main axon Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The main axonal trunk, as opposed to the collaterals. (Gene Ontology, GO_0044304)
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Genes

252 proteins co-occuring with the main axon cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 2.53101
CNTNAP1 contactin associated protein 1 2.43676
NFASC neurofascin 2.39187
SPTBN4 spectrin, beta, non-erythrocytic 4 1.87796
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 1.86831
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 1.82931
SCN8A sodium channel, voltage gated, type VIII alpha subunit 1.79442
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.7832
PVALB parvalbumin 1.53557
CNTN2 contactin 2 (axonal) 1.4938
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 1.46043
MAG myelin associated glycoprotein 1.43951
NRCAM neuronal cell adhesion molecule 1.34938
GLDN gliomedin 1.326
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 1.31196
ANK1 ankyrin 1, erythrocytic 1.20035
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 1.1516
ANK2 ankyrin 2, neuronal 1.13063
ACHE acetylcholinesterase (Yt blood group) 1.09136
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 1.06549
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 1.0413
SCN2A sodium channel, voltage gated, type II alpha subunit 0.971297
FGF14 fibroblast growth factor 14 0.955439
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.944482
CALB1 calbindin 1, 28kDa 0.929833
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.923728
UGT8 UDP glycosyltransferase 8 0.90832
DNAH8 dynein, axonemal, heavy chain 8 0.905996
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.903673
NAV1 neuron navigator 1 0.89672
MBP myelin basic protein 0.852961
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 0.828171
TNR tenascin R 0.818075
SCN10A sodium channel, voltage gated, type X alpha subunit 0.817158
CCK cholecystokinin 0.813028
GAL3ST1 galactose-3-O-sulfotransferase 1 0.801104
ADGRG2 adhesion G protein-coupled receptor G2 0.800187
TH tyrosine hydroxylase 0.797436
TAC1 tachykinin, precursor 1 0.78004
CALB2 calbindin 2 0.769539
AACS acetoacetyl-CoA synthetase 0.766804
CNTNAP2 contactin associated protein-like 2 0.761797
CHAT choline O-acetyltransferase 0.75453
RNASE10 ribonuclease, RNase A family, 10 (non-active) 0.750452
GPHN gephyrin 0.731524
SYP synaptophysin 0.729284
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 0.705714
CST8 cystatin 8 (cystatin-related epididymal specific) 0.705273
SCN3A sodium channel, voltage gated, type III alpha subunit 0.666394
L1CAM L1 cell adhesion molecule 0.665962
CELF4 CUGBP, Elav-like family member 4 0.664664
CLU clusterin 0.662935
MPZ myelin protein zero 0.662503
ETV4 ets variant 4 0.662503
HPGDS hematopoietic prostaglandin D synthase 0.656895
CALCA calcitonin-related polypeptide alpha 0.647433
NPY neuropeptide Y 0.638434
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.63715
EPB41 erythrocyte membrane protein band 4.1 0.635868
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.632878
BCAN brevican 0.629465
GJB1 gap junction protein, beta 1, 32kDa 0.629039
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.620104
OMG oligodendrocyte myelin glycoprotein 0.620104
PRX periaxin 0.605284
RTN4R reticulon 4 receptor 0.596014
FGF12 fibroblast growth factor 12 0.577581
CST11 cystatin 11 0.574244
SCN1A sodium channel, voltage gated, type I alpha subunit 0.560528
SCHIP1 schwannomin interacting protein 1 0.529618
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.524704
GPM6A glycoprotein M6A 0.523885
NPS neuropeptide S 0.519389
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 0.51164
ETV5 ets variant 5 0.509197
GJC2 gap junction protein, gamma 2, 47kDa 0.50879
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.504318
CLDN19 claudin 19 0.502288
AQP9 aquaporin 9 0.493775
NLGN2 neuroligin 2 0.492157
CPNE6 copine VI (neuronal) 0.490944
SCN1B sodium channel, voltage gated, type I beta subunit 0.487711
DLG4 discs, large homolog 4 (Drosophila) 0.485289
MAP1B microtubule-associated protein 1B 0.484886
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.484483
SST somatostatin 0.484483
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.481258
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 0.48005
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.474018
PMP22 peripheral myelin protein 22 0.468802
TPRKB TP53RK binding protein 0.466799
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.459203
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.456012
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.454418
SCN2B sodium channel, voltage gated, type II beta subunit 0.454019
SORBS3 sorbin and SH3 domain containing 3 0.449245
NTN1 netrin 1 0.449245
PHTF1 putative homeodomain transcription factor 1 0.445275
NCAM1 neural cell adhesion molecule 1 0.443292
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 0.43696
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.436565
TNC tenascin C 0.436565
ESR2 estrogen receptor 2 (ER beta) 0.434985
OPALIN oligodendrocytic myelin paranodal and inner loop protein 0.432618
NGF nerve growth factor (beta polypeptide) 0.430647
CST4 cystatin S 0.429859
CLDN10 claudin 10 0.428678
CADM3 cell adhesion molecule 3 0.425924
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 0.425531
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 0.420428
DCP1B decapping mRNA 1B 0.419252
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.41886
NRG1 neuregulin 1 0.417294
BCHE butyrylcholinesterase 0.411039
DEFB126 defensin, beta 126 0.411039
NTN3 netrin 3 0.410649
TBC1D24 TBC1 domain family, member 24 0.407919
ADAM7 ADAM metallopeptidase domain 7 0.399363
CA2 carbonic anhydrase II 0.394323
TMEM245 transmembrane protein 245 0.394323
DOLK dolichol kinase 0.393936
WDFY1 WD repeat and FYVE domain containing 1 0.385051
ZNF91 zinc finger protein 91 0.384665
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.38428
SYNPO synaptopodin 0.381969
LCN8 lipocalin 8 0.375434
MRRF mitochondrial ribosome recycling factor 0.371982
MFGE8 milk fat globule-EGF factor 8 protein 0.363567
AR androgen receptor 0.361659
CLTC clathrin, heavy chain (Hc) 0.360515
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.352522
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.352142
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.351762
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.351762
CADM2 cell adhesion molecule 2 0.351762
CDK20 cyclin-dependent kinase 20 0.350243
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.346829
ZIC4 Zic family member 4 0.342285
ICAM5 intercellular adhesion molecule 5, telencephalin 0.338128
ERBB3 erb-b2 receptor tyrosine kinase 3 0.337373
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.332472
CLDN11 claudin 11 0.331719
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 0.330966
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 0.328332
RTN4 reticulon 4 0.327956
ERMN ermin, ERM-like protein 0.327581
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.327581
POU3F1 POU class 3 homeobox 1 0.326453
MIR19A microRNA 19a 0.325702
MTMR2 myotubularin related protein 2 0.322325
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.320077
PLA2G1B phospholipase A2, group IB (pancreas) 0.315212
KIF5C kinesin family member 5C 0.311478
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.310358
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.309986
LGI1 leucine-rich, glioma inactivated 1 0.30924
ESR1 estrogen receptor 1 0.308494
JAM3 junctional adhesion molecule 3 0.304399
CNTN4 contactin 4 0.303283
GALC galactosylceramidase 0.302912
FGF1 fibroblast growth factor 1 (acidic) 0.302168
FOXD3 forkhead box D3 0.29623
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.292897
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase 0.291417
RELN reelin 0.290678
CADM4 cell adhesion molecule 4 0.289938
ACPP acid phosphatase, prostate 0.287721
GAP43 growth associated protein 43 0.287352
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.286983
DRP2 dystrophin related protein 2 0.284769
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.278509
ATP11A ATPase, class VI, type 11A 0.277774
DACT2 dishevelled-binding antagonist of beta-catenin 2 0.276304
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.275202
NT5E 5'-nucleotidase, ecto (CD73) 0.274835
MAPT microtubule-associated protein tau 0.274101
FGF11 fibroblast growth factor 11 0.272633
ALPPL2 alkaline phosphatase, placental-like 2 0.271533
HRASLS5 HRAS-like suppressor family, member 5 0.271167
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 0.271167
ALPP alkaline phosphatase, placental 0.2708
ALPL alkaline phosphatase, liver/bone/kidney 0.2708
CKAP4 cytoskeleton-associated protein 4 0.264946
SERBP1 SERPINE1 mRNA binding protein 1 0.264581
HEXB hexosaminidase B (beta polypeptide) 0.263485
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.26239
PATE1 prostate and testis expressed 1 0.255107
HDC histidine decarboxylase 0.253653
MIR27B microRNA 27b 0.253653
GDA guanine deaminase 0.250026
SLCO4C1 solute carrier organic anion transporter family, member 4C1 0.249664
SYN1 synapsin I 0.24894
PROM2 prominin 2 0.248216
SHBG sex hormone-binding globulin 0.247492
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.243879
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.243519
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.240276
NTNG2 netrin G2 0.237042
SBF2 SET binding factor 2 0.234533
VCAN versican 0.234533
CERKL ceramide kinase-like 0.234533
CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.234174
NVL nuclear VCP-like 0.233817
STC2 stanniocalcin 2 0.227397
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.227041
FGF17 fibroblast growth factor 17 0.226331
FGF2 fibroblast growth factor 2 (basic) 0.223497
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.221378
AASS aminoadipate-semialdehyde synthase 0.217861
RICTOR RPTOR independent companion of MTOR, complex 2 0.21716
NGFR nerve growth factor receptor 0.215761
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 0.213669
NKX6-2 NK6 homeobox 2 0.208825
FGF13 fibroblast growth factor 13 0.201672
DOCK7 dedicator of cytokinesis 7 0.200999
GJC3 gap junction protein, gamma 3, 30.2kDa 0.200663
CRIP1 cysteine-rich protein 1 (intestinal) 0.200328
DUSP6 dual specificity phosphatase 6 0.199659
NCAN neurocan 0.199659
CRH corticotropin releasing hormone 0.19601
GRIK2 glutamate receptor, ionotropic, kainate 2 0.195681
SPTBN1 spectrin, beta, non-erythrocytic 1 0.191135
CTSD cathepsin D 0.189539
BIN1 bridging integrator 1 0.18796
MAP2 microtubule-associated protein 2 0.187646
EZR ezrin 0.182723
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.180339
MFRP membrane frizzled-related protein 0.179167
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 0.17687
HEXA hexosaminidase A (alpha polypeptide) 0.176587
NF2 neurofibromin 2 (merlin) 0.174087
ETV1 ets variant 1 0.173543
FAM155B family with sequence similarity 155, member B 0.173003
DNM2 dynamin 2 0.173003
NCALD neurocalcin delta 0.171673
AQP4 aquaporin 4 0.17141
MOG myelin oligodendrocyte glycoprotein 0.170114
NAV2 neuron navigator 2 0.168847
TPH1 tryptophan hydroxylase 1 0.168598
SOD1 superoxide dismutase 1, soluble 0.167611
CCNF cyclin F 0.167366
LINGO1 leucine rich repeat and Ig domain containing 1 0.167125
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.164542
CA1 carbonic anhydrase I 0.164542
PANX3 pannexin 3 0.163641
AVP arginine vasopressin 0.162546
CD1C CD1c molecule 0.161068
SCN4A sodium channel, voltage gated, type IV alpha subunit 0.161068
SYT2 synaptotagmin II 0.158502
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 0.158315
FOXA3 forkhead box A3 0.157943
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.157218