0.52343
OIT3 oncoprotein induced transcript 3 0.520731
FLNA filamin A, alpha 0.518805
AQR aquarius intron-binding spliceosomal factor 0.517265
IDO1 indoleamine 2,3-dioxygenase 1 0.516879
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.516494
GLS2 glutaminase 2 (liver, mitochondrial) 0.516494
CRYZ crystallin, zeta (quinone reductase) 0.513417
TLR5 toll-like receptor 5 0.512264
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 0.510728
ADCY9 adenylate cyclase 9 0.510344
NDC1 NDC1 transmembrane nucleoporin 0.508424
PGK2 phosphoglycerate kinase 2 0.505356
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.501144
NELFE negative elongation factor complex member E 0.500761
TLR6 toll-like receptor 6 0.499997
TCHH trichohyalin 0.499997
FICD FIC domain containing 0.497321
INS insulin 0.496175
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.495029
TLR7 toll-like receptor 7 0.495029
TEAD2 TEA domain family member 2 0.494648
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 0.494648
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.494266
CPZ carboxypeptidase Z 0.493503
SUCLG1 succinate-CoA ligase, alpha subunit 0.491215
RTN3 reticulon 3 0.490454
PDIK1L PDLIM1 interacting kinase 1 like 0.488169
CSN1S1 casein alpha s1 0.487027
BCHE butyrylcholinesterase 0.486646
TTR transthyretin 0.486266
PLAUR plasminogen activator, urokinase receptor 0.483985
RIOK3 RIO kinase 3 0.480945
KIF22 kinesin family member 22 0.477909
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.477151
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.475634
F3 coagulation factor III (thromboplastin, tissue factor) 0.474498
FDPS farnesyl diphosphate synthase 0.471846
THBD thrombomodulin 0.471089
H3F3A H3 histone, family 3A 0.470332
H3F3B H3 histone, family 3B (H3.3B) 0.470332
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 0.468063
BSG basigin (Ok blood group) 0.466928
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.466928
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.465794
LTF lactotransferrin 0.465416
KRT75 keratin 75, type II 0.463905
ACE2 angiotensin I converting enzyme 2 0.462394
CD40LG CD40 ligand 0.462394
DTD1 D-tyrosyl-tRNA deacylase 1 0.458996
PLA2G1B phospholipase A2, group IB (pancreas) 0.457487
EPO erythropoietin 0.455978
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.45447
PCSK6 proprotein convertase subtilisin/kexin type 6 0.453339
HAGH hydroxyacylglutathione hydrolase 0.452962
METTL7A methyltransferase like 7A 0.448064
RIOK2 RIO kinase 2 0.448064
APOL6 apolipoprotein L, 6 0.447687
TLR1 toll-like receptor 1 0.447311
HLA-E major histocompatibility complex, class I, E 0.447311
ETNK1 ethanolamine kinase 1 0.447311
RPL7A ribosomal protein L7a 0.446558
SRCIN1 SRC kinase signaling inhibitor 1 0.445052
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.4443
DPT dermatopontin 0.442418
PGLS 6-phosphogluconolactonase 0.43941
PGM1 phosphoglucomutase 1 0.43753
CCL4 chemokine (C-C motif) ligand 4 0.435275
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 0.434524
PGLYRP1 peptidoglycan recognition protein 1 0.431894
ISPD isoprenoid synthase domain containing 0.431519
CYTH1 cytohesin 1 0.430393
NT5E 5'-nucleotidase, ecto (CD73) 0.42814
GLO1 glyoxalase I 0.42739
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 0.425514
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 0.425139
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.424765
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 0.424014
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.420641
ANPEP alanyl (membrane) aminopeptidase 0.419142
KLHL2 kelch-like family member 2 0.419142
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.418768
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.418019
DNPEP aspartyl aminopeptidase 0.415398
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.413527
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 0.413153
CDK7 cyclin-dependent kinase 7 0.412779
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.412779
GSTM2 glutathione S-transferase mu 2 (muscle) 0.412405
GAGE12F G antigen 12F 0.412405
WAPAL wings apart-like homolog (Drosophila) 0.411283
SARS seryl-tRNA synthetase 0.407919
NKX2-1 NK2 homeobox 1 0.407172
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 0.406051
TPI1 triosephosphate isomerase 1 0.402318
NLRP3 NLR family, pyrin domain containing 3 0.398962
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.398216
CD9 CD9 molecule 0.398216
CD8B CD8b molecule 0.394863
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 0.391141
ATG3 autophagy related 3 0.390397
ATP11A ATPase, class VI, type 11A 0.385565
ECD ecdysoneless homolog (Drosophila) 0.385193
WDFY2 WD repeat and FYVE domain containing 2 0.384079
MDH1 malate dehydrogenase 1, NAD (soluble) 0.381852
RTP1 receptor (chemosensory) transporter protein 1 0.379626
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.378885
F2 coagulation factor II (thrombin) 0.378885
ADH6 alcohol dehydrogenase 6 (class V) 0.376661
NCAM1 neural cell adhesion molecule 1 0.37555
IL12RB1 interleukin 12 receptor, beta 1 0.374068
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.374068
PBK PDZ binding kinase 0.373328
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.372958
EEF1A1P6 eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 0.371847
PDS5B PDS5 cohesin associated factor B 0.371107
IL1RN interleukin 1 receptor antagonist 0.370737
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.369997
GPI glucose-6-phosphate isomerase 0.365932
CD44 CD44 molecule (Indian blood group) 0.364824
FBXO17 F-box protein 17 0.362978
GCH1 GTP cyclohydrolase 1 0.362978
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.361502
LBR lamin B receptor 0.360764
AHCY adenosylhomocysteinase 0.359289
HSF5 heat shock transcription factor family member 5 0.359289
TBX21 T-box 21 0.35892
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.35892
CD1E CD1e molecule 0.357446
LAG3 lymphocyte-activation gene 3 0.357077
ATR ATR serine/threonine kinase 0.357077
MARVELD3 MARVEL domain containing 3 0.355972
TTPA tocopherol (alpha) transfer protein 0.353395
VNN3 vanin 3 0.353395
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.353027
CCL7 chemokine (C-C motif) ligand 7 0.353027
PTMS parathymosin 0.352291
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.351923
FCRL4 Fc receptor-like 4 0.351555
CD38 CD38 molecule 0.350084
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.347144
PRKG1 protein kinase, cGMP-dependent, type I 0.346409
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 0.343473
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 0.342739
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.340906
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.339806
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.338707
TCN2 transcobalamin II 0.337975
CLEC3A C-type lectin domain family 3, member A 0.33651
SYNE2 spectrin repeat containing, nuclear envelope 2 0.335778
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.334681
IL12B interleukin 12B 0.334315
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 0.332852
DLL1 delta-like 1 (Drosophila) 0.331756
CLEC2B C-type lectin domain family 2, member B 0.331756
USP9X ubiquitin specific peptidase 9, X-linked 0.331391
AICDA activation-induced cytidine deaminase 0.33066
METAP2 methionyl aminopeptidase 2 0.328834
CA14 carbonic anhydrase XIV 0.32774
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.327375
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.324823
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 0.324094
IL31RA interleukin 31 receptor A 0.32373
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.32373
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.323002
ZBED9 zinc finger, BED-type containing 9 0.322637
LCT lactase 0.316819
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.316456
PFKM phosphofructokinase, muscle 0.316456
ADCY2 adenylate cyclase 2 (brain) 0.316092
MBL2 mannose-binding lectin (protein C) 2, soluble 0.315729
CREM cAMP responsive element modulator 0.31464
CNOT7 CCR4-NOT transcription complex, subunit 7 0.31464
CCR2 chemokine (C-C motif) receptor 2 0.313915
C3 complement component 3 0.312827
SCN2A sodium channel, voltage gated, type II alpha subunit 0.311739
ARRB2 arrestin, beta 2 0.311739
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.311377
SPTB spectrin, beta, erythrocytic 0.311014
CLEC10A C-type lectin domain family 10, member A 0.309204
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 0.30848
RGMB repulsive guidance molecule family member b 0.308118
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 0.307395
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.306672
CXCL8 chemokine (C-X-C motif) ligand 8 0.306672
RTP2 receptor (chemosensory) transporter protein 2 0.30342
CFD complement factor D (adipsin) 0.302698
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.299812
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 0.297291
CD163 CD163 molecule 0.296931
CADM1 cell adhesion molecule 1 0.296211
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.293694
HCAR1 hydroxycarboxylic acid receptor 1 0.291898
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.29118
PFN2 profilin 2 0.290821
TRAC T cell receptor alpha constant 0.290462
AK2 adenylate kinase 2 0.289744
GNPDA1 glucosamine-6-phosphate deaminase 1 0.28831
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.287593
MMP9 matrix metallopeptidase 9 0.286877
SPON1 spondin 1, extracellular matrix protein 0.284728
FRY furry homolog (Drosophila) 0.284728
MRC2 mannose receptor, C type 2 0.284371
SIRT2 sirtuin 2 0.283297
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 0.282582
MSH2 mutS homolog 2 0.280439
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 0.279367
NPS neuropeptide S 0.279367
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.279367
FASLG Fas ligand (TNF superfamily, member 6) 0.279367
ACP1 acid phosphatase 1, soluble 0.279011
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 0.279011
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 0.27794
TRIM5 tripartite motif containing 5 0.277584
PLA2G15 phospholipase A2, group XV 0.277584
COCH cochlin 0.277227
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 0.27687
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 0.276514
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 0.276158
ELANE elastase, neutrophil expressed 0.274732
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 0.274732
LY96 lymphocyte antigen 96 0.272953
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.272953
ORC5 origin recognition complex, subunit 5 0.27153
LZTS1 leucine zipper, putative tumor suppressor 1 0.271174
ANXA7 annexin A7 0.270464
MMP10 matrix metallopeptidase 10 0.270464
CHKA choline kinase alpha 0.270108
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 0.269753
FAM131C family with sequence similarity 131, member C 0.269043
CARD17 caspase recruitment domain family, member 17 0.267267
CA5A carbonic anhydrase VA, mitochondrial 0.266558
GSN gelsolin 0.265849
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.26514
CTSL cathepsin L 0.264785
LIN7A lin-7 homolog A (C. elegans) 0.264785
SOCS2 suppressor of cytokine signaling 2 0.264431
FKBP1A FK506 binding protein 1A, 12kDa 0.264431
OR13F1 olfactory receptor, family 13, subfamily F, member 1 0.264077
RCAN1 regulator of calcineurin 1 0.263722
PF4 platelet factor 4 0.263014
GPR182 G protein-coupled receptor 182 0.26266
BUB3 BUB3 mitotic checkpoint protein 0.26266
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.261952
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.261599
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 0.260538
ZNF296 zinc finger protein 296 0.25983
SEMG1 semenogelin I 0.25983
CCL5 chemokine (C-C motif) ligand 5 0.25877
COX6CP4 cytochrome c oxidase subunit VIc pseudogene 4 0.257711
IFNA1 interferon, alpha 1 0.257005
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 0.257005
SP8 Sp8 transcription factor 0.256299
MB myoglobin 0.255241
LY75 lymphocyte antigen 75 0.255241
SPATA19 spermatogenesis associated 19 0.255241
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.254888
MKX mohawk homeobox 0.254888
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 0.254536
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.254536
C3AR1 complement component 3a receptor 1 0.253831
PNN pinin, desmosome associated protein 0.253127
SPTA1 spectrin, alpha, erythrocytic 1 0.250663
ESD esterase D 0.24996
IRAK4 interleukin-1 receptor-associated kinase 4 0.248203
ADSS adenylosuccinate synthase 0.246098
LIPT1 lipoyltransferase 1 0.245046
DSCAM Down syndrome cell adhesion molecule 0.241546
KIF5B kinesin family member 5B 0.241196
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.239799
CTSW cathepsin W 0.239101
HLA-DMA major histocompatibility complex, class II, DM alpha 0.238403
TXNRD3 thioredoxin reductase 3 0.237009
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 0.235268
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.23492
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.234573
CTRL chymotrypsin-like 0.234225
THY1 Thy-1 cell surface antigen 0.231795
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.231448
PDCD1 programmed cell death 1 0.231102
CTSB cathepsin B 0.231102
IL10RB interleukin 10 receptor, beta 0.230755
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.230409
SELT selenoprotein T 0.228679
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.228679
LST1 leukocyte specific transcript 1 0.228679
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.227988
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.226607
THOP1 thimet oligopeptidase 1 0.225573
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.224884
PPA2 pyrophosphatase (inorganic) 2 0.223509
LIG3 ligase III, DNA, ATP-dependent 0.223509
OR2B2 olfactory receptor, family 2, subfamily B, member 2 0.222479
CD19 CD19 molecule 0.220081
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.21974
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) 0.218715
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.216332
PGK1 phosphoglycerate kinase 1 0.213959
SPAG7 sperm associated antigen 7 0.213959
AGPS alkylglycerone phosphate synthase 0.213959
SRPX2 sushi-repeat containing protein, X-linked 2 0.213959
CAST calpastatin 0.212945
TUBA1A tubulin, alpha 1a 0.212608
FPGS folylpolyglutamate synthase 0.212608
DNAH8 dynein, axonemal, heavy chain 8 0.212608
SH2B3 SH2B adaptor protein 3 0.210925
IL17RE interleukin 17 receptor E 0.210925
HK1 hexokinase 1 0.210589
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.209583
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.209248
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.206913
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 0.206248
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 0.206248
SLC2A4RG SLC2A4 regulator 0.206248
IL5 interleukin 5 0.204593
HTN1 histatin 1 0.203604
TOP1 topoisomerase (DNA) I 0.202946
SPPL2B signal peptide peptidase like 2B 0.202618
HIST1H4E histone cluster 1, H4e 0.201962
HIST2H4B histone cluster 2, H4b 0.201962
HIST1H4A histone cluster 1, H4a 0.201962
HIST1H4D histone cluster 1, H4d 0.201962
HIST1H4F histone cluster 1, H4f 0.201962
HIST1H4K histone cluster 1, H4k 0.201962
HIST1H4I histone cluster 1, H4i 0.201962
HIST1H4J histone cluster 1, H4j 0.201962
HIST1H4C histone cluster 1, H4c 0.201962
HIST1H4B histone cluster 1, H4b 0.201962
HIST1H4H histone cluster 1, H4h 0.201962
HIST2H4A histone cluster 2, H4a 0.201308
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 0.201308
HIST4H4 histone cluster 4, H4 0.199681
HIST1H4L histone cluster 1, H4l 0.199681
IL2RA interleukin 2 receptor, alpha 0.198386
ATP13A1 ATPase type 13A1 0.198386
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 0.197742
AK3 adenylate kinase 3 0.197742
SRXN1 sulfiredoxin 1 0.194548
CCR7 chemokine (C-C motif) receptor 7 0.194548
PERP PERP, TP53 apoptosis effector 0.194232
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.193915
TXN thioredoxin 0.192971
FASN fatty acid synthase 0.192031
KRT39 keratin 39, type I 0.191719
DNM2 dynamin 2 0.191097
LYZ lysozyme 0.190476
RBM4 RNA binding motif protein 4 0.190168
CXCL11 chemokine (C-X-C motif) ligand 11 0.188938
KRT84 keratin 84, type II 0.185612
CD59 CD59 molecule, complement regulatory protein 0.185313
HRH2 histamine receptor H2 0.184128
MAP1S microtubule-associated protein 1S 0.184128
CCL3L1 chemokine (C-C motif) ligand 3-like 1 0.184128
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.183248
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.182957
HBZ hemoglobin, zeta 0.182375
SAMD11 sterile alpha motif domain containing 11 0.181798
TREM1 triggering receptor expressed on myeloid cells 1 0.180937
MEGF6 multiple EGF-like-domains 6 0.180367
ACO2 aconitase 2, mitochondrial 0.180084
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.17952
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.177851
IL17RD interleukin 17 receptor D 0.177576
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.177301
CALR calreticulin 0.176757
GSTM3 glutathione S-transferase mu 3 (brain) 0.176485
LDB3 LIM domain binding 3 0.176485
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.176485
PRODH proline dehydrogenase (oxidase) 1 0.176215
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.175679
SEC13 SEC13 homolog (S. cerevisiae) 0.174617
RPS29 ribosomal protein S29 0.174354
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.174354
GAGE12I G antigen 12I 0.173571
CAPN7 calpain 7 0.173314
MAEA macrophage erythroblast attacher 0.172544
TES testin LIM domain protein 0.172291
C6ORF25 chromosome 6 open reading frame 25 0.171286
HRC histidine rich calcium binding protein 0.169812
KLHL17 kelch-like family member 17 0.168148
EIF4E eukaryotic translation initiation factor 4E 0.168148
BTLA B and T lymphocyte associated 0.167915
EARS2 glutamyl-tRNA synthetase 2, mitochondrial 0.167682
C1QBP complement component 1, q subcomponent binding protein 0.167452
SYK spleen tyrosine kinase 0.166995
B2M beta-2-microglobulin 0.166544
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.166319
GSS glutathione synthetase 0.165874
GLS glutaminase 0.165655
METTL13 methyltransferase like 13 0.165435
PROS1 protein S (alpha) 0.165001
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.163938
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 0.163523
FEN1 flap structure-specific endonuclease 1 0.162505
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.162306
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.160948
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.160761
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.160574
MAGEB1 melanoma antigen family B1 0.160387
IRF3 interferon regulatory factor 3 0.160021
PAH phenylalanine hydroxylase 0.159838
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.15948
CXCL2 chemokine (C-X-C motif) ligand 2 0.159124
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.158434
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 0.158434
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.158097
ZNF347 zinc finger protein 347 0.157929
KIF1B kinesin family member 1B 0.144998
ARF5 ADP-ribosylation factor 5 0.140899
XK X-linked Kx blood group 0.133904
TJP1 tight junction protein 1 0.132786
HAND2 heart and neural crest derivatives expressed 2 0.132347
FLOT2 flotillin 2 0.130952
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.130003
CEMP1 cementum protein 1 0.127545
MID1 midline 1 0.126813
ACMSD aminocarboxymuconate semialdehyde decarboxylase 0.125986
PGM2 phosphoglucomutase 2 0.125952
CLEC4A C-type lectin domain family 4, member A 0.125935
PGAP3 post-GPI attachment to proteins 3 0.125149
LVRN laeverin 0.124741
RPE ribulose-5-phosphate-3-epimerase 0.124303
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 0.124225
HRH4 histamine receptor H4 0.123672
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.122573
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.122377
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.122138
SEPT9 septin 9 0.120442
GPAA1 glycosylphosphatidylinositol anchor attachment 1 0.120058
B3GAT2 beta-1,3-glucuronyltransferase 2 0.119861
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.119861
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.119314
CAPN2 calpain 2, (m/II) large subunit 0.117002
C5AR2 complement component 5a receptor 2 0.117002
CAV2 caveolin 2 0.116945
TLR8 toll-like receptor 8 0.116691
PTGDR prostaglandin D2 receptor (DP) 0.116635
PEX2 peroxisomal biogenesis factor 2 0.115537
HMGB1 high mobility group box 1 0.115537
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.115418
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.114817
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.114727
CLEC11A C-type lectin domain family 11, member A 0.114108
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 0.113953
HDC histidine decarboxylase 0.113543
PEPD peptidase D 0.113415
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.112903
LGALS2 lectin, galactoside-binding, soluble, 2 0.112343
TIMD4 T-cell immunoglobulin and mucin domain containing 4 0.111981
ARG1 arginase 1 0.110053
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 0.109981
SAA2 serum amyloid A2 0.109945
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.108825
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 0.10805
CD28 CD28 molecule 0.10805
TLK2 tousled-like kinase 2 0.10786
CD83 CD83 molecule 0.107367
OCLN occludin 0.106754
ANOS1 anosmin 1 0.105616
NBPF8 neuroblastoma breakpoint family, member 8 0.105496
MAPK11 mitogen-activated protein kinase 11 0.105416
THBS1 thrombospondin 1 0.104976
WRAP73 WD repeat containing, antisense to TP73 0.104857
STIL SCL/TAL1 interrupting locus 0.104817
NRP1 neuropilin 1 0.104735
GML glycosylphosphatidylinositol anchored molecule like 0.104366
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.103955
CDKN2A cyclin-dependent kinase inhibitor 2A 0.103585
MOGS mannosyl-oligosaccharide glucosidase 0.103501
TFDP3 transcription factor Dp family, member 3 0.103206
LMAN1 lectin, mannose-binding, 1 0.102702
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.102492
CARD9 caspase recruitment domain family, member 9 0.102319
ARG2 arginase 2 0.102233
SEBOX SEBOX homeobox 0.102233
IFI16 interferon, gamma-inducible protein 16 0.102233
IRF8 interferon regulatory factor 8 0.102104
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.101888
SATB2 SATB homeobox 2 0.101716
CD1B CD1b molecule 0.101716
CAV3 caveolin 3 0.101501
MYO5A myosin VA (heavy chain 12, myoxin) 0.101329
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.101286
CTRC chymotrypsin C (caldecrin) 0.101065
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.100801
CXCR2 chemokine (C-X-C motif) receptor 2 0.100668
MMP3 matrix metallopeptidase 3 0.100095
RD3 retinal degeneration 3 0.100006
PRDX5 peroxiredoxin 5 0.099735
HPSE2 heparanase 2 (inactive) 0.099735
FABP3 fatty acid binding protein 3, muscle and heart 0.09951
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.099149
GSTO1 glutathione S-transferase omega 1 0.098969
ANXA1 annexin A1 0.098969
DCT dopachrome tautomerase 0.09865
CNR2 cannabinoid receptor 2 (macrophage) 0.098465
CLU clusterin 0.098465
TMEM51 transmembrane protein 51 0.098419
CP ceruloplasmin (ferroxidase) 0.098373
ASL argininosuccinate lyase 0.098373
VCL vinculin 0.098097
TNNT1 troponin T type 1 (skeletal, slow) 0.097309
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.096791
RAG2 recombination activating gene 2 0.096509
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.096035
NADK NAD kinase 0.095939
NCF1 neutrophil cytosolic factor 1 0.09589