macular degeneration Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye; symptoms include vision loss. (Human Disease Ontology, DOID_4448)
Similar Terms
Downloads & Tools

Genes

506 genes co-occuring with the disease macular degeneration in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CFH complement factor H 3.03445
HTRA1 HtrA serine peptidase 1 2.50177
VEGFA vascular endothelial growth factor A 2.49857
BEST1 bestrophin 1 2.46844
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.43668
CFB complement factor B 2.09759
ELOVL4 ELOVL fatty acid elongase 4 2.02341
C2 complement component 2 1.77044
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 1.70588
HMCN1 hemicentin 1 1.65745
TIMP3 TIMP metallopeptidase inhibitor 3 1.65295
CFHR3 complement factor H-related 3 1.64846
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 1.64532
CFHR1 complement factor H-related 1 1.58091
RPE65 retinal pigment epithelium-specific protein 65kDa 1.57556
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.568
RHO rhodopsin 1.56711
C3 complement component 3 1.49438
RP1L1 retinitis pigmentosa 1-like 1 1.4913
RDH8 retinol dehydrogenase 8 (all-trans) 1.29615
RLBP1 retinaldehyde binding protein 1 1.27955
PLAT plasminogen activator, tissue 1.27955
CFHR4 complement factor H-related 4 1.27868
PRPH2 peripherin 2 (retinal degeneration, slow) 1.26647
RS1 retinoschisin 1 1.25645
LIPC lipase, hepatic 1.25602
FLT1 fms-related tyrosine kinase 1 1.2356
CFI complement factor I 1.22388
RAP2A RAP2A, member of RAS oncogene family 1.22302
BEST2 bestrophin 2 1.19661
APOE apolipoprotein E 1.17464
CCL2 chemokine (C-C motif) ligand 2 1.14942
ATXN7 ataxin 7 1.12656
COL18A1 collagen, type XVIII, alpha 1 1.11645
VEGFB vascular endothelial growth factor B 1.11645
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 1.11561
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.10973
HEPH hephaestin 1.10931
FBLN5 fibulin 5 1.09671
AGBL4 ATP/GTP binding protein-like 4 1.08495
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 1.07992
CD46 CD46 molecule, complement regulatory protein 1.0648
BEST4 bestrophin 4 1.06312
NOA1 nitric oxide associated 1 1.06102
SEBOX SEBOX homeobox 1.0606
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.05934
CFHR5 complement factor H-related 5 1.0484
CFHR2 complement factor H-related 2 1.04504
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.04125
KDR kinase insert domain receptor 0.993596
CCR2 chemokine (C-C motif) receptor 2 0.987271
TLR3 toll-like receptor 3 0.980531
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 0.949936
C1QTNF5 C1q and tumor necrosis factor related protein 5 0.943274
FGF2 fibroblast growth factor 2 (basic) 0.941196
RING1 ring finger protein 1 0.938289
PGF placental growth factor 0.934141
SOD2 superoxide dismutase 2, mitochondrial 0.9238
NELFE negative elongation factor complex member E 0.922149
MMP2 matrix metallopeptidase 2 0.909787
ROM1 retinal outer segment membrane protein 1 0.897461
CRX cone-rod homeobox 0.889258
CRP C-reactive protein, pentraxin-related 0.872462
VLDLR very low density lipoprotein receptor 0.867959
IL17RC interleukin 17 receptor C 0.849945
TRAPPC6B trafficking protein particle complex 6B 0.837246
F13B coagulation factor XIII, B polypeptide 0.832738
IMPG1 interphotoreceptor matrix proteoglycan 1 0.828229
COL8A1 collagen, type VIII, alpha 1 0.827409
CP ceruloplasmin (ferroxidase) 0.81018
CD59 CD59 molecule, complement regulatory protein 0.806898
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.785574
TNMD tenomodulin 0.783526
C5AR1 complement component 5a receptor 1 0.775341
MARS methionyl-tRNA synthetase 0.77207
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.770435
MSRB2 methionine sulfoxide reductase B2 0.751271
TDRP testis development related protein 0.739488
MMP9 matrix metallopeptidase 9 0.734217
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.732596
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.730166
AIF1 allograft inflammatory factor 1 0.722482
NRP1 neuropilin 1 0.720865
HMOX1 heme oxygenase 1 0.715215
DIAPH2 diaphanous-related formin 2 0.70434
KRT18 keratin 18, type I 0.70434
OPN4 opsin 4 0.698715
TJP1 tight junction protein 1 0.697911
FN1 fibronectin 1 0.692296
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.663975
NLRP3 NLR family, pyrin domain containing 3 0.654067
RIMS1 regulating synaptic membrane exocytosis 1 0.652089
C3AR1 complement component 3a receptor 1 0.652089
ELANE elastase, neutrophil expressed 0.649323
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.641433
TTC33 tetratricopeptide repeat domain 33 0.641039
ELN elastin 0.637102
RNPC3 RNA-binding region (RNP1, RRM) containing 3 0.636708
ICAM1 intercellular adhesion molecule 1 0.635921
CLDN19 claudin 19 0.632384
FSCN2 fascin actin-bundling protein 2, retinal 0.624927
CCR3 chemokine (C-C motif) receptor 3 0.624143
FTMT ferritin mitochondrial 0.622575
SCARB1 scavenger receptor class B, member 1 0.620226
FGF1 fibroblast growth factor 1 (acidic) 0.613574
OCLN occludin 0.608494
CNTF ciliary neurotrophic factor 0.607714
ERP29 endoplasmic reticulum protein 29 0.60264
MFRP membrane frizzled-related protein 0.60225
PAM peptidylglycine alpha-amidating monooxygenase 0.597181
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.596792
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.595233
TSPO translocator protein (18kDa) 0.591337
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 0.586276
ACER2 alkaline ceramidase 2 0.575772
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 0.575772
NRL neural retina leucine zipper 0.572662
CAT catalase 0.570718
PRIMPOL primase and polymerase (DNA-directed) 0.570329
PLA2G12A phospholipase A2, group XIIA 0.569163
PON1 paraoxonase 1 0.561392
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.557509
STARD3 StAR-related lipid transfer (START) domain containing 3 0.554791
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 0.554403
CETP cholesteryl ester transfer protein, plasma 0.552851
GPX1 glutathione peroxidase 1 0.549747
GSG1L GSG1-like 0.549359
BCO2 beta-carotene oxygenase 2 0.548971
B3GALTL beta 1,3-galactosyltransferase-like 0.533861
FEN1 flap structure-specific endonuclease 1 0.533088
PPP3R2 protein phosphatase 3, regulatory subunit B, beta 0.529222
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.528835
MSRA methionine sulfoxide reductase A 0.526518
CTSD cathepsin D 0.52343
AMD1 adenosylmethionine decarboxylase 1 0.52343
MITF microphthalmia-associated transcription factor 0.515725
CST3 cystatin C 0.514956
SLC39A2 solute carrier family 39 (zinc transporter), member 2 0.513802
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.511496
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 0.505356
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 0.499231
FADS1 fatty acid desaturase 1 0.498467
SYT7 synaptotagmin VII 0.498085
CARD17 caspase recruitment domain family, member 17 0.496175
PILRA paired immunoglobin-like type 2 receptor alpha 0.495411
LOXL1 lysyl oxidase-like 1 0.490454
TXN thioredoxin 0.485505
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.483224
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 0.482844
CD68 CD68 molecule 0.480566
TIMP1 TIMP metallopeptidase inhibitor 1 0.478289
KEAP1 kelch-like ECH-associated protein 1 0.476772
FZD4 frizzled class receptor 4 0.476393
BEST3 bestrophin 3 0.472982
OPTC opticin 0.472604
CD34 CD34 molecule 0.472225
PLG plasminogen 0.470711
LPPR4 lipid phosphate phosphatase-related protein type 4 0.467306
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.466928
VEGFC vascular endothelial growth factor C 0.465038
FASLG Fas ligand (TNF superfamily, member 6) 0.463149
SRSF5 serine/arginine-rich splicing factor 5 0.461261
CFP complement factor properdin 0.460883
PAPD4 PAP associated domain containing 4 0.458241
CNGB3 cyclic nucleotide gated channel beta 3 0.457864
DICER1 dicer 1, ribonuclease type III 0.457487
TF transferrin 0.455224
GSTP1 glutathione S-transferase pi 1 0.45447
SCAPER S-phase cyclin A-associated protein in the ER 0.452962
GPX4 glutathione peroxidase 4 0.452962
CBX6 chromobox homolog 6 0.451078
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 0.449947
CTGF connective tissue growth factor 0.444676
VWF von Willebrand factor 0.4443
GLB1 galactosidase, beta 1 0.443923
CXCL12 chemokine (C-X-C motif) ligand 12 0.442795
RPGR retinitis pigmentosa GTPase regulator 0.441666
ANG angiogenin, ribonuclease, RNase A family, 5 0.434524
BMP8B bone morphogenetic protein 8b 0.433397
NGLY1 N-glycanase 1 0.429642
FKBPL FK506 binding protein like 0.42814
CLUL1 clusterin-like 1 (retinal) 0.42739
SIRT1 sirtuin 1 0.42589
RHOJ ras homolog family member J 0.42589
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.42289
NFE2L2 nuclear factor, erythroid 2-like 2 0.422515
GPX5 glutathione peroxidase 5 0.421765
TIMP2 TIMP metallopeptidase inhibitor 2 0.419517
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 0.418394
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.418019
PRL prolactin 0.415398
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.413527
RCVRN recoverin 0.412405
APOB apolipoprotein B 0.411657
TLR4 toll-like receptor 4 0.410161
THEMIS thymocyte selection associated 0.408292
COLEC11 collectin sub-family member 11 0.407919
FTH1 ferritin, heavy polypeptide 1 0.407545
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.407545
ARR3 arrestin 3, retinal (X-arrestin) 0.398962
TNF tumor necrosis factor 0.397843
HSPA4 heat shock 70kDa protein 4 0.39598
AOC3 amine oxidase, copper containing 3 0.392629
AHR aryl hydrocarbon receptor 0.392257
OSBP2 oxysterol binding protein 2 0.390769
BCO1 beta-carotene oxygenase 1 0.388538
IMPG2 interphotoreceptor matrix proteoglycan 2 0.388538
PLA2G12B phospholipase A2, group XIIB 0.385193
THBS1 thrombospondin 1 0.38111
PITPNM3 PITPNM family member 3 0.377773
GPR75 G protein-coupled receptor 75 0.37629
CRYAB crystallin, alpha B 0.37629
LAMB4 laminin, beta 4 0.369997
ALB albumin 0.369258
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.368149
TP53INP1 tumor protein p53 inducible nuclear protein 1 0.366301
MME membrane metallo-endopeptidase 0.365562
ANXA5 annexin A5 0.36187
MMP3 matrix metallopeptidase 3 0.361502
GSTA3 glutathione S-transferase alpha 3 0.361133
GSTA2 glutathione S-transferase alpha 2 0.360026
GSTA4 glutathione S-transferase alpha 4 0.35892
CFD complement factor D (adipsin) 0.358183
ZCWPW1 zinc finger, CW type with PWWP domain 1 0.355235
FMOD fibromodulin 0.354131
GSTA1 glutathione S-transferase alpha 1 0.353027
GCLC glutamate-cysteine ligase, catalytic subunit 0.352659
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.350452
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 0.350452
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.348614
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.347511
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 0.345675
DHDH dihydrodiol dehydrogenase (dimeric) 0.344941
FTL ferritin, light polypeptide 0.344207
XPOT exportin, tRNA 0.34384
MGST1 microsomal glutathione S-transferase 1 0.343473
ANGPT1 angiopoietin 1 0.343106
RBM39 RNA binding motif protein 39 0.340906
SARM1 sterile alpha and TIR motif containing 1 0.340539
CAPZB capping protein (actin filament) muscle Z-line, beta 0.338707
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 0.337608
DSCR8 Down syndrome critical region 8 0.337608
BDH2 3-hydroxybutyrate dehydrogenase, type 2 0.336876
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.333218
KCTD5 potassium channel tetramerization domain containing 5 0.331756
PROM1 prominin 1 0.325187
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.32373
ANGPTL7 angiopoietin-like 7 0.318272
GDF6 growth differentiation factor 6 0.315729
OLFM3 olfactomedin 3 0.31464
IGF1 insulin-like growth factor 1 (somatomedin C) 0.313915
SST somatostatin 0.313552
FLT4 fms-related tyrosine kinase 4 0.313189
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.311377
SYN3 synapsin III 0.309566
OTX2 orthodenticle homeobox 2 0.309566
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.307033
BCL2L13 BCL2-like 13 (apoptosis facilitator) 0.306672
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 0.305948
PADI2 peptidyl arginine deiminase, type II 0.304864
C5 complement component 5 0.304503
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 0.304142
PRCD progressive rod-cone degeneration 0.303059
C7 complement component 7 0.302337
GPR183 G protein-coupled receptor 183 0.301976
FILIP1L filamin A interacting protein 1-like 0.299092
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 0.298731
CLIC6 chloride intracellular channel 6 0.297291
AGTR1 angiotensin II receptor, type 1 0.297291
ADIPOR1 adiponectin receptor 1 0.296571
IL1B interleukin 1, beta 0.295492
STAT1 signal transducer and activator of transcription 1, 91kDa 0.295132
JUN jun proto-oncogene 0.291898
TMEM45A transmembrane protein 45A 0.289744
SUCNR1 succinate receptor 1 0.289027
THY1 Thy-1 cell surface antigen 0.289027
COL4A2 collagen, type IV, alpha 2 0.283655
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.280439
RPN2 ribophorin II 0.280082
HMOX2 heme oxygenase 2 0.278654
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.277584
NXNL1 nucleoredoxin-like 1 0.27687
IGF2-AS IGF2 antisense RNA 0.275801
CLIC1 chloride intracellular channel 1 0.274732
ATF4 activating transcription factor 4 0.273664
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 0.273308
ADGRG2 adhesion G protein-coupled receptor G2 0.27153
TXN2 thioredoxin 2 0.271174
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 0.270819
IL6 interleukin 6 0.269043
CDHR1 cadherin-related family member 1 0.266203
TYRO3 TYRO3 protein tyrosine kinase 0.265494
TGFB1 transforming growth factor, beta 1 0.263014
CD200R1 CD200 receptor 1 0.26266
ANGPT2 angiopoietin 2 0.261245
CHM choroideremia (Rab escort protein 1) 0.25983
RBP4 retinol binding protein 4, plasma 0.259477
RSAD2 radical S-adenosyl methionine domain containing 2 0.25877
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.257005
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.256652
F8 coagulation factor VIII, procoagulant component 0.255946
RORA RAR-related orphan receptor A 0.254888
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.25207
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.25207
SMOC2 SPARC related modular calcium binding 2 0.24715
RGR retinal G protein coupled receptor 0.246799
RRH retinal pigment epithelium-derived rhodopsin homolog 0.246799
CREM cAMP responsive element modulator 0.246098
TYR tyrosinase 0.245747
NRP2 neuropilin 2 0.243645
APITD1 apoptosis-inducing, TAF9-like domain 1 0.242245
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.241196
PYDC1 PYD (pyrin domain) containing 1 0.240847
COTL1 coactosin-like F-actin binding protein 1 0.240847
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.240847
AGER advanced glycosylation end product-specific receptor 0.240497
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.240148
PRPF31 pre-mRNA processing factor 31 0.23945
DDIT3 DNA-damage-inducible transcript 3 0.23945
RGS11 regulator of G-protein signaling 11 0.238752
CLU clusterin 0.238752
PPARG peroxisome proliferator-activated receptor gamma 0.238403
CLDN3 claudin 3 0.236312
GRK1 G protein-coupled receptor kinase 1 0.23492
EPHA7 EPH receptor A7 0.234573
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.233878
TMCO1 transmembrane and coiled-coil domains 1 0.233183
PDGFC platelet derived growth factor C 0.232489
INVS inversin 0.232142
NDP Norrie disease (pseudoglioma) 0.231795
VDAC3 voltage-dependent anion channel 3 0.227988
DDIT4 DNA-damage-inducible transcript 4 0.227988
MT1M metallothionein 1M 0.225229
TNXB tenascin XB 0.223853
HBA1 hemoglobin, alpha 1 0.220766
CRYBB2 crystallin, beta B2 0.21974
MT4 metallothionein 4 0.218034
TNXA tenascin XA (pseudogene) 0.217352
GCLM glutamate-cysteine ligase, modifier subunit 0.217352
GPX3 glutathione peroxidase 3 0.216672
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.216332
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 0.215992
CNGA3 cyclic nucleotide gated channel alpha 3 0.215653
DNTT DNA nucleotidylexotransferase 0.214636
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.212945
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.209583
SCARB2 scavenger receptor class B, member 2 0.208245
OMD osteomodulin 0.208245
RBMS2 RNA binding motif, single stranded interacting protein 2 0.20658
CCL11 chemokine (C-C motif) ligand 11 0.205585
ANXA2 annexin A2 0.204593
HEYL hes-related family bHLH transcription factor with YRPW motif-like 0.204263
HBA2 hemoglobin, alpha 2 0.201635
PLIN2 perilipin 2 0.199033
CD36 CD36 molecule (thrombospondin receptor) 0.194548
RAB40AL RAB40A, member RAS oncogene family-like 0.192031
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.190786
SELE selectin E 0.190786
SON SON DNA binding protein 0.189244
MYO7A myosin VIIA 0.188632
GUCA1B guanylate cyclase activator 1B (retina) 0.188326
ADIPOR2 adiponectin receptor 2 0.187415
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 0.18472
BAK1 BCL2-antagonist/killer 1 0.182375
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.182086
TFR2 transferrin receptor 2 0.181222
GSTM5 glutathione S-transferase mu 5 0.179802
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.179239
GABPB1 GA binding protein transcription factor, beta subunit 1 0.179239
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.177851
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.177029
ANK1 ankyrin 1, erythrocytic 0.177029
DNAH8 dynein, axonemal, heavy chain 8 0.176215
TLR2 toll-like receptor 2 0.174093
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.173832
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.173571
MASP2 mannan-binding lectin serine peptidase 2 0.172291
CLIC4 chloride intracellular channel 4 0.171286
PSIP1 PC4 and SFRS1 interacting protein 1 0.171286
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 0.170299
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.170299
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.169812
TFEB transcription factor EB 0.168854
LRP5 low density lipoprotein receptor-related protein 5 0.164786
LPCAT2 lysophosphatidylcholine acyltransferase 2 0.164149
MUTYH mutY homolog 0.163938
CLDN5 claudin 5 0.163729
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.163317
BMP4 bone morphogenetic protein 4 0.163317
CALB1 calbindin 1, 28kDa 0.162908
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 0.162306
ELOVL5 ELOVL fatty acid elongase 5 0.162109
EFTUD2 elongation factor Tu GTP binding domain containing 2 0.161912
CRABP2 cellular retinoic acid binding protein 2 0.161716
IL17A interleukin 17A 0.161716
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.161523
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 0.160574
BCL2L1 BCL2-like 1 0.159302
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 0.159124
BEND3 BEN domain containing 3 0.158778
BBC3 BCL2 binding component 3 0.158605
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.158434
CLCA4 chloride channel accessory 4 0.143301
CLCA2 chloride channel accessory 2 0.142989
CLCA1 chloride channel accessory 1 0.141943
MATK megakaryocyte-associated tyrosine kinase 0.140371
PCM1 pericentriolar material 1 0.14011
DPT dermatopontin 0.136457
LCK LCK proto-oncogene, Src family tyrosine kinase 0.134372
SOX8 SRY (sex determining region Y)-box 8 0.132385
DDB1 damage-specific DNA binding protein 1, 127kDa 0.13212
COL4A5 collagen, type IV, alpha 5 0.131139
MERTK MER proto-oncogene, tyrosine kinase 0.130944
GATA4 GATA binding protein 4 0.130745
C1ORF174 chromosome 1 open reading frame 174 0.130445
OTX1 orthodenticle homeobox 1 0.130402
PRPF3 pre-mRNA processing factor 3 0.130104
PRPF8 pre-mRNA processing factor 8 0.129981
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 0.129717
ANO1 anoctamin 1, calcium activated chloride channel 0.129282
EYS eyes shut homolog (Drosophila) 0.128371
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.128018
PYGM phosphorylase, glycogen, muscle 0.127557
PTPRB protein tyrosine phosphatase, receptor type, B 0.126705
AGTR2 angiotensin II receptor, type 2 0.126228
MYRF myelin regulatory factor 0.12537
VSIG4 V-set and immunoglobulin domain containing 4 0.12506
TRPM1 transient receptor potential cation channel, subfamily M, member 1 0.124929
C1S complement component 1, s subcomponent 0.124612
CEL carboxyl ester lipase 0.124612
BACE2 beta-site APP-cleaving enzyme 2 0.124595
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 0.124493
ADAM9 ADAM metallopeptidase domain 9 0.124392
SQSTM1 sequestosome 1 0.124375
RAP1B RAP1B, member of RAS oncogene family 0.124307
PLEC plectin 0.124203
TGOLN2 trans-golgi network protein 2 0.124115
IGFALS insulin-like growth factor binding protein, acid labile subunit 0.12401
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.12401
HMGB1 high mobility group box 1 0.123975
ELF5 E74-like factor 5 (ets domain transcription factor) 0.12394
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 0.123818
FRK fyn-related Src family tyrosine kinase 0.123712
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.123676
SNAP91 synaptosomal-associated protein, 91kDa 0.12364
MANF mesencephalic astrocyte-derived neurotrophic factor 0.123586
MBD2 methyl-CpG binding domain protein 2 0.123567
F10 coagulation factor X 0.123441
SLC7A4 solute carrier family 7, member 4 0.123386
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 0.123001
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.122814
RAP1GAP RAP1 GTPase activating protein 0.122455
PHF12 PHD finger protein 12 0.121207
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.120897
SKAP2 src kinase associated phosphoprotein 2 0.118844
SRSF2 serine/arginine-rich splicing factor 2 0.117838
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.11757
CD200 CD200 molecule 0.1174
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.116631
RAP1A RAP1A, member of RAS oncogene family 0.115368
CCL24 chemokine (C-C motif) ligand 24 0.114287
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.114232
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.113535
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.11328
PRDM16 PR domain containing 16 0.113251
HADH hydroxyacyl-CoA dehydrogenase 0.113251
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.112237
CDK11A cyclin-dependent kinase 11A 0.111762
VIM vimentin 0.110946
EPAS1 endothelial PAS domain protein 1 0.110666
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.10797
CCR4 chemokine (C-C motif) receptor 4 0.107565
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.107363
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.107228
TFG TRK-fused gene 0.106749
SRSF1 serine/arginine-rich splicing factor 1 0.106368
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 0.106022
WIF1 WNT inhibitory factor 1 0.105456
FTO fat mass and obesity associated 0.104088
PDGFB platelet-derived growth factor beta polypeptide 0.102977
PDC phosducin 0.102147
SOX10 SRY (sex determining region Y)-box 10 0.102032
CD44 CD44 molecule (Indian blood group) 0.102032
MMP11 matrix metallopeptidase 11 0.101266
RXRA retinoid X receptor, alpha 0.100482
MMP10 matrix metallopeptidase 10 0.100404
C1QBP complement component 1, q subcomponent binding protein 0.100325
RRM2 ribonucleotide reductase M2 0.100208
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.099049
TPT1 tumor protein, translationally-controlled 1 0.097372
GLS glutaminase 0.097372
AMH anti-Mullerian hormone 0.095346
RPE ribulose-5-phosphate-3-epimerase 0.094354
PLEK pleckstrin 0.093571
HAND1 heart and neural crest derivatives expressed 1 0.09264
FGF4 fibroblast growth factor 4 0.09143
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.091295
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.090979
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.090617
GRIP1 glutamate receptor interacting protein 1 0.090525
UNG uracil-DNA glycosylase 0.090295
GUCA1A guanylate cyclase activator 1A (retina) 0.090157
ELOVL2 ELOVL fatty acid elongase 2 0.090065
TAS2R38 taste receptor, type 2, member 38 0.090019
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.089973
PRELP proline/arginine-rich end leucine-rich repeat protein 0.089744